Substance Use and Risky Sex in Highly Vulnerable Populations

高危人群中的药物使用和危险性行为

• 批准号: 7923084
• 负责人: Natacha Marie De Genna
• 金额: $ 14.03万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7923084
• 关键词: 17 year old; Accounting; Adolescence; Adolescent; Adult; Adverse event; African American; Age; Aggressive behavior; Alcohol or Other Drugs use; Anger; Award; Barrier Contraception; Behavior; Behavioral; Birth; Borderline Personality Disorder; Characteristics; Childhood; Church; Clinical; Coitus; Collection; Contraceptive methods; Cross-Sectional Studies; Data; Data Analyses; Development; Diagnosis; Drug usage; Emotional; Environment; Epidemiology; Event; Faculty; Family; Funding; Gender; Goals; Gravidity; HIV; HIV Seropositivity; Impulsivity; Individual; Injecting drug user; Knowledge; Learning; Location; Longitudinal Studies; Measures; Mediating; Mediation; Methods; Mothers; Multiple Partners; Neighborhoods; Outcome; Personality; Pilot Projects; Population; Pregnancy; Prevalence; Prevention program; Principal Investigator; Psychiatry; Psychologist; Race; Recording of previous events; Reporting; Reproductive Health; Research; Research Methodology; Research Personnel; Risk; Risk Behaviors; Risk Factors; Risk-Taking; Role; Sampling; Schools; Sex Behavior; Sexual Partners; Sexually Transmitted Diseases; Substance Use Disorder; Supervision; Symptoms; Testing; Training; Training Activity; United States National Institutes of Health; Universities; Unplanned pregnancy; Unsafe Sex; Urine; Vulnerable Populations; Woman; Youth; adolescent offspring; adverse outcome; base; career; career development; cohort; experience; health disparity; high risk; high risk sexual behavior; medical schools; meetings; men who have sex with men; offspring; population health; post-doctoral training; pregnant; programs; public health relevance; reproductive; sex; sex risk; sexually active; skills; statistics; teenage mother; unintended pregnancy

DESCRIPTION (provided by applicant): The proposed project will help me develop the skills and expertise necessary to establish an independent research career focused on the role of substance use in sexual risk-taking behavior and associated adverse reproductive outcomes, especially sexually transmitted infections (STIs). To achieve this goal, I will supplement my graduate training as a developmental psychologist and postdoctoral training in epidemiology with training in sexual risk behavior in vulnerable populations, health disparities associated with race, and career development in longitudinal research methodology. Complementary to these training activities, I propose: 1) secondary data analyses of sexual risk behavior and outcomes using data from an ongoing longitudinal study of the offspring of teenage mothers and a study of women with and without borderline personality disorder (BPD); 2) collection of new data on the offspring of teenage mothers during a 16-year assessment and; 3) a new pilot study of common STIs in this sample (offspring of teenage mothers). The proposed research will form the basis for an R01 application in the third year of the award period. My short term goals are to (1) increase knowledge about risk for STIs, including behavioral dysregulation that may underlie risky sex and risk factors associated with risky sex and associated outcomes, (2) learn new methods of measuring risk behavior and adverse reproductive outcomes, including clinical tests for STIs and event-level assessments, (3) learn more about health disparities associated with race, and (4) develop the research skills that will enable me to become an independent investigator and obtain NIH funding to support my research, specifically longitudinal data analyses. My long-term career goal is to understand the ecological setting for drug use and sexual risk behaviors in vulnerable populations, and how drug use may contribute to significantly higher rates of unintended pregnancies and STIs in African-American youth. The proposed career development training will take place at the Department of Psychiatry at the University of Pittsburgh School of Medicine. This department provides an outstanding environment for interdisciplinary training by highly collaborative faculty who are leading experts in their chosen fields. PUBLIC HEALTH RELEVANCE: The proposed research will help identify behavioral risk factors for sexually transmitted infections that are implicated in higher rates of HIV, especially among African-Americans. The results can be used to develop prevention programs aimed at reducing drug use and sexually transmitted infections among vulnerable adolescents and within psychiatric populations.

描述（由申请人提供）：拟议的项目将帮助我发展必要的技能和专业知识，以建立一个独立的研究职业生涯，重点是物质使用在性冒险行为和相关的不良生殖结果，特别是性传播感染（STI）的作用。为了实现这一目标，我将补充我的研究生培训作为一个发展心理学家和博士后培训流行病学与培训在弱势群体的性风险行为，与种族相关的健康差距，以及纵向研究方法的职业发展。作为这些培训活动的补充，我建议：1）使用正在进行的对青少年母亲后代的纵向研究和对患有和不患有边缘性人格障碍（BPD）的妇女的研究的数据，对性风险行为和结果进行二级数据分析; 2）在16年的评估期间收集关于青少年母亲后代的新数据; 3）对这一样本（少女母亲的后代）中常见的性传播感染进行新的试点研究。拟议的研究将构成R 01申请的基础，在奖励期的第三年。我的短期目标是（1）增加对性传播感染风险的了解，包括可能导致危险性行为的行为失调以及与危险性行为相关的风险因素和相关结果，（2）学习测量风险行为和不良生殖结果的新方法，包括性传播感染的临床测试和事件水平评估，（3）更多地了解与种族相关的健康差异，以及（4）发展研究技能，使我能够成为一名独立的调查员，并获得NIH的资金支持我的研究，特别是纵向数据分析。我的长期职业目标是了解弱势群体中药物使用和性风险行为的生态环境，以及药物使用如何导致非裔美国青年意外怀孕和性传播感染的发生率显着升高。拟议的职业发展培训将在匹兹堡大学医学院精神病学系进行。该部门提供了一个优秀的环境，由高度协作的教师谁是在他们所选择的领域的领先专家进行跨学科培训。公共卫生关系：这项拟议中的研究将有助于确定与艾滋病毒感染率较高有关的性传播感染的行为风险因素，特别是在非洲裔美国人中。研究结果可用于制定预防计划，旨在减少弱势青少年和精神病人群中的药物使用和性传播感染。