HOST AND TUMOR CELL IPLA2 IN OVARIAN CANC

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 宿主-肿瘤细胞相互作用已被认为是肿瘤发展的关键因素。我们已经表明，钙非依赖性磷脂酶A2（iPLA 2）是重要的调节细胞外溶血磷脂酸（LPA）水平在人上皮性卵巢癌（EOC）细胞。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Host-tumor cell interaction has been recognized as a critical factor for tumor development. We have shown that calcium-independent phospholipase A2 (iPLA2) is important for regulating extracellular lysophosphatidic acid (LPA) levels in human epithelial ovarian cancer (EOC) cells.