Optimisation of beta-lactam antibiotic therapy as a strategy to improve efficacy and combat the emergence of resistance

抗生素耐药性是一个全球卫生优先事项，它可能会危及现代医学的进步，使实践回到抗生素出现之前的时代。危重病人和免疫功能受损的患者是一个脆弱的群体，他们与感染作斗争，严重依赖挽救生命的抗生素。该项目旨在研究如何优化抗生素的功效，以防止耐药性的出现，并为未来保留其有效性。

Antibiotic resistance is a global health priority that threatens to compromise advances in modern medicine to return practices to the pre-antibiotic era. Critically ill and patients with impaired immune function represent a vulnerable group who struggle to fight infections and who rely heavily on lifesaving antibiotics. This project aims to investigate how the efficacy of antibiotics can be optimised to prevent the emergence of resistance and preserve their effectiveness for the future.