Ecological Validity of PROMIS Instruments

PROMIS 仪器的生态有效性

• 批准号: 7944027
• 负责人: Joan E Broderick
• 金额: $ 144.26万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7944027
• 关键词: Address; Affect; Calculi; Clinical; Cognitive; Computer Assisted; Computers; Data; Degenerative polyarthritis; Evaluation; Face; Future; General Population; Health; Information Systems; Infusion procedures; Interview; Measurement; Measures; Medical; Medical Research; Medicine; Memory impairment; Modeling; Monitor; Nature; Operative Surgical Procedures; Outcomes Research; Participant; Patient Outcomes Assessments; Patient Self-Report; Patients; Pattern; Procedures; Protocols documentation; Psychometrics; Reporting; Research; Sampling; Science; Source; Sum; Symptoms; Testing; Theoretical model; Time; United States National Institutes of Health; Validation; Variant; base; chemotherapy; clinical practice; experience; heuristics; improved; innovation; insight; instrument; public health relevance; validation studies

DESCRIPTION (provided by applicant): Patient Reported Outcomes (PROs) are a necessary component of medical research and practice. The NIH- sponsored Patient-Reported Outcome Measurement Information System (PROMIS) has developed item banks and scales for several domains of symptoms and functioning, and these assessments are ready for validation. Ecological validity is an emerging and innovative approach to measurement validation. It is based on the premise that assessment scale scores using reporting periods of several days or more should have a high level of correspondence with ratings of that experience that are made on a dally or more frequent basis for the same reporting period. Good cortespondence indicates that the recall measure is not seriously compromised by memory deficits or other recall biases. This application proposes three major aims: to provide evidence of ecological and known-group validity of the PROMIS scales; to provide evidence of the responsiveness of the scales to change across time; and, to test a comprehensive theoretical model of 7-day recall in PROs. Study participants will complete weekly computer-assisted (CAT) PROMIS scales of the several domains and will monitor symptoms daily (to provide ecologically valid information) across a 4-week protocol. Five samples have been selected to provide variability in mean levels of the PROMIS scales (e.g., general population vs. osteoarthritis) and to provide patterns of change in symptoms over the 28-days (e.g., symptom shifts following chemotherapy or surgery). Second, the ability of PROMIS scales to track expected patterns of within-group change that correspond to changes captured by daily ratings will comprise a strong test of PROMIS scales' responsiveness to change. A comprehensive theoretical model of factors (cognitive heuristics) that influence recall ratings will also be tested. This research will provide a unique and important form of validation of PROMIS scales. The ability to probe the "meaning" of recall ratings will also make important contributions to the science of self-report and inform clinical Interpretation of PROs. PUBLIC HEALTH RELEVANCE: Patient reported outcomes (PROs) of symptoms and functioning are central to the medical research enterprise and to clinical practice. The newly developed PROMIS instruments are a major step in improving measurement of PROs. This study will provide information about the validity of the PROMIS instruments. Improved PROs will enhance our ability to assess health in the general population and evaluate new medicines and treatments.

描述（由申请人提供）：患者报告结局（PRO）是医学研究和实践的必要组成部分。NIH赞助的患者报告结局测量信息系统（PROMIS）已经为几个症状和功能领域开发了项目库和量表，这些评估已经准备好进行验证。生态有效性是一种新兴的和创新的方法来测量验证。其依据的前提是，使用几天或更长时间报告期的评估量表分数应与同一报告期每天或更频繁地对该经历进行的评级高度一致。良好的一致性表明回忆测量不会受到记忆缺陷或其他回忆偏差的严重影响。该应用程序提出了三个主要目标：提供证据的生态和已知组的有效性的PROMIS规模，提供证据的反应规模的变化，随着时间的推移;并且，在本发明中，测试PRO中7天回忆的综合理论模型。研究参与者将完成几个领域的每周计算机辅助（CAT）PROMIS量表，并将每天监测症状（以提供生态有效信息）。选择了五个样本，以提供PROMIS量表平均水平的变异性（例如，一般人群与骨关节炎）并提供28天内症状变化的模式（例如，化疗或手术后的症状变化）。第二，PROMIS量表跟踪与每日评级所反映的变化相对应的组内变化的预期模式的能力，将构成对PROMIS量表对变化的反应能力的有力检验。一个全面的理论模型的因素（认知能力），影响回忆率也将进行测试。这项研究将提供一个独特的和重要的PROMIS量表的验证形式。探索回忆评级的“意义”的能力也将对自我报告的科学做出重要贡献，并为临床解释提供信息。公共卫生相关性：患者报告的症状和功能结局（PRO）对医学研究企业和临床实践至关重要。新开发的PROMIS工具是改善PRO测量的重要一步。本研究将提供有关PROMIS工具有效性的信息。改进的PRO将提高我们评估普通人群健康状况和评估新药物和治疗方法的能力。

项目成果

Validity and reliability of patient-reported outcomes measurement information system instruments in osteoarthritis.

• DOI: 10.1002/acr.22025
• 发表时间: 2013-10
• 期刊: ARTHRITIS CARE & RESEARCH
• 影响因子: 4.7
• 作者: Broderick, Joan E.;Schneider, Stefan;Junghaenel, Doerte U.;Schwartz, Joseph E.;Stone, Arthur A.
• 通讯作者: Stone, Arthur A.