Novel Web-based Tools for Collaborative Community-Driven Genome Feature Annotatio

该项目的总体目标是开发一个灵活和 可扩展的基础设施，将允许整个社区 给定的有机体很容易对基因组注释做出贡献 进程。我们正在通过整合和显著 增强现有GMOD工具的功能：Apollo，用于 基因组特征注释的创建与特定的 DNA序列上的位置；分布式注释系统 (DAS)协议和支持交换的相关软件 研究人员之间在互联网上的注释；以及通用的 基因组浏览器(GBrowse)，用于显示基因组注释 交互式网页。我们正在将这些应用程序和 在它们的基础上创建基于Web的新型基础设施 将提供强大、易用的工具，实现协作、社区- 由更广泛的社区驱动的基因组特征注释 用户。

This project's overarching aim is to develop a flexible and extensible infrastructure that will allow the entire community of a given organism to easily contribute to the genome annotation process. We are doing this by integrating and significantly enhancing the functionality existing GMOD tools: Apollo, used for the creation of genomic feature annotations tied to specific locations on the DNA sequence; the Distributed Annotation System (DAS) protocol and associated software, which supports the exchange of annotations over the Internet between researchers; and Generic Genome Browser (GBrowse), used for displaying genome annotations on interactive Web pages. We are combining these applications and building on them to create a novel web-based infrastructure that will offer robust, easy-to-use tools for collaborative, community- driven genome feature annotation by a much broader community of users.