脂质过氧化诱导的胰岛素信号蛋白化学修饰-猫眼课题宝

脂质过氧化诱导的胰岛素信号蛋白化学修饰

批准号：

8119876

负责人：

Krisztian Stadler

金额：

$24.9万

依托单位：

LSU PENNINGTON BIOMEDICAL RESEARCH CTR

依托单位国家：

美国

项目类别：

财政年份：

2010

资助国家：

美国

项目状态：

已结题

起止时间：

2010-09-15 至 2013-08-31

来源：

https://reporter.nih.gov/project-details/8119876

关键词：

4 hydroxynonenal Acute Aftercare Aldehyde Reductase Aldehydes Animal Model Animals Atherosclerosis Attenuated Cardiovascular system Cause of Death Cells Chemicals Chronic Complications of Diabetes Mellitus Data Detection Development Diabetes Mellitus Diabetic Nephropathy Diet Disease Electron Spin Resonance Spectroscopy Enzymes Fatty acid glycerol esters Free Radical Formation Free Radicals Glucose Health Heart failure Human Hydroxyl Radical Hyperglycemia Image Impairment In Situ Incidence Inflammation Inflammatory Injection of therapeutic agent Insulin Insulin Receptor Insulin Resistance Insulin Signaling Pathway Insulin-Dependent Diabetes Mellitus Kidney Laboratories Lead Lipid Peroxidation Lipid Peroxides Lipids Liver Mediating Metabolic Diseases Methodology Methods Mitochondria Modeling Modification Mus NADP Neuropathy Nitrogen Non-Insulin-Dependent Diabetes Mellitus Obesity Oxidants Oxidative Stress Oxygen Participant Pathogenesis Pathway interactions Patients Pattern Peroxonitrite Phosphorylation Prevention Process Production Proteins Rattus Receptor Signaling Retinal Diseases Rodent Role Scheme Signal Pathway Signal Transduction Signaling Protein Site Skeletal Muscle Source Spin Trapping Staging Streptozocin Stress Techniques Testing Therapeutic Agents Time Tissues Work World Health Organization Xanthines Zucker Rats base clinically relevant diabetic diabetic patient diabetic rat glycation human NOS2A protein improved in vivo inhibitor/antagonist insight insulin receptor substrate 1 protein insulin sensitivity insulin signaling insulin tolerance macrophage nitration novel oral glucose tolerance overexpression oxidation polyol public health relevance research study restoration rosiglitazone type I and type II diabetes type I diabetic

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会议论文

Novel redox mechanisms of oxygenated phospholipids in chronic and diabetic kidney disease

批准号：

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项目类别：
资助金额：

$29.98万
财政年份：

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负责人：

Krisztian Stadler
依托单位：

LSU PENNINGTON BIOMEDICAL RESEARCH CTR

Mitochondrial overload and proximal tubular cell atrophy

批准号：

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项目类别：
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Lipid peroxidation-induced chemical modifications of insulin signaling proteins

批准号：

8327262
项目类别：
资助金额：

$24.65万
财政年份：

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负责人：

Krisztian Stadler
依托单位：

LSU PENNINGTON BIOMEDICAL RESEARCH CTR

Lipid peroxidation-induced chemical modifications of insulin signaling proteins

批准号：

8142216
项目类别：
资助金额：

$24.65万
财政年份：

2010
负责人：

Krisztian Stadler
依托单位：

LSU PENNINGTON BIOMEDICAL RESEARCH CTR

海外基金