Community to Molecular Approaches in Early Screening and Diagnosis to Promote Equitable Outcomes Through the Continuum of Care in Cancer Among Populations of African Ancestry

项目总结 非洲-加勒比癌症联盟(AC3)是福克斯·蔡斯癌症中心的全球肿瘤学项目 并在解决非裔美国人、加勒比人和非洲人之间的癌症差异方面发挥着独特的作用 美国的移民(美国)以及他们在本国的同行。AC3成员资格是跨 学科(基础和人口科学研究人员、临床医生和癌症倡导者)，由三个人组成 互联网络(美国、加勒比海和非洲)。我们2023年会议的主题：“从社区到分子 通过连续护理促进公平结局的早期筛查和诊断方法 非洲裔人口中的癌症“反映了我们成员的跨学科构成。 此外，正如我们在以往会议上所实现的那样，我们的2023年会议组织委员会、演讲者和 观众将充分反映我们会员的多样性。在美国和世界范围内，癌症导致更多黑人死亡 比任何其他种族/民族都要多。大量癌症过早死亡也发生在以黑人为主的地区 撒哈拉以南非洲和加勒比地区的国家。黑人人群中的癌症研究仍然影响深远 不仅在美国，在非洲和加勒比海地区黑人占主导地位的国家也是如此。数量 来自非洲和加勒比地区的生物医学研究出版物正在增加，但差距仍然存在 研究文章集中在癌症上。黑人科学家在NCI资助金中的比例也严重不足 收件人。因此，由训练有素的黑人科学家组成的国际骨干队伍增加了急需的多样性 在全球癌症研究人员中。考虑到美国黑人人口的多样性，美国的癌症研究 加勒比和非洲是包容性的，也是解决美国癌症差异的关键。这是公平的 研究方法在美国将是最有益的，因为这些研究对提供信息和改进至关重要 所有美国黑人的癌症干预、治疗和预防。AC3科学与训练 因此，会议是合理的、及时的和有益的。我们针对癌症的培训、科学交流和 协作规划研讨会将对AC3加速癌症研究、推进 黑人科学家的职业生涯，为研究影响黑人的癌症差异提供了创新机会 在美国。以下是具体目标：1)通过提供专业发展来增强多样性； 教育和科学培训，以加强保健方面的研究、技能和能力 代表不足和服务不足的早期调查人员和学生。2)促进知识交流 在非洲裔人口中推广癌症科学，并增加研究开发和 在黑人群体中协调研究研究。3)以科学提供促进健康公平 严谨、在临床和文化上了解情况的研究，以获得更大的社区利益，以改善 了解癌症风险、降低癌症风险和预防癌症的策略。

PROJECT SUMMARY The African-Caribbean Cancer Consortium (AC3) is a Global Oncology Program at Fox Chase Cancer Center and plays a unique role by addressing cancer disparities involving African American, Caribbean and African immigrants in the United States (U.S.) and their counterparts in native countries. AC3 membership is trans- disciplinary (basic and population science researchers, clinicians, and cancer advocates) and consists of three interconnected networks (U.S., Caribbean and Africa). Our 2023 conference theme: “Community to Molecular Approaches in Early Screening and Diagnosis to Promote Equitable Outcomes Through the Continuum of Care in Cancer Among Populations of African Ancestry” reflects the trans-disciplinary makeup of our membership. Also, as we have achieved in prior conferences, our 2023 conference organizing committees, speakers and audiences will fully reflect the diversity of our membership. In the U.S. and worldwide, cancer kills more Blacks than any other racial/ethnic group. A great number of premature cancer deaths also occur in predominantly Black nations in Sub-Saharan Africa and the Caribbean. Cancer research in Black populations remains profoundly lacking not only in the US but also in Black dominant countries in Africa and the Caribbean. The number of biomedical research publications from Africa and the Caribbean are increasing, but disparities remain for research articles focused on cancer. Black scientists are also grossly underrepresented among NCI grant recipients. Therefore, an international cadre of well-trained Black scientists increases the much needed diversity among global cancer researchers. Considering the diversity of the U.S. Black population, cancer research in the Caribbean and Africa is inclusive and also essential for addressing cancer disparities in the U.S. This equitable approach to research will be most beneficial in the U.S. as these studies are critical to inform and improve interventions, treatment and prevention of cancers among all U.S. Blacks. The AC3 Scientific and Training Conference is therefore justified, timely and useful. Our cancer-focused training, scientific exchange and collaboration planning workshops will be a boon to the AC3 efforts to accelerate cancer research, advance careers of Black scientists and provides innovative opportunities to study cancer disparities that impact Blacks in the US. The following are the Specific Aims: 1) To enhance diversity by providing professional development, education and scientific training, to strengthen health disparities research, skills and competencies among underrepresented and underserved early stage investigators and students. 2) To facilitate knowledge exchange of the science of cancer among African-descent populations, and increase research development and the coordination of research studies in Black populations. 3) To promote health equity by providing scientifically rigorous, and clinically and culturally informed research for greater community benefit in order to improve knowledge, awareness of cancer risk, strategies for cancer risk reduction and prevention.