A Brief Family Intervention to Promote Adaptation to the Stress of Parental BMT

描述(申请人提供)：骨髓移植/造血干细胞移植(BMT)在治疗癌症方面的应用在世界范围内正在增加。这是一个高风险和挑战性的程序，扰乱了家庭和接受者的生活。研究表明，家庭照顾者，通常是伴侣/配偶，在二元关系中经历了比接受者所特有的更高程度的痛苦和更大的不满。在文献中，很少有关于这些接受者的孩子的经验性数据，然而，该研究团队最近完成的一篇论文表明，他们也受到了BMT导致的家庭内部的干扰和压力的影响。这项发展可行性研究将审查以家庭为重点的简短干预措施的有效性，以最大限度地减少骨髓移植对个别家庭成员的负面影响和家庭系统内的相互作用。它将包括父母二人组的三个说教/讨论环节和一张两部分的家庭DVD，供父母和孩子一起观看。拟议研究的设计将纳入从探索性研究中获得的数据，作为常规护理组。 公共卫生相关性：这项研究将开发和评估以家庭为重点的简短干预措施的有效性，以促进BMT接受者和家庭成员对这一具有挑战性的高风险程序的压力的积极适应。它的重点是预防由于骨髓移植导致的严重继发性心理和社会疾病，并将作为常规护理的一部分设计用于分娩。

DESCRIPTION (provided by applicant): The use of bone marrow transplantation/hematopoetic stem cell transplantation (BMT) for the treatment of cancer is increasing world-wide. It is a high risk and challenging procedure that disrupts the life of the family as well as that of the recipient. Research indicates that family caregivers, most often partners/spouses, experience higher levels of distress and greater dissatisfaction within the dyadic relationship than is characteristic of recipients. In the literature, there is little empirical data relative to the children of these recipients, however, a recently completed dissertation from this research team indicates they too are affected by the disturbance and stress that occurs within the family as a consequence of BMT. This developmental feasibility study will examine the effectiveness of a brief family-focused intervention in minimizing the negative impact of BMT on individual family members and interaction within the family system. It will include three didactic/discussion sessions for the parent dyad and a two part family DVD to be viewed by parents and children together. The design of the proposed study will incorporate data available from an exploratory study as the usual care group. PUBLIC HEALTH RELEVANCE: This study will develop and evaluate the effectiveness of a brief family-focused intervention to facilitate positive adaptation of the BMT recipient and family members to the stress of this challenging high-risk procedure. It is focused on the prevention of serious secondary psychological and social morbidity from occurring as a consequence of BMT, and it will be designed for delivery as a part of usual care.