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Immunopathogenesis of ANCA Disease

Immunopathogenesis of ANCA Disease
ANCA 疾病的免疫发病机制
批准号：
8032809
负责人：
GLORIA A PRESTON
金额：
$34.9万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8032809
关键词：
129 MouseAffectAfrican AmericanAllelesAmericanAnimal ModelAttentionAutoantibodiesAutoantigensAutoimmune DiseasesAutoimmunityBiologyBloodBone Marrow CellsCandidate Disease GeneCaringCellsCessation of lifeClinicalDiagnosisDiseaseDisease susceptibilityEZH2 geneEnzymesEpigenetic ProcessEtiologyFutureGene ExpressionGene SilencingGene-ModifiedGenesGeneticGenetic PolymorphismGenetic TranscriptionGenomeGenotypeGoalsGranulomatousHaplotypesHistonesHumanHuman BiologyImmature BoneImmunosuppressive AgentsInfectionInvestigationLearningLeukocytesLinkLongevityLungMalignant NeoplasmsMethylationMusNeutrophil ActivationNucleotidesOdds RatioOnset of illnessOutcomePRTN3 genePathologicPatientsPeripheralPhenotypeProductionQuantitative Trait LociReactive Oxygen SpeciesRegulationResearchSubgroupTestingTherapeuticTimeTo autoantigenTranscriptUp-Regulationbasecohortdisease phenotypedisorder controlepigenomicsgene discoverygenome wide association studyhistone methyltransferasehistone modificationmouse genomemouse modelneutrophilnoveloutcome forecastpatient populationresearch studysystemic autoimmune diseasetheoriestherapeutic target

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