Simian Vaccine Evaluation Unit (SVEU)

猿猴疫苗评估中心 (SVEU)

• 批准号: 8152771
• 负责人: Phillip D Markham
• 金额: $ 522.97万
• 依托单位: ADVANCED BIOSCIENCE LABORATORIES, INC.
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-22 至 2013-06-21
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8152771
• 关键词: AIDS Vaccines; Advanced Development; Animals; Antibodies; Biological Assay; Caring; Cercocebus atys; Cercopithecine Herpesvirus 1; Cercopithecus pygerythrus; Chinese People; Contracts; Data; Databases; Development; Family suidae; Housing; Immunologics; Immunotherapy; In Vitro; Infection; Laboratories; Macaca; Macaca fascicularis; Macaca mulatta; Macaca nemestrina; Maintenance; Modality; National Institute of Allergy and Infectious Disease; Papio; Prevention; Protocols documentation; Records; Retroviridae; SIV; Tail; Testing; Tuberculosis; Type D Retrovirus; Virus; microbicide; nonhuman primate; protocol development; simian T cell lymphotrophic virus; vaccine evaluation

The major functions to be carried out by the Simian Vaccine Evaluation Units (SVEUs) are as follows: 1 Acquisition and testing of non-human primates (Primary emphasis will be on rhesus macaques (Macaca mulatta) of Indian origin, Chinese-origin macaques, or other nonhuman primate species, such as pig-tail macaques (Macaca nemestrina), cynomolgus monkeys (Macaca fascicularis), African green monkeys (Cercocebus atys), or baboons may be requested. 2. Housing and care of non-human primates; maintenance of animal records (Provide tuberculosis (TB)-free nonhuman primates that are also free of infection with simian immunodeficiency virus (SIV), simian T-cell lymphotrophic virus (STLV), and simian type D retrovirus (SRV). To confirm that animals are free from infection with these retroviruses, conduct testing of the nonhuman primates to screen for these viruses prior to purchase and shipment to the SVEU facility. In addition, test the nonhuman primates for the presence of antibodies to simian herpes B virus so that their serostatus is known. 3. Protocol Development 4. Conduct of Studies 5. In Vitro Laboratory Immunologic and Virologic Assays 6. Storage and shipment of materials 7. Entry of SVEU study protocols, information, and data into the DAIDS SVEU database

由猿猴疫苗评估单元（SVEU）执行的主要功能如下： 1 Acquisition and testing of non-human primates (Primary emphasis will be on rhesus macaques (Macaca mulatta) of Indian origin, Chinese-origin macaques, or other nonhuman primate species, such as pig-tail macaques (Macaca nemestrina), cynomolgus monkeys (Macaca fascicularis), African green monkeys (Cercocebus atys), or可以要求狒狒。 2。非人类灵长类动物的住房和护理；维持动物记录（提供结核病（TB）的非人类灵长类动物，这些灵长类动物也没有感染，这些灵长类动物也没有感染，simian免疫缺陷病毒（SIV），Simian T-Cell淋巴营养病毒（STLV）（STLV）和D型D型D型逆转录病毒（SRV），以确认这些动物在这些临床上进行筛选，以确认这些依从性，以确认这些动物的依从性。并运往SVEU设施。 3。协议开发 4。研究的行为 5。体外实验室免疫和病毒学测定 6。材料的存储和运输 7。将SVEU研究协议，信息和数据输入到daids SVEU数据库中