Foot Infrared Rolling Scan Transducer (FIRST)

描述(由申请人提供)：首先，足部红外滚动扫描传感器(First)将执行可见光/近红外(NIR)光谱成像，以量化脱氧血红蛋白(Deoxy-Hb)和氧合血红蛋白(oxy-Hb)的水平，这些水平表明潜在的皮肤浮肿、红斑和微循环丧失。这种手持设备将在日常足部自我检查中使用，以鼓励糖尿病患者评估可能导致溃疡发生的潜在皮肤破裂问题。关键的重点是及早评估潜在的溃疡和矫正治疗(即患者个人活动的剂量)，以防止皮肤破裂。体内监测将以三波长测量的形式进行，评估足部组织中脱氧-Hb和氧合-Hb吸收的变化。光线将通过滚动的扫描头投射到患者的脚上，专用的光探测器将在光线与组织相互作用后接收光线。 公共卫生相关性：首先，重点是及早评估潜在的溃疡和纠正治疗(即患者个人活动的剂量)，以防止皮肤破裂。体内监测将以三波长测量的形式进行，评估足部组织中脱氧-Hb和氧合-Hb吸收的变化。

DESCRIPTION (provided by applicant): FIRST The Foot Infrared Rolling Scan Transducer (FIRST) will perform visible/near- infrared (NIR) spectral imaging to quantify the levels of deoxygenated hemoglobin (deoxy-Hb) and oxygenated hemoglobin (oxy-Hb) that indicate potential for cutaneous edema, erythema, and microcirculation loss. The hand- held device will be used during daily foot self-exams to encourage diabetic patients to assess potential skin breakdown problems that can cause ulceration to occur. The key focus is to provide early assessment of potential ulceration and corrective treatment (i.e. dosage of patient personal activity) to prevent skin breakdown. In vivo monitoring will be performed as a triple wavelength measurement assessing changes in absorption of deoxy-Hb and oxy-Hb in foot tissue. Light will be projected into the patient's foot through a rolling scanner head and dedicated light detectors will receive the light after it has interacted with the tissue. PUBLIC HEALTH RELEVANCE: FIRST The key focus is to provide early assessment of potential ulceration and corrective treatment (i.e. dosage of patient personal activity) to prevent skin breakdown. In vivo monitoring will be performed as a triple wavelength measurement assessing changes in absorption of deoxy-Hb and oxy-Hb in foot tissue.