BONE DENSITY IN CHILDHOOD STUDY - CLINICAL CENTER

儿童骨密度研究(BMDCS)的目的是获得考虑骨骼成熟、骨大小和体积、身体大小和青春期阶段的标准参考骨密度指标。这些数据将作为非常有价值的儿科标准骨密度数据库。预计它将成为儿科医生研究、诊断和治疗影响骨积累的疾病儿童的基本参考。临床中心和数据协调中心的六份合同于2001年8月1日授予。这五个学术临床中心都遵循共同的纵向观察方案，包括基线和连续的三次年度评估，包括双X射线吸收测量(DXA)和骨龄X射线，这是一种确定其青春期状态、身高、体重和体重指数(BMI)的体检。此外，三个网站正在对部分儿童进行CT或pQCT扫描。每年从每个儿童那里获得与骨骼健康有关的信息，如饮食和锻炼。骨龄X光和DXA扫描集中解释。2002年7月在五个临床中心开始招募，截至2003年11月1日，招收了1554名6-16岁的儿童，包括男女和所有种族群体。

The purpose of the bone mineral density in childhood study (BMDCS) is to obtain standard reference bone mineral density measures taking into consideration skeletal maturation, bone size and volume, body size, and pubertal stage. These data will serve as an extremely valuable standard pediatric BMD database. It is anticipated to become the essential reference that will enable pediatricians to study, diagnose, and treat children with disorders affecting bone accrual. The six contracts for the Clinical Centers and the Data Coordinating Center were awarded on August 1, 2001. The five academic clinical centers all adhere to a common longitudinal observational protocol involving a baseline and three consecutive annual evaluations, including dual x-ray absorptiometry (DXA) and bone age x-ray, a physical exam to determine their pubertal status, stadiometer height, weight, and body mass index (BMI). Additionally, three sites are performing CT or pQCT scans on a subset of children. Information relating to bone health such as diet and exercise is obtained from each child annually. The bone age x-ray and DXA scans are interpreted centrally. Recruitment commenced in July 2002 at five Clinical Centers and resulted in the enrollment by November 1, 2003 of 1554 children from 6-16 years old of both genders and all racial groups.