癌症和白血病 B 组-猫眼课题宝

癌症和白血病 B 组

批准号：

7892673

负责人：

RICHARD L SCHILSKY

金额：

$20.14万

依托单位：

UNIVERSITY OF CHICAGO

依托单位国家：

美国

项目类别：

财政年份：

2009

资助国家：

美国

项目状态：

已结题

起止时间：

2009-06-01 至 2010-03-31

来源：

https://reporter.nih.gov/project-details/7892673

关键词：

18 year old Academic Medical Centers Achievement Acute leukemia Address Adjuvant Adjuvant Chemotherapy Adjuvant Therapy Adolescent Adopted Adverse event Advisory Committees Advocate Affect African American Age Allogenic Am 580 American College of Radiology Imaging Network American Society of Clinical Oncology Ancillary Study Antibodies Antineoplastic Agents Applications Grants Archives Area Arsenic Trioxide Arts Attention Autologous Autologous Stem Cell Transplantation Award Azacitidine BCL2 gene Basic Science Behavioral Sciences Biological Biological Assay Biological Markers Biological Markers Biological Products Biologically Based Therapy Biology Bone Density Bone Marrow Transplantation Breast Breast Cancer Prevention Budgets Busulfan CD3 Antigens California Cancer Biology Cancer Control Cancer Patient Cancer Survivor Cancer and Leukemia Group B Candidate Disease Gene Caregivers Caring Categories Cell Transplants Cells Certification Chairperson Characteristics Chemotherapy-Oncologic Procedure Chest Chicago Children&apos s Oncology Group Chimerism Cisplatin Classification Clinical Clinical Pharmacology Clinical Research Clinical Research Associate Clinical Trials Clinical Trials Cooperative Group Clinical Trials Data Monitoring Committees Clinical Trials Design Clinical Trials Network Collaborations Colon Carcinoma Colorectal Cancer Commit Committee Members Communication Communities Community Clinical Oncology Program Community Hospitals Comorbidity Companions Complex Computer software Concept Review Consent Controlled Clinical Trials Core Facility Correlative Study Counseling Credentialing Critiques DNA DNA Microarray Chip Data Data Analyses Data Collection Data Set Databases Dependency Development Diagnosis Diagnostic Discipline Discipline of Nursing Disease Disease remission Disease-Free Survival Disorder by Site Documentation Dose Drug Evaluation Drug Formulations Drug Industry Drug Kinetics Drug resistance Dysmyelopoietic Syndromes ERBB2 gene Early Diagnosis Eastern Cooperative Oncology Group Economics Education Elderly Elements Eligibility Determination Enrollment Ensure Enzymes Epidemiology Equilibrium Esophageal Ethnic group Evaluation Event Evolution Exhibits Face Faculty Feedback Follicular Lymphoma Fostering Freezing Functional disorder Funding Future Generations Genes Genetic Polymorphism Genitourinary system Geriatric Assessment Goals Grant Group Processes Health Health Services Healthcare Hematopoietic Hispanics Histology Hodgkin Disease Homologous Transplantation Hospitals Hour Human Resources Image Imaging technology Immune Immunophenotyping Incidence Individual Inferior Institutes Institution International Intervention Investigational New Drug Application Kidney Knowledge Laboratories Laboratory Study Latino Lead Leadership Learning Length Libraries Link Living Costs Location Lung Lymphedema Lymphography Lymphoma Magnetic Resonance Imaging Maintenance Malignant Neoplasms Malignant neoplasm of lung Malignant neoplasm of pancreas Malignant neoplasm of prostate Malignant neoplasm of testis Malignant neoplasm of urinary bladder Manuscripts Maximum Tolerated Dose Measurement Medical Medical Oncologist Medicine Mentors Mesothelioma Methodology Micrometastasis Microscopy Minority Mission Modality Modeling Molecular Molecular Analysis Molecular Cytogenetics Molecular Profiling Molecular Target Monitor Monoclonal Antibodies Monoclonal Antibody Therapy Morbidity - disease rate Multiple Myeloma Mutation NCI Board of Scientific Advisors Names Natural History Nelarabine Neoadjuvant Therapy Nephrectomy New Agents Newly Diagnosed Non-Small-Cell Lung Carcinoma North Carolina North Central Cancer Treatment Group Nurses Nursing Societies Observational Study Office for Human Research Protections Ohio Oncologic Nursing Oncology Nurse Online Systems Operative Surgical Procedures Oral Organ Outcome P-Glycoprotein P-Glycoproteins PET/CT scan Paclitaxel Pain Paper Paraffin Embedding Participant Pathologist Pathology Patient Care Patient Outcomes Assessments Patient Recruitments Patients Pattern Peer Review Pelvis Performance Peripheral Nervous System Diseases Personal Satisfaction Pharmaceutical Preparations Pharmacists Pharmacodynamics Pharmacogenetics Pharmacogenomics Pharmacology Phase Phase I Clinical Trials Phase I/II Trial Phase II Clinical Trials Phase III Clinical Trials Physicians Pilot Projects Plasma Play Policies Population Population Sciences Positioning Attribute Positron-Emission Tomography Postdoctoral Fellow Preparation Prevention Preventive Intervention Principal Investigator Procedures Process Productivity Prognostic Marker Prostate Proteins Protocols documentation Publications Publishing Pulmonology Qualifying Quality Control Quality of life Radiation Oncologist Radiation Oncology Radiation therapy Radiology Specialty Randomized Clinical Trials Randomized Controlled Clinical Trials Recommendation Recording of previous events Records Recruitment Activity Recurrent disease Regulatory Affairs Relapse Relative (related person)Renal Cell Carcinoma Renal carcinoma Reporting Request for Applications Research Research Activity Research Design Research Ethics Committees Research Infrastructure Research Personnel Research Project Grants Residual Neoplasm Resistance Resources Revlimid Risk Role Safety Sample Size Sampling San Francisco Schedule Science Scientist Seasons Secure Series Services Signal Pathway Site Site Visit Social Adjustment Solid Solid Neoplasm Southwest Oncology Group Specific qualifier value Staging Stem cells Structure Supportive care Surface Antigens Surgeon Surgical Oncology Surveys Survival Rate Survivors Symptoms System Systemic Therapy T-Lymphocyte Tamoxifen Techniques Technology Telephone Testing Therapeutic Therapeutic Index Therapeutic Studies Therapeutics Committee Therapy Clinical Trials Thoracic Surgical Procedures Time Tissue Banking Tissue Banks Tissue Sample Tissues Toxic effect Training Training Activity Translational Research Translational Research Working Group Transplantation Trastuzumab Travel Treatment Efficacy Treatment Protocols Treatment outcome Triage Tumor Angiogenesis Tumor Biology Tumor Markers Tumor Tissue Uncertainty Underrepresented Minority Underserved Population United States Universities University of Chicago Cancer Research Center Update Upper arm Urine Urogenital Cancer Urology Vascular Endothelial Growth Factors Veterans Vision Woman Work Writing Zoledronic Acid abstracting advanced disease age group anticancer research base bevacizumab biobank bisphosphonate bladder Carcinoma breast lumpectomy breast surgery cancer care cancer imaging cancer prevention cancer surgery cancer therapy cancer type capecitabine career cell killing chemotherapy chronic graft versus host disease clinical practice conditioning cooperative study cost cost effectiveness data collection methodology design disease characteristic drug development evidence base experience falls functional outcomes gastrointestinal gemcitabine genome-wide graft vs host disease health related quality of life high risk hormone therapy human subject protection improved inhibitor/antagonist innovation insight interdisciplinary approach interest irinotecan kidney cell leukemia leukemia/lymphoma malignant breast neoplasm meetings member minimally invasive molecular imaging mortality multidisciplinary named group neoplasm registry neoplasm resource neoplastic cell new technology novel novel strategies novel therapeutics nursing intervention older patient older women oncology organizational structure outcome forecast patient population population based prevent professor progesterone 11-hemisuccinate-(2-iodohistamine)programs protocol development quality assurance radiologist research clinical testing respiratory response skills small molecule standard care standard of care statistical center stem success survivorship symptom management technology/technique time use tool transmission process treatment response treatment strategy treatment trial trial comparing tumor tumor progression urinary gonadotropin fragment virtual working group young adult

