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Foot Infrared Rolling Scan Transducer (FIRST)

脚部红外滚动扫描传感器（第一）

基本信息

批准号：
7908292
负责人：
Jeffrey Norman Schoess
金额：
$ 14.81万
依托单位：
EDEN MEDICAL, INC.
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-04-05 至 2013-09-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7908292
关键词：
Academic Medical Centers Address Affect Algorithms Area Arizona Behavior Biomechanics Blood Vessels Bone callus California Caring Clinical Complex Computer software Coupled Cutaneous Data Dermal Development Device or Instrument Development Devices Diabetic Angiopathies Diabetic Foot Diabetic Foot Ulcer Diagnosis Disease Doctor of Philosophy Early Diagnosis Early identification Edema Electronics Engineering Environment Erythema Esthesia Foot Ulcer Functional disorder Funding Goals Hand Head Health Health Personnel Healthcare Hemoglobin Home environment Hyperemia Image Imagery Incidence Inflammation Injury Intervention Knee joint Knowledge Lead Light Limb Salvage Measurement Measures Mechanics Medicine Metabolic Microcirculation Modality Monitor Motivation National Health Interview Survey Nature Neuropathy Obesity Odors Operative Surgical Procedures Optics Pathologic Processes Patients Perfusion Phase Physical activity Predisposition Preventive Process Protocols documentation Randomized Clinical Trials Recording of previous events Recruitment Activity Redness Research Risk Risk Assessment Role Scanning Scientist Skin Skin Temperature Skin Tissue Small Business Innovation Research Grant Solutions Stratification Stress Surface Swelling System Temperature Testing Thermometers Thermometry Time Tissues Transducers Tube Ulcer Universities Validation Vision Visual Work absorption aging population base clinical efficacy college commercial application commercialization data acquisition design detector diabetic diabetic patient dosage evidence base experience foot health related quality of life hemodynamics high risk human subject image processing in vivo indexing interest intervention effect laptop novel prevent prototype public health relevance research clinical testing response shear stress software development theories therapy design tissue oxygenation tool wound

项目摘要

DESCRIPTION (provided by applicant): FIRST The Foot Infrared Rolling Scan Transducer (FIRST) will perform visible/near- infrared (NIR) spectral imaging to quantify the levels of deoxygenated hemoglobin (deoxy-Hb) and oxygenated hemoglobin (oxy-Hb) that indicate potential for cutaneous edema, erythema, and microcirculation loss. The hand- held device will be used during daily foot self-exams to encourage diabetic patients to assess potential skin breakdown problems that can cause ulceration to occur. The key focus is to provide early assessment of potential ulceration and corrective treatment (i.e. dosage of patient personal activity) to prevent skin breakdown. In vivo monitoring will be performed as a triple wavelength measurement assessing changes in absorption of deoxy-Hb and oxy-Hb in foot tissue. Light will be projected into the patient's foot through a rolling scanner head and dedicated light detectors will receive the light after it has interacted with the tissue. PUBLIC HEALTH RELEVANCE: FIRST The key focus is to provide early assessment of potential ulceration and corrective treatment (i.e. dosage of patient personal activity) to prevent skin breakdown. In vivo monitoring will be performed as a triple wavelength measurement assessing changes in absorption of deoxy-Hb and oxy-Hb in foot tissue.

描述（由申请人提供）：首先，足部红外滚动扫描传感器（FIRST）将进行可见/近红外（NIR）光谱成像，以量化脱氧血红蛋白（deoxy-Hb）和氧合血红蛋白（oxy-Hb）的水平，这表明可能出现皮肤水肿、红斑和微循环丧失。这种手持设备将用于每日足部自我检查，以鼓励糖尿病患者评估可能导致溃疡发生的潜在皮肤破裂问题。重点是提供潜在溃疡的早期评估和纠正治疗（即患者个人活动的剂量），以防止皮肤破裂。体内监测将作为三波长测量进行，评估足部组织中脱氧血红蛋白和氧合血红蛋白吸收的变化。光将通过滚动扫描仪头投射到患者的足部，专用光探测器将在光与组织相互作用后接收光。公共卫生相关性：首先，重点是提供潜在溃疡的早期评估和纠正治疗（即患者个人活动的剂量），以防止皮肤破裂。体内监测将作为三波长测量进行，评估足部组织中脱氧血红蛋白和氧合血红蛋白吸收的变化。