Community to Molecular Approaches in Early Screening and Diagnosis to Promote Equitable Outcomes Through the Continuum of Care in Cancer Among Populations of African Ancestry

社区采用分子方法进行早期筛查和诊断，通过对非洲裔人群癌症的持续护理来促进公平结果

• 批准号: 10754038
• 负责人: Samuel Gathere
• 金额: $ 2万
• 依托单位: RESEARCH INST OF FOX CHASE CAN CTR
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10754038
• 关键词: Acceleration; Address; Advanced Malignant Neoplasm; Advocate; Africa; Africa South of the Sahara; African; African American; African Caribbean; African ancestry; Applications Grants; Award; Awareness; Basic Science; Biomedical Research; Black Populations; Black race; Cancer Burden; Cancer Control; Cancer Etiology; Cancer Science; Career Mobility; Caribbean region; Centers of Research Excellence; Cessation of life; Clinical; Collaborations; Communities; Competence; Continuity of Patient Care; Country; Development; Diagnosis; Disparity; Early Diagnosis; Education; Educational workshop; Epidemiology; Equity; Ethnic Population; Etiology; Faculty; Fox Chase Cancer Center; Funding; Genomics; Goals; Grant; Health; Health Disparities Research; Immersion; Immigrant; Industry; Inequity; Infectious Agent; Institution; International; Intervention; Jamaica; Kenya; Knowledge; Laboratories; Longitudinal cohort; Malignant Female Reproductive System Neoplasm; Malignant Neoplasms; Malignant neoplasm of prostate; Mentored Research Scientist Development Award; Mentors; Molecular; NIH Program Announcements; National Cancer Institute; National Institute on Minority Health and Health Disparities; Needs Assessment; Oncology; Outcome; Play; Population; Population Density; Population Sciences; Prevention; Productivity; Publications; Publishing; Readiness; Research; Research Personnel; Research Support; Resource-limited setting; Risk Reduction; Role; Science; Scientist; Seminal; Site; Small Business Innovation Research Grant; Small Business Technology Transfer Research; Students; Targeted Research; Teacher Professional Development; Technology; Training; Training Programs; United States; United States National Institutes of Health; Writing; anticancer research; cancer health disparity; cancer prevention; cancer risk; career; career development; community involvement; early screening; effective intervention; experience; global health; health disparity; health equity promotion; health training; improved; improved outcome; innovation; interest; member; mortality; oncology program; outcome disparities; premature; programs; racial population; recruit; research and development; research study; skills; symposium; virtual

PROJECT SUMMARY The African-Caribbean Cancer Consortium (AC3) is a Global Oncology Program at Fox Chase Cancer Center and plays a unique role by addressing cancer disparities involving African American, Caribbean and African immigrants in the United States (U.S.) and their counterparts in native countries. AC3 membership is trans- disciplinary (basic and population science researchers, clinicians, and cancer advocates) and consists of three interconnected networks (U.S., Caribbean and Africa). Our 2023 conference theme: “Community to Molecular Approaches in Early Screening and Diagnosis to Promote Equitable Outcomes Through the Continuum of Care in Cancer Among Populations of African Ancestry” reflects the trans-disciplinary makeup of our membership. Also, as we have achieved in prior conferences, our 2023 conference organizing committees, speakers and audiences will fully reflect the diversity of our membership. In the U.S. and worldwide, cancer kills more Blacks than any other racial/ethnic group. A great number of premature cancer deaths also occur in predominantly Black nations in Sub-Saharan Africa and the Caribbean. Cancer research in Black populations remains profoundly lacking not only in the US but also in Black dominant countries in Africa and the Caribbean. The number of biomedical research publications from Africa and the Caribbean are increasing, but disparities remain for research articles focused on cancer. Black scientists are also grossly underrepresented among NCI grant recipients. Therefore, an international cadre of well-trained Black scientists increases the much needed diversity among global cancer researchers. Considering the diversity of the U.S. Black population, cancer research in the Caribbean and Africa is inclusive and also essential for addressing cancer disparities in the U.S. This equitable approach to research will be most beneficial in the U.S. as these studies are critical to inform and improve interventions, treatment and prevention of cancers among all U.S. Blacks. The AC3 Scientific and Training Conference is therefore justified, timely and useful. Our cancer-focused training, scientific exchange and collaboration planning workshops will be a boon to the AC3 efforts to accelerate cancer research, advance careers of Black scientists and provides innovative opportunities to study cancer disparities that impact Blacks in the US. The following are the Specific Aims: 1) To enhance diversity by providing professional development, education and scientific training, to strengthen health disparities research, skills and competencies among underrepresented and underserved early stage investigators and students. 2) To facilitate knowledge exchange of the science of cancer among African-descent populations, and increase research development and the coordination of research studies in Black populations. 3) To promote health equity by providing scientifically rigorous, and clinically and culturally informed research for greater community benefit in order to improve knowledge, awareness of cancer risk, strategies for cancer risk reduction and prevention.

项目概要 非洲-加勒比癌症联盟 (AC3) 是福克斯蔡斯癌症中心的一个全球肿瘤学项目 并通过解决涉及非裔美国人、加勒比海地区和非洲人的癌症差异发挥独特的作用 美国（U.S.）的移民及其原籍国的移民。 AC3 会员资格是跨- 学科（基础和人口科学研究人员、临床医生和癌症倡导者），由三部分组成 互联网络（美国、加勒比海和非洲）。我们 2023 年的会议主题：“从社区到分子 通过持续护理促进公平结果的早期筛查和诊断方法 “非洲裔人群中的癌症”反映了我们成员的跨学科构成。 此外，正如我们在之前的会议中取得的成绩一样，我们的 2023 年会议组委会、发言人和 观众将充分体现我们成员的多样性。在美国和世界范围内，癌症杀死了更多的黑人 高于任何其他种族/族裔群体。大量癌症过早死亡也发生在以黑人为主的人群中 撒哈拉以南非洲和加勒比地区的国家。黑人癌症研究仍然深入 不仅美国缺乏，非洲和加勒比地区黑人占主导地位的国家也缺乏。数量 非洲和加勒比地区的生物医学研究出版物正在增加，但差距仍然存在 研究文章集中于癌症。黑人科学家在 NCI 资助中的代表性也严重不足 收件人。因此，一支由训练有素的黑人科学家组成的国际骨干队伍增加了急需的多样性 全球癌症研究人员中。考虑到美国黑人人口的多样性，癌症研究 加勒比和非洲具有包容性，对于解决美国的癌症差异也至关重要。 研究方法在美国将是最有益的，因为这些研究对于提供信息和改进至关重要 对所有美国黑人进行癌症干预、治疗和预防。 AC3 科学与培训 因此，这次会议是合理的、及时的、有益的。我们以癌症为重点的培训、科学交流和 合作规划研讨会将有利于 AC3 加速癌症研究、推进 黑人科学家的职业生涯，并提供创新机会来研究影响黑人的癌症差异 在美国。具体目标如下： 1) 通过提供专业发展来增强多样性， 教育和科学培训，以加强健康差异研究、技能和能力 早期研究人员和学生代表性不足且服务不足。 2）促进知识交流 非洲人后裔癌症科学的发展，并加强研究发展和 协调黑人群体的研究。 3）通过科学提供促进健康公平 为了更大的社区利益，进行严格的、临床和文化方面的研究，以改善 知识、癌症风险意识、降低和预防癌症风险的策略。