2023 Forsyth Symposium: The Oral Microbiome: Past, Present, and Future

2023 年福赛斯研讨会：口腔微生物组：过去、现在和未来

• 批准号: 10753824
• 负责人: Jessica Leigh Mark Welch
• 金额: $ 0.7万
• 依托单位: ADA FORSYTH INSTITUTE, INC.
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10753824
• 关键词: Address; Applications Grants; Area; Bacteria; Basic Science; Biotechnology; Businesses; Capital; Chalk; Collaborations; Communication; Communities; Complex; Consensus; Disabled Persons; Disease; Ecology; Ecosystem; Educational workshop; Funding Agency; Funding Opportunities; Future; Generations; Genome; Goals; Growth; Health; Human; Individual; Industry; Knowledge; Malignant Neoplasms; Methods; Microbe; Microbiology; Minority Groups; Natural Immunity; Oral; Oral Microbiology; Oral cavity; Participant; Pathway interactions; Pattern; Personal Satisfaction; Persons; Play; Postdoctoral Fellow; Productivity; Research; Research Personnel; Role; Science; Scientist; Site; Students; Taxon; Therapeutic; Thinking; Woman; Work; acquired immunity; career; experience; experimental study; fundamental research; improved; innovation; marginalized population; member; microbial; microbial community; microbiome; microbiome research; novel strategies; oral bacteria; oral microbiome; posters; skills; symposium; transmission process

Abstract This R13 proposal seeks support for the 2023 Forsyth Symposium entitled “The Oral Microbiome: Past, Present, and Future,” which is proposed to take place at the Forsyth Institute on September 14-15, 2023, with a pre-conference workshop on presentation skills for trainees on September 13. The overall objectives of the symposium are to catalyze innovative thinking about areas where focused basic research on the oral microbiome will lead to improvements in human health; to promote collaboration among researchers using new approaches to advance the field of oral microbial ecology; and to honor and celebrate the pioneering work of Floyd Dewhirst and Bruce Paster on the oral microbiome, to transmit their knowledge and inspire a younger generation to continue their legacy of innovative science. An important goal is to provide the opportunity for trainees to interact with experts in the field and to encourage full participation of persons who are traditionally under-represented in science, including women, members of minority groups, and persons with disabilities. The symposium will include poster presentations by attendees and talks by Susan Bullman, Otto Cordero, Katherine Lemon, Tami Lieberman, Dennis Mangan, Dianne Newman, Frank Nichols, Jessica Scoffield, and William Wade. Scientific questions that will be addressed by the symposium include: what are the rules governing colonization of microbes at different sites within the mouth and what governs whether oral microbes colonize elsewhere in the body? How can the study of both oral and non-oral microbial communities illuminate oral microbial ecology? How do oral bacteria influence systemic health and disease? The symposium will also seek to bring together academic scientists with leaders from industry and venture capital, to brainstorm about what foundational experiments could lay the groundwork for therapeutic manipulation of the oral microbiome. If this conference succeeds as intended, it will enable individual investigators to form new high-quality collaborations and develop innovative grant proposals to carry out fundamental research that will elucidate the mechanisms and consequences of oral microbiome colonization, taxon-taxon interaction, and the systemic effects of oral microbiomes. Even more significantly, we hope that this conference will inspire and support new funding opportunity announcements by funding agencies, and new collaborations between business and academic researchers to drive innovation in oral microbiome research and its contribution to overall human health and well-being.

摘要 这项R13提案寻求对2023年福赛斯研讨会的支持，该研讨会题为“口腔微生物组：过去， 现在，和未来，”这是建议发生在福赛斯研究所于2023年9月14日至15日，与 九月十三日为学员举办研讨会前工作坊，介绍演讲技巧。的总体目标 研讨会是催化创新思维的领域，重点是基础研究的口头 微生物组将导致人类健康的改善;促进研究人员之间的合作， 推进口腔微生物生态学领域的方法;并荣誉和庆祝的开创性工作， 弗洛伊德Dewhirst和布鲁斯帕斯特对口腔微生物组，传播他们的知识，并激励年轻人 这一代人继续他们的创新科学遗产。一个重要的目标是提供机会， 培训人员与该领域的专家进行互动，并鼓励传统上 科学领域的代表性不足，包括妇女、少数群体成员和残疾人。 研讨会将包括与会者的海报介绍和苏珊布尔曼，奥托科尔德罗， 凯瑟琳柠檬，塔米利伯曼，丹尼斯曼根，黛安纽曼，弗兰克尼科尔斯，杰西卡斯科菲尔德，和 威廉·韦德研讨会将讨论的科学问题包括： 控制口腔内不同部位微生物的定植， 在身体的其他地方定居口腔和非口腔微生物群落的研究如何阐明 口腔微生物生态学口腔细菌如何影响全身健康和疾病？研讨会还将 寻求将学术科学家与来自行业和风险投资的领导者聚集在一起，集思广益， 哪些基础实验可以为口腔微生物组的治疗操作奠定基础。如果 本次会议成功的预期，它将使个人研究人员形成新的高质量的 合作，并制定创新的赠款建议，以开展基础研究，将阐明 口腔微生物组定植、分类群-分类群相互作用和系统性 口腔微生物的影响。更重要的是，我们希望这次会议将激励和支持新的 融资机构的融资机会公告，以及企业和 学术研究人员推动口腔微生物组研究的创新及其对人类整体健康的贡献 健康和福祉。