Objectively monitoring neurodegenerative disease progression: speech as a clinical marker

在某些神经退行性疾病如亨廷顿病或痴呆症中，如果不使用昂贵的侵入性评估技术，很难监测疾病进展。然而，通过反复记录和分析患者的言语（我们如何说话，而不是我们说了什么），我们建立了大脑如何运作和随时间变化的图片。这将带来更加个性化的方法，在正确的时间为正确的患者提供更有效的治疗。

It is difficult to monitor disease progression in some neurodegenerative disorders like Huntington’s disease or types of dementia without using expensive and invasive assessment techniques. Yet, by repeatedly recording and analysing the speech (how we speak, not what we say) of a patient, we build up a picture of how the brain is functioning and changing over time. This will lead to a more personalized approach with more effective treatments being given to the right patients at the right time.