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Mechanisms of mast cell influence on EAE disease course

Mechanisms of mast cell influence on EAE disease course
肥大细胞对EAE病程影响的机制
批准号：
7869508
负责人：
Melissa A Brown
金额：
$26.65万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
项目状态：
已结题
起止时间：
2006-01-01 至 2011-08-31
来源：
https://reporter.nih.gov/project-details/7869508
关键词：
AffectAllergicAnimalsAntigensAutoimmune ProcessB-LymphocytesBlood - brain barrier anatomyBlood VesselsBone MarrowBreedingCD4 Positive T LymphocytesCD8B1 geneCell Surface ProteinsCell physiologyCellsDendritic CellsDiseaseDisease susceptibilityEncephalomyelitisEpitopesEventExhibitsExperimental Autoimmune EncephalomyelitisFaceFlow CytometryFrequenciesGenerationsGenesHistamineHistamine ReleaseHomingImmunizationInflammatoryInterleukin-10Interleukin-4LeadLittle&aposs DiseaseLymphocyteLymphoidMediator of activation proteinMelissaMethodsModelingMouse StrainsMultiple SclerosisMusMyelinMyelin SheathNerveOrganOutcomePeptide HydrolasesPhasePhenotypePlayPopulationPredispositionPrintingProceduresProductionRegulationRelapseRelative (related person)Research PersonnelResearch Project GrantsRespiratory SystemRespiratory tract structureRodent ModelRoleSJL MouseSecondary toSeveritiesSiteSkinSpleenStagingStudy modelsSyndromeT cell regulationT-Cell ActivationT-LymphocyteTNFSF5 geneTestingTissuesTransgenic Organismsautoreactive T cellbasechemokinecytokineimmune functionlymph nodesmacrophagemast cellmigrationoligodendrocyte-myelin glycoproteinprogramsreceptorreconstitutionresponserestorationtrafficking

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Distinct mast cell responses in male and female SJL mice underlie sex dimorphic EAE susceptibility
Mechanisms Regulating Reduced c-Kit-Dependent EAE Susceptibility in Male SJL Mice
Mechanisms Regulating Reduced c-Kit-Dependent EAE Susceptibility in Male SJL Mice
Ikaros in mast vs. basophil lineage choice
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