PGE2 Receptor Function in Skin

皮肤中 PGE2 受体的功能

• 批准号: 7738953
• 负责人: Alice P Pentland
• 金额: $ 28.8万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-05-05 至 2010-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7738953
• 关键词: Acute; Affect; Affinity; Anti-Inflammatory Agents; Anti-inflammatory; Benefits and Risks; Cancer Model; Carcinogens; Cell physiology; Cells; Chemoprevention; Chemopreventive Agent; Chronic; Control Groups; Coupled; Data; Differentiation and Growth; Dinoprostone; EP4 receptor; Enzymes; Epidermis; Face; Glutathione; Growth; Human; Hypertrophy; Inbred HRS Mice; Incidence; Inflammatory; Interleukin-1; Link; Lipopolysaccharides; Malignant Neoplasms; Mediating; Modeling; Mus; Myocardial Infarction; Papilloma; Patients; Pharmaceutical Preparations; Printing; Prostaglandin E Receptor; Prostaglandin H2; Prostaglandin Receptor; Prostaglandin-Endoperoxide Synthase; Prostaglandins; Protein Isoforms; Receptor Signaling; Recording of previous events; Regulation; Relative (related person); Research Project Grants; Risk; Safety; Signal Transduction; Skin; Skin Cancer; Squamous cell carcinoma; Stimulus; Stroke; Sulfhydryl Compounds; Therapeutic; Therapeutic Agents; Translating; UV injury; Ultraviolet Rays; Work; cyclooxygenase 1; cyclooxygenase 2; inhibitor/antagonist; irradiation; keratinocyte; mouse PGE synthase 1; programs; prostaglandin EP2 receptor; receptor; receptor expression; receptor function; repaired; skin squamous cell carcinoma; therapeutic target; tumor progression; tumorigenesis

at the top of each printed page and each continuation page. RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page 1 Description,

在每个打印页和每个续页的顶部。 研究资助 目录 页码 首页1 产品描述：

项目成果

Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism.

• DOI: 10.1111/exd.12468
• 发表时间: 2014-08
• 期刊: Experimental dermatology
• 影响因子: 3.6
• 作者: Mantel A;Carpenter-Mendini A;VanBuskirk J;Pentland AP
• 通讯作者: Pentland AP