Objectively monitoring neurodegenerative disease progression: speech as a clinical marker

客观监测神经退行性疾病进展：言语作为临床标记

• 批准号: nhmrc : 1012302
• 负责人: A/Pr Adam Vogel
• 金额: $ 20.15万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/objectively-monitoring-neurodegenerative-clinical-marker/109649
• 关键词: Objectively; monitoring; neurodegenerative; disease; progression

It is difficult to monitor disease progression in some neurodegenerative disorders like Huntington’s disease or types of dementia without using expensive and invasive assessment techniques. Yet, by repeatedly recording and analysing the speech (how we speak, not what we say) of a patient, we build up a picture of how the brain is functioning and changing over time. This will lead to a more personalized approach with more effective treatments being given to the right patients at the right time.

如果不使用昂贵的侵入性评估技术，很难监测一些神经退行性疾病的疾病进展，如亨廷顿病或痴呆症类型。然而，通过反复记录和分析病人的讲话(我们如何说话，而不是我们说什么)，我们建立了一幅大脑如何运作和随时间变化的图景。这将导致更个性化的方法，在正确的时间为正确的患者提供更有效的治疗。