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DESCRIPTION (provided by applicant): Our application is for partial financial support for the Gordon Research Conference on Ca2+ signaling. The conference will be held on June 21-26, 2009 at Il Ciocco Hotel (Near Lucca, Italy). This conference will be the 9th in this series of Gordon Research Conferences. The broad goal of this conference is to facilitate understanding of the molecular and cellular mechanisms of Ca2+ homeostasis and to elucidate physiological and pathological effects produced by this important ion-messenger. Specific objectives for this meeting are: To bring together researchers specialising in fundamental aspects of calcium signaling and scientists with interests in the role of Ca2+ in physiological processes and in important diseases e.g. cardiovascular diseases, cancer, pancreatitis, Alzheimer's disease and others. To develop a stimulating program by inviting speakers and session chairs selected from among the leaders and innovators in the Ca2+ signaling research field (35-40 scientists in total). To attract a further 115 participants with strong interests in Ca2+ signaling who will benefit from cutting-edge lectures and extensive unhampered discussions, as well as from presenting and discussing their research work at poster sessions. To achieve a balanced participation of different groups of scientists (e.g. postdoctoral scientists, young group leaders, established investigators) and to give a fair opportunity for women, under represented minorities and persons with disabilities to participate and present at this meeting. The significance of this conference is that it is an essential biannual discussion forum critical for progress in the understanding of the fundamental mechanisms of Ca2+ signaling and the downstream physiological and pathological processes controlled by this important second messenger. The health relatedness. The Program will contain a session specifically dedicated to the role of Ca2+ signaling in disease. We will discuss the role of Ca2+ signaling in cancer, cardiac hypertrophy, pancreatitis and Alzheimer's disease. We anticipate that this session will help to reveal links between specific signaling mechanisms, which will be discussed in later sessions, with implications for important diseases. (End of Abstract)
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Endoplasmic Reticulum-to-Mitochondria Calcium Transfer in Pancreatic Cancer Development, Metastasis, and Treatment
  • 批准号:
    10679078
  • 项目类别:
  • 资助金额:
    $51.61万
  • 财政年份:
    2021
  • 负责人:
    James Kevin FOSKETT
  • 依托单位:
Endoplasmic Reticulum-to-Mitochondria Calcium Transfer in Pancreatic Cancer Development, Metastasis, and Treatment
  • 批准号:
    10443604
  • 项目类别:
  • 资助金额:
    $51.61万
  • 财政年份:
    2021
  • 负责人:
    James Kevin FOSKETT
  • 依托单位:
Molecular physiology of intracellular InsP3R and MCU ion channels
  • 批准号:
    10614508
  • 项目类别:
  • 资助金额:
    $44.69万
  • 财政年份:
    2021
  • 负责人:
    James Kevin FOSKETT
  • 依托单位:
Endoplasmic Reticulum-to-Mitochondria Calcium Transfer in Pancreatic Cancer Development, Metastasis, and Treatment
  • 批准号:
    10208636
  • 项目类别:
  • 资助金额:
    $52.66万
  • 财政年份:
    2021
  • 负责人:
    James Kevin FOSKETT
  • 依托单位:
国内基金
海外基金
新型F-18标记香豆素衍生物PET探针的研制及靶向Alzheimer's Disease 斑块显像研究
  • 批准号:
    81000622
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    20.0万元
  • 批准年份:
    2010
  • 负责人:
    梁胜
  • 依托单位:
阿尔茨海默病(Alzheimer's disease,AD)动物模型构建的分子机理研究
  • 批准号:
    31060293
  • 项目类别:
    地区科学基金项目
  • 资助金额:
    26.0万元
  • 批准年份:
    2010
  • 负责人:
    郭亚芬
  • 依托单位:
跨膜转运蛋白21(TMP21)对引起阿尔茨海默病(Alzheimer'S Disease)的γ分泌酶的作用研究