Organisation of the genome during the development of antibody-secreting cells

抗体分泌细胞发育过程中基因组的组织

• 批准号: nhmrc : 2001131
• 金额: $ 88.62万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/organisation-genome-development-secreting-cells/1779717
• 关键词: Organisation; genome; during; development; antibody

Each cell of our body contains over two metres of DNA that must be correctly packaged in order for our cells to function. We are using cutting-edge molecular biology techniques to study how this DNA circuitry is established in the white blood cells of our immune system that produce antibodies. Our novel approaches will reveal unique strategies to modulate immune responses to our benefit.

我们身体的每个细胞都含有超过两米的DNA，这些DNA必须正确包装才能使我们的细胞发挥功能。我们正在使用尖端的分子生物学技术来研究这种DNA回路是如何在我们免疫系统的白色血细胞中建立的，这些血细胞产生抗体。我们的新方法将揭示独特的策略来调节免疫反应，以使我们受益。