The Gastrointestinal Epithelium Conference - Interface with the Outside World

胃肠上皮会议 - 与外界的接口

• 批准号: 10753753
• 负责人: Mark R Frey
• 金额: $ 4.2万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10753753
• 关键词: Area; Autophagocytosis; Basic Science; Biology; Biomedical Research; Cell Communication; Cells; Cellular biology; Clinical; Collaborations; Colon; Committee Members; Communication; Communities; Complement; Consultations; Data; Development; Developmental Biology; Digestive System Disorders; Diné Nation; Discipline; Disease; Drug Delivery Systems; Educational workshop; Ensure; Environment; Epithelium; Esophagus; Female; Friends; Funding; Future; Gastrointestinal Physiology; Gastrointestinal tract structure; Goals; Guanosine Triphosphate Phosphohydrolases; Health; Homeostasis; Hypoxia; In Vitro; Individual; Inflammation; Inflammatory Bowel Diseases; Intestines; Investigation; Laboratories; Length; Malignant Neoplasms; Mentorship; Metabolism; Methodology; Methods; Microbiology; Molecular; Molecular Biology; National Institute of Diabetes and Digestive and Kidney Diseases; Natural regeneration; Neurobiology; Oral; Parents; Participant; Physicians; Physiological; Process; Proliferating; Reagent; Request for Applications; Research; Research Personnel; Resolution; Role; Schedule; Science; Scientist; Sensory; Signal Transduction; Signaling Molecule; Site; Small Intestines; Stomach; Students; Systemic disease; Time; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Woman; bench to bedside; career; career development; cell motility; clinically significant; design; gastrointestinal; gastrointestinal epithelium; genetic manipulation; in vivo Model; injury and repair; innovation; insight; interest; intestinal barrier; lectures; live cell imaging; meetings; member; pathogen; posters; programs; response; response to injury; stem cell homeostasis; stem cells; symposium; trafficking

Project summary/abstract This application requests partial support for a FASEB Scientific Research Conference entitled “Gastrointestinal Epithelium: Interface with the Outside World” that is scheduled for September 17-21, 2023 in Steamboat Springs, CO. The meeting will convene a diverse group of speakers, including many women, underrepresented minorities, and young investigators, to discuss the biology of the gastrointestinal epithelium and its role in homeostasis and disease. The keynote presentations plus seven lecture sessions will address gastrointestinal stem cell homeostasis and plasticity in response to injury/disease; development and differentiation of the epithelium; injury repair, proliferation, and regeneration in the esophagus, stomach, small intestine, and colon; cell-cell interactions; host-pathogen interactions; intestinal barrier; hypoxia, inflammation and IBD; and cancer. Ample time will be set aside for discussions amongst participants, and the presentation of unpublished data will be prioritized. There will also be two poster sessions as well as several career development activities for early career investigators and trainees, as well as opportunities to promote the visibility of these individuals who represent the future of the field. We have assembled an innovative program with committed participation from leaders with diverse expertise within GI-related research fields. Overall, in an intimate and secluded setting that encourages informal interactions between scientists at all levels, we provide an innovative approach to the exchange of ideas and synthesis of science that will move the field of GI research forward. The conference will have high impact as the program spans basic science discovery to clinical significance for GI health and disease. It is therefore expected that the meeting will provide new insights not only into basic gastrointestinal physiology, neurobiology, developmental biology and microbiology, but also how to treat, and ultimately cure, a wide variety of digestive disease states.

项目概要/摘要 本申请要求部分支持FASEB科学研究会议，题为"胃肠道 Epithelium：与外部世界的接口"，定于2023年9月17日至21日在汽船 会议将召集一个多元化的发言者群体，包括许多妇女， 少数民族和年轻的研究人员，讨论胃肠道上皮的生物学及其在 稳态和疾病。主题演讲加上七个讲座将解决胃肠道 干细胞对损伤/疾病的稳态和可塑性; 上皮;食管、胃、小肠和结肠中的损伤修复、增殖和再生; 细胞-细胞相互作用;宿主-病原体相互作用;肠屏障;缺氧、炎症和IBD;以及癌症。 将留出充足的时间供与会者讨论，未发表的数据将 优先考虑。此外，还将举办两场海报展示会和几场职业发展活动， 职业调查员和受训人员，以及提高这些人的知名度的机会， 代表着这个领域的未来。我们已经组装了一个创新的计划，致力于参与， 在地理信息相关研究领域具有不同专业知识的领导者。总的来说，在一个亲密和隐蔽的环境中， 鼓励各级科学家之间的非正式互动，我们提供了一种创新的方法， 交流思想和科学的综合，将推动GI研究领域向前发展。会议将 具有很高的影响力，因为该计划涵盖了基础科学发现对GI健康的临床意义， 疾病因此，预计会议将提供新的见解，不仅对基本的胃肠 生理学，神经生物学，发育生物学和微生物学，以及如何治疗，并最终治愈， 各种各样的消化系统疾病状态。