2023 Forsyth Symposium: The Oral Microbiome: Past, Present, and Future

2023 年福赛斯研讨会：口腔微生物组：过去、现在和未来

• 批准号: 10753824
• 负责人: Jessica Leigh Mark Welch
• 金额: $ 0.7万
• 依托单位: ADA FORSYTH INSTITUTE, INC.
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10753824
• 关键词: Address; Applications Grants; Area; Bacteria; Basic Science; Biotechnology; Businesses; Capital; Chalk; Collaborations; Communication; Communities; Complex; Consensus; Disabled Persons; Disease; Ecology; Ecosystem; Educational workshop; Funding Agency; Funding Opportunities; Future; Generations; Genome; Goals; Growth; Health; Human; Individual; Industry; Knowledge; Malignant Neoplasms; Methods; Microbe; Microbiology; Minority Groups; Natural Immunity; Oral; Oral Microbiology; Oral cavity; Participant; Pathway interactions; Pattern; Personal Satisfaction; Persons; Play; Postdoctoral Fellow; Productivity; Research; Research Personnel; Role; Science; Scientist; Site; Students; Taxon; Therapeutic; Thinking; Woman; Work; acquired immunity; career; experience; experimental study; fundamental research; improved; innovation; marginalized population; member; microbial; microbial community; microbiome; microbiome research; novel strategies; oral bacteria; oral microbiome; posters; skills; symposium; transmission process

Abstract This R13 proposal seeks support for the 2023 Forsyth Symposium entitled “The Oral Microbiome: Past, Present, and Future,” which is proposed to take place at the Forsyth Institute on September 14-15, 2023, with a pre-conference workshop on presentation skills for trainees on September 13. The overall objectives of the symposium are to catalyze innovative thinking about areas where focused basic research on the oral microbiome will lead to improvements in human health; to promote collaboration among researchers using new approaches to advance the field of oral microbial ecology; and to honor and celebrate the pioneering work of Floyd Dewhirst and Bruce Paster on the oral microbiome, to transmit their knowledge and inspire a younger generation to continue their legacy of innovative science. An important goal is to provide the opportunity for trainees to interact with experts in the field and to encourage full participation of persons who are traditionally under-represented in science, including women, members of minority groups, and persons with disabilities. The symposium will include poster presentations by attendees and talks by Susan Bullman, Otto Cordero, Katherine Lemon, Tami Lieberman, Dennis Mangan, Dianne Newman, Frank Nichols, Jessica Scoffield, and William Wade. Scientific questions that will be addressed by the symposium include: what are the rules governing colonization of microbes at different sites within the mouth and what governs whether oral microbes colonize elsewhere in the body? How can the study of both oral and non-oral microbial communities illuminate oral microbial ecology? How do oral bacteria influence systemic health and disease? The symposium will also seek to bring together academic scientists with leaders from industry and venture capital, to brainstorm about what foundational experiments could lay the groundwork for therapeutic manipulation of the oral microbiome. If this conference succeeds as intended, it will enable individual investigators to form new high-quality collaborations and develop innovative grant proposals to carry out fundamental research that will elucidate the mechanisms and consequences of oral microbiome colonization, taxon-taxon interaction, and the systemic effects of oral microbiomes. Even more significantly, we hope that this conference will inspire and support new funding opportunity announcements by funding agencies, and new collaborations between business and academic researchers to drive innovation in oral microbiome research and its contribution to overall human health and well-being.

摘要 这份R13提案寻求对2023年福赛斯研讨会的支持，该研讨会的标题是：口腔微生物组：过去， 《现在与未来》计划于2023年9月14日至15日在福赛斯研究所举行， 九月十三日为学员举办讲解技巧的会前工作坊。 研讨会旨在促进对口腔基础研究领域的创新思维 微生物组将改善人类健康；促进研究人员之间的合作，使用新的 推进口腔微生物生态学领域的方法；并表彰和庆祝 弗洛伊德·德惠斯特和布鲁斯·帕斯特在口腔微生物组上，传递他们的知识，激励年轻的 一代人继续他们的创新科学遗产。一个重要的目标是为 受训人员与该领域的专家互动，并鼓励传统上 在科学界代表性不足，包括妇女、少数群体成员和残疾人。 研讨会将包括与会者的海报演示和苏珊·布尔曼、奥托·科德罗、 凯瑟琳·莱蒙、塔米·利伯曼、丹尼斯·曼根、黛安·纽曼、弗兰克·尼科尔斯、杰西卡·斯科菲尔德和 威廉·韦德。研讨会将讨论的科学问题包括：规则是什么 控制微生物在口腔内不同部位的定植，以及是什么控制了口腔微生物 在身体的其他地方定居吗？对口腔和非口腔微生物群落的研究如何说明 口腔微生物生态学？口腔细菌如何影响全身健康和疾病？研讨会还将 寻求将学术科学家与来自行业和风险资本的领导者聚集在一起，集思广益，讨论 哪些基础性实验可以为口腔微生物群的治疗操作奠定基础。如果 本次大会如期成功，它将使个别侦查员形成新的高素质 合作和开发创新的拨款建议，以开展基础研究，以阐明 口腔微生物群定植的机制和后果，分类群-分类群相互作用，以及系统 口腔微生物群的影响。更重要的是，我们希望本次会议将激励和支持新的 资助机构发布的资助机会公告，以及企业和 学术研究人员推动口腔微生物组研究创新及其对全人类的贡献 健康和幸福。