Advanced Technology QA Center

描述（由申请人提供）： 先进技术质量保证中心 我们的计划是利用国家现有质量保证 (QA) 计划的基础设施和优势，该计划由我们的先进技术 QA 联盟 (ATC) 组成，包括图像引导治疗中心 (ITC)、放射治疗肿瘤学组 (RTOG)、放射物理中心 (RPC) 和质量保证审查中心 (QARC)，以维护/开发先进的医疗信息学基础设施，为机构提供可以提交的环境，并且 QA 中心可以接收、共享和分析体积多模态成像/治疗计划/验证 (ITPV) 数字数据。具体来说，我们将 (1) 使用 ATC Method-1（现称为 QuASAR-1（质量保证提交、分析和审核-1）系统）维护/管理（并根据需要进行渐进式改进）先进技术（3DCRT、IMRT、SBRT 和近距离放射治疗）方案认证和病例数据、档案存储和远程 QA 审核流程的当前电子数据提交； (2) 开发新颖的基于网络的远程审查工具，以提高利用先进技术对方案进行高效和有效的审查。这些工具的设计基础设施将有助于未来协议流程的开发，例如图像引导放射治疗（IGRT）和适应性放射治疗（ART）。拟议的系统被称为QuASAR-2，采用模块化设计，以促进高效工具和子系统的开发，实现与现有软件标准的兼容性，包括癌症生物信息学网格（caBIG）和DICOM RT，并维护/开发可与合作小组的临床结果数据库链接的档案ITPV、认证/QA数据库； （3）协助合作团体制定和管理先进技术临床试验方案，包括（a）肿瘤/靶体积和危险器官的定义； (b) 资格认证要求和评价标准； (c) 电子数据提交要求/说明； (d) 质量保证审查程序； （4）作为全国临床试验合作团体和参与机构的教育资源，支持先进技术放射治疗临床试验。我们的 ATC QA 联盟方法将有助于避免服务/开发工作的重复，并促进所有合作组临床试验的统一认证/QA 标准的制定。

DESCRIPTION (provided by applicant): Advanced Technology QA Center Our plan is to capitalize on the infrastructure and strengths of the nation's existing quality assurance (QA) programs that comprise our Advanced Technology QA Consortium (ATC), including the Image-Guided Therapy Center (ITC), Radiation Therapy Oncology Group (RTOG), Radiological Physics Center (RPC), and the Quality Assurance Review Center (QARC) to maintain/develop an advanced medical informatics infrastructure that provides an environment in which institutions can submit, and QA Centers can receive, share, and analyze volumetric multimodality imaging/treatment planning/verification (ITPV) digital data. Specifically, we will (1) maintain/manage (and make incremental improvements as required to) the current electronic data submission of advanced technology (3DCRT, IMRT, SBRT, and brachytherapy) protocol credentialing and case data, archival storage, and remote QA review process utilizing ATC Method-1 (now referred to as the QuASAR-1 (Quality Assurance Submission, Analysis, and Review-1) system); (2) develop novel web-based remote-review tools that will enhance the efficient and effective review of protocols utilizing advanced technologies. The design infrastructure of these tools will assist the development of future protocol processes such as image-guided radiation therapy (IGRT) and adaptive radiation therapy (ART). The proposed system is referred to as QuASAR-2 and will be modular in design to promote efficient tools and subsystems development that achieve compatibility with existing software standards, including the Cancer Bioinformatics Grid (caBIG) and DICOM RT, and maintain/develop archival ITPV, credentialing/QA databases that can be linked with the cooperative group's clinical outcomes database; (3) assist cooperative groups in the development and management of advanced technology clinical trials protocols including (a) tumor/target volume and organ at risk definitions; (b) credentialing requirements and evaluation criteria; (c) electronic data submission requirements/instructions; (d) QA review procedures; and (4) serve as an educational resource to the nation's clinical trial cooperative groups and participating institutions for support of advanced technology radiation therapy clinical trials. Our ATC QA consortium approach will help avoid duplication of service/developmental efforts and promote development of uniform credentialing/QA criteria for clinical trials throughout all Cooperative Groups.