A Brief Family Intervention to Promote Adaptation to the Stress of Parental BMT

描述（由申请人提供）：骨髓移植/造血干细胞移植（BMT）用于治疗癌症的使用在世界范围内不断增加。这是一个高风险和具有挑战性的程序，扰乱了家庭生活以及接受者的生活。研究表明，家庭照顾者，通常是伴侣/配偶，在这种二元关系中经历的痛苦和不满程度比接受者的特征更高。在文献中，很少有经验数据相对于这些收件人的孩子，但是，最近完成的论文从这个研究小组表明，他们也受到干扰和压力，发生在家庭内的BMT的结果。这项发展可行性研究将审查一个简短的家庭为重点的干预措施，在尽量减少BMT对个别家庭成员和家庭系统内的互动的负面影响的有效性。它将包括三个教学/讨论会议的父母二人组和两部分的家庭DVD，供父母和孩子一起观看。拟定研究的设计将纳入从探索性研究中获得的数据，作为常规治疗组。 公共卫生相关性：这项研究将开发和评估一个简短的家庭为重点的干预措施，以促进积极适应的BMT受体和家庭成员的压力，这一具有挑战性的高风险程序的有效性。它的重点是预防由于骨髓移植而发生严重的继发性心理和社会疾病，它将作为常规护理的一部分提供。

DESCRIPTION (provided by applicant): The use of bone marrow transplantation/hematopoetic stem cell transplantation (BMT) for the treatment of cancer is increasing world-wide. It is a high risk and challenging procedure that disrupts the life of the family as well as that of the recipient. Research indicates that family caregivers, most often partners/spouses, experience higher levels of distress and greater dissatisfaction within the dyadic relationship than is characteristic of recipients. In the literature, there is little empirical data relative to the children of these recipients, however, a recently completed dissertation from this research team indicates they too are affected by the disturbance and stress that occurs within the family as a consequence of BMT. This developmental feasibility study will examine the effectiveness of a brief family-focused intervention in minimizing the negative impact of BMT on individual family members and interaction within the family system. It will include three didactic/discussion sessions for the parent dyad and a two part family DVD to be viewed by parents and children together. The design of the proposed study will incorporate data available from an exploratory study as the usual care group. PUBLIC HEALTH RELEVANCE: This study will develop and evaluate the effectiveness of a brief family-focused intervention to facilitate positive adaptation of the BMT recipient and family members to the stress of this challenging high-risk procedure. It is focused on the prevention of serious secondary psychological and social morbidity from occurring as a consequence of BMT, and it will be designed for delivery as a part of usual care.