项目摘要

项目成果

RICHARD L SCHILSKY的其他基金

相似基金

相关文献

中文摘要

翻译

点击翻译按钮获取中文摘要

英文摘要

DESCRIPTION (Provided by applicant): The CALGB is comprised of 26 academic medical centers and over 200 affiliated community hospitals joined in the pursuit of improved cancer treatment and better understanding of tumor biology and cancer treatment outcomes via the conduct of controlled clinical trials. Over 4,000 members of the Group including oncology physicians, radiologists, pathologists, statisticians, clinical research associates, oncology nurses, pharmacists, health outcomes researchers, and basic scientists participate in these studies. From 25-30 phase III protocols are active at any one time, along with phase II and phase I studies that provide preliminary data required for the appropriate design of large scale randomized trials. Multidisciplinary disease committees of the Group design and implement protocols for the treatment of patients with leukemia, lymphoma, breast, respiratory, Gl and GU cancer. Modality committees, including Leukemia Correlative Sciences, Imaging, Pharmacology and Experimental Therapeutics, Surgery, Transplant, Cancer in the Elderly, Cancer Control and Health Outcomes, and Oncology Nursing provide expertise that enhances the contribution of these disciplines to CALGB studies. Scientific resources committees, including Clinical Research Associates, Pathology and Radiation Oncology, provide essential quality assurance and training activities for the Group. Major areas of emphasis in CALGB include development of innovative treatments for patients with cancer; studies of molecular predictors of prognosis and response to therapy; studies of the pharmacokinetics, pharmacodynamics and pharmacogenetics of new and established anticancer drugs; evaluation of minimally invasive surgical techniques and novel imaging technologies; determining the cost and cost-effectiveness of new cancer therapies; evaluating the impact of cancer and its treatment on the quality of life of cancer patients and their caregivers; developing new strategies for cancer prevention; and addressing the needs of special populations, particularly minorities and the elderly. A new core facility in cancer imaging was established to provide central review and archiving of PET and CT images and to set standards for image acquisition and transmission at CALGB institutions. Three new molecular reference laboratories are proposed in this application to provide biomarker assessments that are necessary to determine patient eligibility or treatment assignment in CALGB studies of targeted therapies. Three established biorepositories collect, archive and distribute frozen and paraffin-embedded solid tumor tissues, leukemia cells, plasma, serum, urine and DNA for correlative science studies.

期刊论文(0)

专著(0)

科研奖励(0)

会议论文