Translating Research into Systemic Interventions for Tobacco Cessation

将研究转化为戒烟的系统干预措施

• 批准号: 8044899
• 负责人: Dorothy Elinor Apollonio
• 金额: $ 16.42万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-13 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8044899
• 关键词: Accreditation; Acute; Address; Advocacy; Affect; Alcohols; Anecdotes; Archives; Award; Behavior Therapy; California; Cancer Etiology; Cessation of life; Clinical; Clinical Research; Communication; Complement; Continuing Education; Data; Disease; Drug abuse; Educational Intervention; Effectiveness; Ensure; Evidence Based Medicine; Focus Groups; General Population; Generations; Goals; Health Policy; Individual; Intervention; Interview; K-Series Research Career Programs; Knowledge; Lead; Licensing; Licensure; Literature; Malignant neoplasm of lung; Mental Health; Mentors; Online Systems; Outcome; Participant; Pharmacy facility; Play; Policies; Policy Research; Population; Population Policies; Positioning Attribute; Postdoctoral Fellow; Process; Public Health; Public Relations; Publishing; Qualitative Research; Regulation; Reporting; Research; Research Methodology; Research Personnel; Role; San Francisco; Science; Smoking; Source; Substance Abuse Treatment Centers; Surveys; Testing; Time; Tobacco; Tobacco Use Cessation; Tobacco use; Training; Training Activity; Translating; Translation Process; Translational Research; Translations; United States; Universities; Work; base; cancer risk; design; experience; follow-up; health disparity; improved; information gathering; member; news; professor; public health relevance; smoking cessation; standard of care; symposium; systematic review; systemic intervention; web site

DESCRIPTION (provided by applicant): This is the final submission of an application for a K07 award for Dr. Dorie Apollonio, an Assistant Professor at the University of California, San Francisco, who is establishing herself as a new translational researcher. Her proposal focuses on efforts to use clinical research to support the creation of state policies mandating that smoking cessation therapy be available to ADM populations in treatment. This award will provide Dr. Apollonio with support necessary to achieve the goal of becoming an independent translational researcher experienced with all steps of the research translation process-clinical research generation, aggregation, and finally, its use by policy intermediaries-advocacy groups and journalists-who communicate these findings to policymakers. To achieve this goal, Dr. Apollonio has assembled a group of advisors including two primary mentors, Dr. Lisa Bero, Professor of Clinical Pharmacy, an expert in the creation of systematic reviews and in evidence-based medicine, and Dr. Ruth Malone, an expert in tobacco use in ADM populations. In addition, three co-mentors will provide expertise specific to each set of training activities and their associated aim; Dr. Neal Benowitz will share his knowledge of how clinical research is conducted, Dr. Daniel Dohan, will communicate his experience with qualitative research methods, and Dr. Laura Schmidt will provide training in developing behavioral interventions. In addition, she will work with four collaborators: Dr. Steven Schroeder and Dr. Joseph Guydish, who have been active with organizations seeking to implement smoking cessation therapy in mental health and substance abuse treatment centers, and Dr. Lisa Schwartz and Dr. Steven Woloshin, who have experience designing and evaluating educational interventions. Although clinical research often identifies effective public health interventions, many such interventions are not enacted into policy, leading to unnecessary death and disease. This problem is particularly acute in research on tobacco use, the leading preventable cause of cancer deaths in the United States, which disproportionately affects ADM populations. Dr. Apollonio's proposal will: (Aim 1) assess the correspondence between research evidence and popular understanding of smoking cessation therapy in ADM populations; (Aim 2) determine the means by which clinical researchers and policy intermediaries communicate scientific research findings; and (Aim 3) design, pilot test and evaluate web-based educational interventions to encourage better communication between policy intermediaries and clinical researchers. This research will form the basis for an R01 application to refine and study the effectiveness of educational interventions as a means of improving research translation.

描述（由申请人提供）：这是Dorie Apollonio博士申请K 07奖的最后一次提交，Dorie Apollonio博士是加州大学旧金山分校弗朗西斯科的助理教授，她正在成为一名新的翻译研究人员。她的建议侧重于努力利用临床研究，以支持国家政策的制定，强制要求戒烟治疗可用于ADM人群的治疗。该奖项将为Apollonio博士提供必要的支持，以实现成为一名独立的翻译研究人员的目标，该研究人员经历了研究翻译过程的所有步骤-临床研究生成，聚合，最后，由政策中介机构-倡导团体和记者-将这些发现传达给政策制定者。为了实现这一目标，Apollonio博士召集了一组顾问，其中包括两名主要导师，临床药学教授丽莎贝罗博士，系统评价和循证医学方面的专家，以及ADM人群烟草使用方面的专家露丝马龙博士。此外，三位共同导师将提供针对每组培训活动及其相关目标的专业知识; Neal Benowitz博士将分享他如何进行临床研究的知识，丹尼尔Dohan博士将交流他使用定性研究方法的经验，Laura施密特博士将提供制定行为干预措施的培训。此外，她将与四位合作者合作：Steven Schroeder博士和Joseph Guydish博士，他们一直积极参与寻求在精神健康和药物滥用治疗中心实施戒烟治疗的组织，以及丽莎施瓦茨博士和Steven Woloshin博士，他们有设计和评估教育干预措施的经验。虽然临床研究往往能确定有效的公共卫生干预措施，但许多此类干预措施并未纳入政策，导致不必要的死亡和疾病。这个问题在对烟草使用的研究中尤为严重，烟草使用是美国癌症死亡的主要可预防原因，对ADM人群的影响不成比例。Apollonio博士的建议将：（目标1）评估研究证据与ADM人群戒烟治疗的普遍理解之间的对应关系;（目标2）确定临床研究人员和政策中介机构传达科学研究结果的方式;和（目标3）设计，试点测试和评估基于网络的教育干预措施，以鼓励政策中介机构和临床研究人员之间更好的沟通。这项研究将成为R 01应用程序的基础，以改进和研究教育干预措施的有效性，作为改善研究翻译的一种手段。