Simian Vaccine Evaluation Unit (SVEU)

西蒙疫苗评价股(SVEU)的主要职能如下： 1非人类灵长类动物的获取和检测(主要重点将是印度血统的恒河猴(Macaca Mulatta)、中国血统的猕猴或其他非人类灵长类物种，如猪尾猕猴(Macaca Nomestrina)、食蟹猴(Macaca Fascular Aris)、非洲绿猴(Cercocebus Atys)或狒狒。 2.非人类灵长类动物的收容和照料；动物记录的维护(提供无结核病的非人类灵长类动物，也未感染猴免疫缺陷病毒(SIV)、猴T细胞淋巴营养病毒(STLV)和猴D型逆转录病毒(SRV))。为了确认动物没有感染这些逆转录病毒，在购买和运输到SVEU设施之前，对非人类灵长类动物进行测试，以筛选这些病毒。此外，测试非人类灵长类动物是否存在B型疱疹病毒抗体，以便了解它们的血清状态。 3.协议开发 4.研究的进行 5.体外实验室免疫学和病毒学检测 6.物资的储存和运输 7.将SVEU研究方案、信息和数据输入DAIDS SVEU数据库

The major functions to be carried out by the Simian Vaccine Evaluation Units (SVEUs) are as follows: 1 Acquisition and testing of non-human primates (Primary emphasis will be on rhesus macaques (Macaca mulatta) of Indian origin, Chinese-origin macaques, or other nonhuman primate species, such as pig-tail macaques (Macaca nemestrina), cynomolgus monkeys (Macaca fascicularis), African green monkeys (Cercocebus atys), or baboons may be requested. 2. Housing and care of non-human primates; maintenance of animal records (Provide tuberculosis (TB)-free nonhuman primates that are also free of infection with simian immunodeficiency virus (SIV), simian T-cell lymphotrophic virus (STLV), and simian type D retrovirus (SRV). To confirm that animals are free from infection with these retroviruses, conduct testing of the nonhuman primates to screen for these viruses prior to purchase and shipment to the SVEU facility. In addition, test the nonhuman primates for the presence of antibodies to simian herpes B virus so that their serostatus is known. 3. Protocol Development 4. Conduct of Studies 5. In Vitro Laboratory Immunologic and Virologic Assays 6. Storage and shipment of materials 7. Entry of SVEU study protocols, information, and data into the DAIDS SVEU database