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Diabetic Foot Imaging Scanner(DFIS)

糖尿病足影像扫描仪(DFIS)

基本信息

批准号：
7667120
负责人：
Jeffrey Norman Schoess
金额：
$ 13.35万
依托单位：
EDEN MEDICAL, INC.
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-07-01 至 2010-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7667120
关键词：
Academic Medical Centers Acer Affect Air Algorithms Area Arizona Autolysis Behavior Bone callus Calibration Caring Clinical Collection Complex Computer software Data Dermal Development Diabetic Foot Diabetic Foot Ulcer Diagnosis Diagnostic Disease Doctor of Philosophy Early Diagnosis Early identification Engineering Foot Ulcer Functional disorder Funding Goals Hand Health Personnel Healthcare Heating Home environment Hot Spot Housing Image Imagery Imaging technology Immersion Investigative Technique Incidence Inflammation Injury Intervention Knee joint Knowledge Lead Licensing Limb Salvage Limb structure Measures Mechanics Medical Electronics Medicine Monitor Motivation Motor National Health Interview Survey Neuropathy Obesity Odors Operative Surgical Procedures Pain Pathologic Processes Pathology Patients Phase Physical activity Positioning Attribute Predisposition Protocols documentation Randomized Clinical Trials Recruitment Activity Redness Research Risk Scientist Shapes Skin Skin Temperature Small Business Innovation Research Grant Solutions Stratification Stress Support System Surrogate Markers Swelling System Temperature Testing Thermometers Thermometry Thermoreceptors Time Tissues Ulcer Universities Veterans Vision Visual Work aging population base college commercial application commercialization computerized data processing design diabetic patient evidence base experience foot health related quality of life high risk human subject image processing image registration intervention effect loss of function prevent product development prototype public health relevance research clinical testing response software development tool wound

项目摘要

DESCRIPTION (provided by applicant): Korosensor.com, Inc. (KI) proposes this Phase 1 SBIR proposal to develop an infrared "Diabetic Foot Imaging Scanner (DFIS)" to reduce the incidence of foot ulcers for high-risk diabetic patients. Diabetic foot wounds are common, complex and costly. They are frequently caused by repetitive stress to the foot, causing inflammation and skin breakdown. The key focus is to provide early detection of potentially damaging inflammation and corrective treatment (I.e. allow the patient to modify personal activity) to prevent ulceration. The key goal of the proposed Phase I project is to test the hypothesis that the DFIS system correlated with the clinical signs of skin breakdown demonstrates the ability to reduce the incidence of diabetic foot ulcers in high-risk diabetic patients. A secondary objective is to measure the effect of the intervention in terms of health-related quality of life. These objectives will be accomplished through specific tasks including: hardware design of foot imaging scanner, development of image acquisition protocol and data processing algorithms to collect infrared data, provide user interface support, system control and calibration, assembly of a testbed to demonstrate infrared imaging technology for reduction of ulceration incidence, and human subject testing at the College of Medicine at the University of Arizona. PUBLIC HEALTH RELEVANCE: DFIS The key focus for the development of the Diabetic Foot Imaging Scanner (DFIS) is provide early identification of the cardinal signs of inflammation (redness, swelling, and excessive heat) leading to ulceration. The correlation of infrared imagery with treatment-based diabetic foot data to determine patient risk and course of action. The DFIS will demonstrate the ability to identify hot spots associated with repetitive stress to provide early warning of ulceration formation. A comprehensive analysis of pathological changes of dynamic behavior (i.e. cooling immersion of an area of susceptibility) to assess response of thermoreceptors will be performed during human subject testing.

描述（由申请人提供）：Korosensor.com，Inc. (KI)提出了这一阶段SBIR建议，以开发红外“糖尿病足成像扫描仪（DFIS）”，以减少高风险糖尿病患者的足部溃疡的发病率。糖尿病足伤口是常见的，复杂的和昂贵的。它们通常是由对足部的重复压力引起的，引起炎症和皮肤破裂。重点是提供早期检测潜在的破坏性炎症和纠正治疗（即允许患者改变个人活动），以防止溃疡。拟议的I期项目的主要目标是检验以下假设：与皮肤破裂的临床体征相关的DFIS系统证明了降低高危糖尿病患者糖尿病足溃疡发生率的能力。第二个目标是衡量干预措施对健康相关生活质量的影响。这些目标将通过具体的任务来实现，包括：足部成像扫描仪的硬件设计，图像采集协议和数据处理算法的开发，以收集红外数据，提供用户界面支持，系统控制和校准，测试台的组装，以展示红外成像技术，以减少溃疡的发生率，以及在亚利桑那大学医学院进行的人体受试者测试。公共卫生相关性：DFIS糖尿病足成像扫描仪（DFIS）开发的重点是提供早期识别导致溃疡的炎症的主要体征（发红、肿胀和过热）。红外成像与基于治疗的糖尿病足数据的相关性，以确定患者风险和行动过程。DFIS将展示识别与重复性应激相关的热点的能力，以提供溃疡形成的早期预警。在人类受试者试验期间，将对动态行为的病理变化（即易感区域的冷却浸没）进行全面分析，以评估温度感受器的反应。