ARDS - EDEN Protocol

ARDS - EDEN 协议

• 批准号: 7824227
• 负责人: Rolf D Hubmayr
• 金额: $ 17.41万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2012-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7824227
• 关键词: ARDS; EDEN; Protocol

¿ Objectives: 1. To assess the safety and efficacy of initial trophic enteral feeding followed by advancement to full-calorie enteral feeding vs. initial advancement to full-calorie enteral feeding management strategies in reducing mortality and morbidity in patients with ALI or ARDS ¿ Hypotheses: 1. Initial trophic feeding followed by full-calorie enteral feeding will improve clinical outcomes (specifically increase the number of ventilator-free days to day 28 and decrease the 60-day, hospital mortality) in patients with ALI or ARDS by reducing systemic inflammation and the number of feeding complications as compared to early, full-calorie enteral feeding.

？目标： 1.评估在ALI或ARDS患者中，先进行营养肠内喂养，然后进行全热量肠内喂养与最初进行全热量肠内喂养相比，在降低死亡率和发病率方面的安全性和有效性。 ？假设： 1.与早期的全卡路里肠内喂养相比，通过减少全身炎症和喂养并发症的数量，最初的营养喂养和全热量肠内喂养将改善ALI或ARDS患者的临床结果(特别是将无呼吸机天数增加到第28天，并降低60天的住院死亡率)。