Diabetic Retinopathy Clinical Research Network Coordinating Center

描述（由申请人提供）：本申请是为糖尿病视网膜病变临床研究网络（DRCR.net）协调中心提供五年延长资助。DRCR.net的目标是开发和维护一个协作网络，以促进对糖尿病视网膜病变、糖尿病黄斑水肿和相关疾病的多中心临床研究，这些疾病是美国和世界各地视力损害和失明的主要和不断增长的原因。它的优先事项包括以社区为基础的做法以及大学为基础的中心的参与，并与行业合作，以促进调查和机会，否则是不可能的，但这样做的方式符合网络的学术诚信和最佳临床试验性能的奉献精神。协调中心在该网络实现其目标的能力方面发挥着关键作用。在下一个供资周期，该网络提议完成在供资期开始时预计正在进行的5项协议，启动大约10项新协议，（每年大约1个新的主要方案和1个新的次要方案）用于糖尿病视网膜病变、糖尿病黄斑水肿和相关疾病，开发和实施视网膜图像电子数据采集的新方法，以促进糖尿病视网膜病变临床试验的进行，DRCR.net通过征求新网站的参与，继续扩大www.example.com，并鼓励我们将继续鼓励最近完成奖学金培训的研究人员参与（见运营中心提案），继续教育DRCR.net研究人员关于临床研究的原则，并指导选定的视网膜专家成为糖尿病视网膜病变和相关疾病临床试验的领导者。

DESCRIPTION (provided by applicant): This application is for a five-year extension of funding for the Diabetic Retinopathy Clinical Research Network (DRCR.net) Coordinating Center. The objective of the DRCR.net is to develop and maintain a collaborative network to facilitate multicenter clinical research on diabetic retinopathy, diabetic macular edema and associated conditions, leading and growing causes of vision impairment and blindness in the United States and throughout the world. Its priorities include involvement of community-based practices as well as university-based centers and to collaborate with industry to facilitate investigations and opportunities otherwise not possible, but to do so in a manner consistent with the Network's dedication to academic integrity and optimal clinical trial performance. The Coordinating Center plays a key role in the Network's ability to achieve its goals. During the next funding cycle, the network proposes to complete 5 protocols that are expected to be in progress at the time the funding period begins, initiate approximately 10 new protocols (approximately 1 new major protocol and 1 new minor protocol per year) in diabetic retinopathy, diabetic macular edema and associated conditions, develop and implement new methods for electronic data capture of retinal images to facilitate the conduct of diabetic retinopathy clinical trials, continue to expand the DRCR.net by soliciting the participation of new sites and encouraging the involvement of investigators who recently have completed fellowship training (see Operations Center proposal), continue to educate the DRCR.net investigators on the principles of clinical research, and mentor selected retina specialists to be leaders in clinical trials with specific reference to diabetic retinopathy and associated diseases.