Improving Survey/Cognitive Completions and Home Examination Successes in Wave VI of Add Health

项目摘要 在具有国家代表性的纵向研究中实现高同意和应答率是一项紧迫的任务 科学问题。全国青少年至成人健康纵向研究(Add Health)第六波-- 由基于网络的调查和认知功能评估(样本1)组成，基于面对面的 调查和认知、身体和感觉功能评估(样本2)，以及基于血液的家庭 样品1和样品2的检验--现已在现场进行。在过去的六个月里，我们派出了 作为样本1的一部分，我们在一个州进行了基于网络的调查和认知评估。此外，我们还推出了 2022年6月的家庭检查，我们正在采集血液来测试AD/ADRD的几个风险标记， 包括神经退行性变和炎症。这一试点在两个非常重要的方面进行得相当顺利。第一, 我们的实地考察过程运行良好。第二，我们正在接收的数据，既来自基于网络的 具有认知评估的调查和将用于测试AD/ADRD生物标记物的生物样本， 都是高质量的。同时，从我们的试点实地调查也已经清楚地表明，实现我们的调查 答复率目标和我们的家庭考试答复率目标将是非常具有挑战性的。这可能是在 部分原因是与新冠肺炎大流行有关的持续实地考察障碍；两极分化的社会和政治 国家的背景也可能是一个问题，尽管这两个因素都很难确定。但 还有一些关键的特定于研究的挑战，其中一些是我们提出这项研究时没有预料到的， 这使得我们的调查应答率目标和我们的家庭考试应答率目标的实现尤为重要 很难。这包括受访者的年龄范围和极其忙碌的生活(40-49岁)，越长- 我们的调查和认知评估工具的时间比预期的长(特别是对于我们的面对面 样本2调查)，以及达到我们受教育程度较低和种族/少数民族样本的具体挑战 会员。鉴于Add Health的巨大科学潜力，特别是考虑到种族/民族和 社会经济多样性、年龄范围和参与者的总体健康状况不佳，增加了对方法的投资 需要更多的同意和参与。为应对上述挑战和机遇， 本附录的具体目标是：1)实现最高的基于网络和认知功能的调查 第六波样本1中可能的答复率，特别是在受教育程度较低和少数族裔的受访者中， 通过三个新的战略，我们将采取。2)实现最高的面对面调查回复率 在第六波的样本2中有可能，特别是在受教育程度较低和少数群体的受访者中，通过 我们将做出两项关键的调整。3)实现尽可能高的上门考试完成率 健康浪潮六，特别是在受教育程度较低和少数群体的受访者中。这将涉及有针对性的 努力实现更高的家庭考试同意率和更高的家庭完成率 一旦答复者同意，即可进行检查。

Project Summary Achieving high consent and response rates in nationally-representative longitudinal studies is a pressing scientific issue. Wave VI of the National Longitudinal Study of Adolescent to Adult Health (Add Health) – consisting of a web-based survey and cognitive functioning assessment (Sample 1), an in-person based survey and cognitive, physical, and sensory functioning assessments (Sample 2), and a blood-based home examination for both Sample 1 and Sample 2 – is now in the field. Over the last six months, we have fielded our web-based survey and cognitive assessment in one state as part of Sample 1. In addition, we launched our home exam in June 2022, where we are collecting blood to test for several risk markers for AD/ADRD, including neurodegeneration and inflammation. This pilot has gone quite well in two very important ways. First, our fieldwork processes are working well. Second, the data that we are receiving, both from the web-based survey with cognitive assessment and the biological samples that will be used to test for AD/ADRD biomarkers, are of high quality. At the same time, it is also already clear from our pilot fieldwork that achieving our survey response rate goals and our home exam response rate goal is going to be very challenging. This may be in part due to ongoing fieldwork hurdles related to the Covid-19 pandemic; the polarized social and political context of the country is likely an issue as well, although both of these factors are difficult to ascertain. But there are also key study-specific challenges, some of which were unanticipated when we proposed the study, that make attainment of our survey response rate goals and our home exam response rate goal especially difficult. These include the age range and extremely busy lives of our respondents (ages 40-49), the longer- than-anticipated length of our survey and cognitive assessment instruments (especially for our in-person Sample 2 survey), and the specific challenges of reaching our less-educated and racial/ethnic minority sample members. Given the immense scientific potential of Add Health, particularly given the racial/ethnic and socioeconomic diversity, age range, and overall poor health of participants, enhanced investment in methods to increase consent and participation is needed. In response to the above challenges and opportunities, the Specific Aims of this supplement are: 1) To achieve the highest web-based and cognitive functioning survey response rate possible in Sample 1 of Wave VI, particularly among less-educated and minority respondents, through three fresh strategies we will employ. 2) To achieve the highest in-person-based survey response rate possible in Sample 2 of Wave VI, particularly among less-educated and minority group respondents, through two key adaptations we will be making. 3) To achieve the highest possible home exam completion rate in Add Health Wave VI, particularly among less-educated and minority group respondents. This will involve targeted efforts toward achieving both a higher consent rate for the home exam and a high completion rate for the home exam once respondents are consented.