Bone Tissue Engineering and Regeneration: From Discovery to the Clinic

骨组织工程与再生：从发现到临床

• 批准号: 8062953
• 负责人: Regis J O'Keefe
• 金额: $ 2.51万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-05 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8062953
• 关键词: Address; Animals; Area; Arts; Biocompatible Materials; Biomechanics; Bone Regeneration; Bone Substitutes; Bone Tissue; Cells; Cellular biology; Clinic; Clinical; Clinical Immunology; Collaborations; Collection; Communities; Complex; Defect; Development; Discipline; Educational workshop; Engineering; Event; Fees; Florida; Funding; Funding Agency; Future; Gene Proteins; Goals; Government; Healed; Health; Human; Impaired wound healing; In Vitro; Individual; Industry; Journals; Knowledge; Laboratories; Lead; Minority; Molecular Biology; Musculoskeletal Diseases; Natural regeneration; Organ; Participant; Patient Care; Process; Publications; Publishing; Recommendation; Research; Research Personnel; Science; Scientific Advances and Accomplishments; Scientist; Seminal; Staging; Stem cells; Structure; Students; Technology; Tissue Engineering; Tissues; Translations; Transplantation; United States National Institutes of Health; Woman; Writing; bone; bone engineering; career development; clinical care; design; disorder prevention; effective therapy; healing; improved; interest; meetings; pre-clinical; publication formats; restoration; scaffold; symposium

DESCRIPTION (provided by applicant): A one-day workshop is proposed that is entitled "Bone Tissue Engineering and Regeneration: From Discovery to the Clinic" in Orlando, Florida on Sunday, December 5, 2010. The workshop goals are: i) to define the state of art in the field; ii) to identify those areas where scientific advances are necessary for improved translational treatments of bone defects and impaired healing, and iii) to develop an "action plan" that will influence future directions and enable advancement in the bone tissue engineering field. Specific Aim 1 is designed to provide a forum for clinicians, scientists, engineers, industry, and government representatives to discuss and define the progress, opportunities, and translational needs for advancing bone tissue engineering. The workshop has superb group of scientific participants, excellent representation by leading women and minority scientists, and inclusion of students and trainees. The presenters at this meeting will discuss the state of advancement of bone tissue engineering within an assigned sub-area of research. The focus will be on the challenges and opportunities of the field and the areas where collaboration and intersection with other disciplines is critical for advancement. Specific Aim 2 develops an "action plan" to positively influence the translation and future directions of the bone tissue engineering field. In Aim 2A the workshop will occur as at the initiation of the TERMIS-NA meeting in Orlando FL on December 5, 2010 to capitalize on the assembly of world experts in attendance. In Aim 2B the workshop will be designed to attract students and trainees to the event. In Aim 2C a publication strategy is designed so that the meeting content and summary of the recommendations can be widely disseminated.. In summary, the development of integrative, realistic and effective strategies for regenerating human bone is a critical and unsolved problem. The workshop will the body of knowledge currently present in the various fields related to bone regeneration and will identify key areas for clinical translation towards improved bone regeneration strategies.

描述(申请人提供)：拟于2010年12月5日星期日在佛罗里达州奥兰多市举办为期一天的研讨会，题为“骨组织工程与再生：从发现到临床”。研讨会的目标是：i)确定该领域的最新水平；ii)确定哪些领域需要科学进步，以改进骨缺陷和受损愈合的翻译治疗；iii)制定一项将影响未来方向并使骨组织工程领域取得进展的“行动计划”。具体目标1旨在为临床医生、科学家、工程师、行业和政府代表提供一个论坛，讨论和定义推进骨组织工程的进展、机会和翻译需求。研讨会有一批优秀的科学参与者，杰出的女性和少数族裔科学家代表，并包括学生和受训人员。本次会议的主讲人将讨论指定研究领域内骨组织工程学的进展状况。重点将放在该领域的挑战和机遇以及与其他学科的协作和交叉对进步至关重要的领域。《特定目标2》制定了一项《行动计划》，对骨组织工程领域的翻译和未来发展方向产生积极影响。在Aim 2a中，讲习班将于2010年12月5日在佛罗里达州奥兰多举行的TERMIS-NA会议开始时举行，以利用出席的世界专家大会。在Aim 2B，讲习班的设计目的是吸引学生和受训人员参加这一活动。在目标2C中，制定了一项出版战略，以便能够广泛传播会议内容和建议摘要。综上所述，开发综合的、现实的和有效的人骨再生策略是一个关键的和尚未解决的问题。研讨会将介绍目前与骨再生相关的各个领域的知识体系，并将确定临床转化为改进骨再生策略的关键领域。