Bone Tissue Engineering and Regeneration: From Discovery to the Clinic

骨组织工程与再生：从发现到临床

• 批准号: 8062953
• 负责人: Regis J O'Keefe
• 金额: $ 2.51万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-05 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8062953
• 关键词: Address; Animals; Area; Arts; Biocompatible Materials; Biomechanics; Bone Regeneration; Bone Substitutes; Bone Tissue; Cells; Cellular biology; Clinic; Clinical; Clinical Immunology; Collaborations; Collection; Communities; Complex; Defect; Development; Discipline; Educational workshop; Engineering; Event; Fees; Florida; Funding; Funding Agency; Future; Gene Proteins; Goals; Government; Healed; Health; Human; Impaired wound healing; In Vitro; Individual; Industry; Journals; Knowledge; Laboratories; Lead; Minority; Molecular Biology; Musculoskeletal Diseases; Natural regeneration; Organ; Participant; Patient Care; Process; Publications; Publishing; Recommendation; Research; Research Personnel; Science; Scientific Advances and Accomplishments; Scientist; Seminal; Staging; Stem cells; Structure; Students; Technology; Tissue Engineering; Tissues; Translations; Transplantation; United States National Institutes of Health; Woman; Writing; bone; bone engineering; career development; clinical care; design; disorder prevention; effective therapy; healing; improved; interest; meetings; pre-clinical; publication formats; restoration; scaffold; symposium

DESCRIPTION (provided by applicant): A one-day workshop is proposed that is entitled "Bone Tissue Engineering and Regeneration: From Discovery to the Clinic" in Orlando, Florida on Sunday, December 5, 2010. The workshop goals are: i) to define the state of art in the field; ii) to identify those areas where scientific advances are necessary for improved translational treatments of bone defects and impaired healing, and iii) to develop an "action plan" that will influence future directions and enable advancement in the bone tissue engineering field. Specific Aim 1 is designed to provide a forum for clinicians, scientists, engineers, industry, and government representatives to discuss and define the progress, opportunities, and translational needs for advancing bone tissue engineering. The workshop has superb group of scientific participants, excellent representation by leading women and minority scientists, and inclusion of students and trainees. The presenters at this meeting will discuss the state of advancement of bone tissue engineering within an assigned sub-area of research. The focus will be on the challenges and opportunities of the field and the areas where collaboration and intersection with other disciplines is critical for advancement. Specific Aim 2 develops an "action plan" to positively influence the translation and future directions of the bone tissue engineering field. In Aim 2A the workshop will occur as at the initiation of the TERMIS-NA meeting in Orlando FL on December 5, 2010 to capitalize on the assembly of world experts in attendance. In Aim 2B the workshop will be designed to attract students and trainees to the event. In Aim 2C a publication strategy is designed so that the meeting content and summary of the recommendations can be widely disseminated.. In summary, the development of integrative, realistic and effective strategies for regenerating human bone is a critical and unsolved problem. The workshop will the body of knowledge currently present in the various fields related to bone regeneration and will identify key areas for clinical translation towards improved bone regeneration strategies.

描述（由申请人提供）：提议于2010年12月5日星期日在佛罗里达奥兰多举行为期一天的研讨会，题为“骨组织工程和再生：从发现到临床”。讲习班的目标是：i）定义该领域的最新技术水平; ii）确定那些需要科学进步来改善骨缺损和愈合受损的转化治疗的领域;以及iii）制定将影响未来方向并实现骨组织工程领域进步的“行动计划”。具体目标1旨在为临床医生，科学家，工程师，行业和政府代表提供一个论坛，以讨论和定义推进骨组织工程的进展，机会和转化需求。讲习班有一流的科学参与者，杰出的妇女和少数民族科学家的代表性，以及学生和受训人员的参与。在这次会议上的演讲者将讨论在指定的研究子领域内骨组织工程的进展状况。重点将是该领域的挑战和机遇，以及与其他学科的合作和交叉对进步至关重要的领域。具体目标2制定了一个“行动计划”，以积极影响骨组织工程领域的翻译和未来方向。在目标2A中，研讨会将于2010年12月5日在佛罗里达州奥兰多举行的TERMIS-NA会议开始时举行，以利用出席会议的世界专家的集会。在目标2B中，讲习班将旨在吸引学生和受训人员参加活动。在目标2C中，制定了一项出版战略，以便广泛传播会议内容和建议摘要。总之，开发综合的、现实的和有效的人类骨再生策略是一个关键的和未解决的问题。该研讨会将介绍目前与骨再生相关的各个领域的知识体系，并将确定临床翻译的关键领域，以改善骨再生策略。