Renal Hemodynamics: Mechanisms to Understand Disease

肾脏血流动力学：了解疾病的机制

• 批准号: 7908575
• 负责人: Jeffrey L. Garvin
• 金额: $ 1.6万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7908575
• 关键词: Academy; Address; Area; Asia; Australia; Award; Biomedical Research; Blood Circulation; Clinical; Clinical Investigator; Diabetes Mellitus; Diabetic Nephropathy; Disease; Endothelin; Europe; Excretory function; Faculty; Female; Fostering; Functional disorder; Funding; Goals; Hypertension; Inflammatory; Kidney; Kidney Diseases; Kidney Failure; Metabolic syndrome; Minority; Nerve; New Zealand; North America; Obesity; Participant; Physiology; Process; Prostaglandins; Regulation; Renal Hypertension; Renal function; Renin; Research; Research Personnel; Rivers; Role; Schedule; Scientist; Sex Characteristics; Signal Transduction; Sodium; Sodium Chloride; Students; Time; Translating; Travel; Underrepresented Minority; Vascular Smooth Muscle; Vermont; Woman; abstracting; authority; base; career; design; glomerulosclerosis; hemodynamics; kidney vascular structure; meetings; multidisciplinary; novel; planetary Atmosphere; posters; programs; public health relevance; salt sensitive; symposium

DESCRIPTION (provided by applicant): The FASEB Summer Research Conference on "Renal Hemodynamics: Mechanisms to Understand Disease" is scheduled for June 20 through 25, 2010 at Vermont Academy, Saxtons River, VT. The meeting is held once every three years. It will provide a forum for multidisciplinary scientists to meet and openly discuss their most current research in an informal, casual, relaxed atmosphere. We have revised the format of the meeting to increase the amount of time for discussion and poster sessions which will foster more in-depth interactions especially between established and early career investigators. We will have special sessions highlighting the latest ongoing research of students, fellows and new investigators. Conference aims are: 1) to convene an internationally recognized multidisciplinary group of investigators to present and discuss current research findings in the area of renal hemodynamic mechanisms that are the cause or consequence of diseases including hypertension, diabetes, obesity, metabolic syndrome, glomerular sclerosis and nephropathy; 2) to promote the participation of early career investigators; and 3) to promote the participation of women and under-represented minorities. We will promote participation of early career investigators, women and minorities through targeted recruitment and travel awards. To this end, we have increased participation by these groups as invited speakers and session moderators over previous conferences. Specific topics to be covered include: novel issues in hypertension and diabetes; salt retention and renal damage in obesity; hypertension and renal damage in diabetic nephropathy; salt-sensitive hypertension; regulation of sodium excretion by renal nerves; the role of the medullary circulation in Na excretion; vascular smooth muscle signaling; causes and consequences of renal failure; inflammatory processes in the kidney; gender differences in renal function and hypertension; role of endothelin and NO in hypertension and renal function; recent advances in renin release; prostanoids in the kidney; and cross-talk between tubules and renal vessels. PUBLIC HEALTH RELEVANCE: The purpose of this application is to fund a conference entitled "Renal Hemodynamics: Mechanisms to Understand Disease" which will provide a forum for multidisciplinary scientists to meet and openly discuss their most current research in an informal atmosphere thus facilitating the transfer of information from basic researchers to clinical investigators. The program has been designed to foster in- depth interactions between established and early career investigators and to promote the participation of women and under-represented minorities through targeted recruitment and travel awards.

描述（由申请人提供）： FASEB 夏季研究会议“肾脏血流动力学：了解疾病的机制”定于 2010 年 6 月 20 日至 25 日在佛蒙特州萨克斯顿河佛蒙特学院举行。该会议每三年举行一次。它将为多学科科学家提供一个论坛，让他们在非正式、随意、轻松的氛围中会面并公开讨论他们最新的研究。我们修改了会议的形式，以增加讨论和海报会议的时间，这将促进更深入的互动，特别是在已建立的和早期职业研究者之间。我们将举办特别会议，重点介绍学生、研究员和新研究人员正在进行的最新研究。 会议的目标是： 1) 召集国际公认的多学科研究人员小组，介绍和讨论肾血流动力学机制领域的最新研究成果，肾血流动力学机制是高血压、糖尿病、肥胖、代谢综合征、肾小球硬化和肾病等疾病的原因或后果； 2）促进早期职业研究者的参与； 3) 促进妇女和代表性不足的少数群体的参与。我们将通过有针对性的招聘和旅行奖励来促进早期职业调查员、女性和少数族裔的参与。为此，与之前的会议相比，我们增加了这些团体作为特邀发言人和会议主持人的参与。 涵盖的具体主题包括：高血压和糖尿病的新问题；肥胖引起的盐潴留和肾损伤；糖尿病肾病中的高血压和肾损伤；盐敏感性高血压；肾神经对钠排泄的调节；髓质循环在钠排泄中的作用；血管平滑肌信号传导；肾衰竭的原因和后果；肾脏的炎症过程；肾功能和高血压的性别差异；内皮素和 NO 在高血压和肾功能中的作用；肾素释放的最新进展；肾脏中的前列腺素；以及肾小管和肾血管之间的串扰。公共健康相关性：本申请的目的是资助一个题为“肾脏血流动力学：了解疾病的机制”的会议，该会议将为多学科科学家提供一个论坛，让他们在非正式的氛围中会面并公开讨论他们最新的研究，从而促进信息从基础研究人员向临床研究人员的转移。该计划旨在促进已建立的调查员和早期职业调查员之间的深入互动，并通过有针对性的招募和旅行奖励来促进女性和代表性不足的少数群体的参与。