16th international conference on Campylobacter, Helicobacter and related organism

简介(申请人提供)：我们拟于2011年8月28日至9月1日在温哥华举办第16届国际弯曲杆菌、幽门螺杆菌及相关生物研讨会。在过去的25年里，我们在世界各地与该领域的世界领先权威举行了会议。这个两年一度的研讨会始于1981年，是一个国际论坛，致力于增进我们对这组迷人的细菌病原体的了解。空肠弯曲杆菌现在已经成为发达国家和发展中国家细菌性腹泻的主要原因。空肠弯曲菌也是格林-巴利综合征的主要原因之一，并继续吸引着全世界的密集研究。弯曲杆菌的基因组/蛋白质组/糖组学研究在了解疾病发病机制、生物学和生物体方面取得了重要进展。1983年在布鲁塞尔举行的第二次研讨会上，幽门螺杆菌(当时名为幽门弯曲菌)被引入世界，开启了胃十二指肠疾病的微生物学革命。幽门螺杆菌与胃炎、消化性溃疡和胃癌的关系现已得到普遍认可。随着许多科学家和临床医生为此而努力，对涉及幽门螺杆菌的疾病过程以及预防或控制手段的了解似乎是触手可及的。为了表彰幽门螺杆菌的重要性，巴里·马歇尔和罗宾·沃伦因他们的发现在2005年获得了诺贝尔医学奖，巴里·马歇尔仍然非常积极地参加CHRO会议，并在2009年在日本新泻举行的CHRO会议上发表了主旨演讲。CHRO会议一直是，并将继续是介绍弯曲杆菌和螺杆菌研究成果的主要场所。这次会议的目标是1)聚集来自世界各地的初级和高级研究人员，他们专门研究弯曲杆菌、螺杆菌和相关生物引起的疾病的方方面面。这些领域包括微生物发病机制、基因组学/蛋白质组学/糖组学、感染免疫学、胃肠道病理生理学、临床管理、公共卫生、食品安全和人与动物生态学；2)由在各自领域内的专家和发病机制方面的领军人物的主旨演讲者介绍这些不同领域的概述和最新进展；3)在海报会议和简短的应邀演讲中展示研究人员在这些不同领域的最新结果；4)促进新的协作多学科互动，以解决弯曲杆菌和幽门螺杆菌引起的疾病的发病机制、预防和治疗等紧迫问题，以及5)培养和鼓励来自世界不同地区的年轻科学家积极参与弯曲杆菌和螺杆菌的研究。资金将作为旅行津贴提供给学生和初级研究人员，以实现这一目标。CHRO会议涉及NIAID以及NIDDK和NCI感兴趣的许多领域。CHRO会议的重点是了解弯曲杆菌和幽门螺杆菌感染的自然历史、发病机制以及宿主和免疫反应。CHRO是展示为这些感染开发疫苗的新工作的主要场所。最后，对这些胃肠道病原体的基因组学/蛋白质组/糖学分析是CHRO会议上提出的一个新的重要研究领域，有助于我们理解感染的发病机制。 公共卫生相关性：项目叙述弯曲杆菌和螺杆菌是全世界数百万感染的原因，在资源丰富和资源挑战的国家都造成了显著的发病率。第16届弯曲杆菌、幽门螺杆菌和相关生物研讨会(CHRO2011)将为学生、初级和有经验的研究人员提供一个论坛，介绍新的研究并讨论旨在减轻这些感染对人类的负担的方法。

DESCRIPTION (provided by applicant): We propose to host the 16th International Workshop on Campylobacter, Helicobacter and Related Organisms (CHRO) from August 28 - September 1, 2011 in Vancouver. Over the past 25 years, our meetings have been held around the world with the world's leading authorities in the field. This biennial workshop, started in 1981, is an international forum dedicated to enhancing our knowledge of this fascinating group of bacterial pathogens. Campylobacter jejuni is now firmly established as a major cause of bacterial diarrhea in both developed and developing countries. C. jejuni is also one of the major causes of the Guillain-Barre syndrome and continues attracting intense investigation worldwide. Genomic/proteomic/glycomic research on Campylobacter has made important strides on understanding disease pathogenesis and biology and the organism. At the 2nd workshop in Brussels in 1983, Helicobacter pylori (then named Campylobacter pylori) was introduced to the world and the microbiological revolution of gastroduodenal disease began. The association of H. pylori with gastritis, peptic ulcers and gastric carcinoma is now universally recognized. An understanding of the disease process involving H. pylori and hopefully, the means to prevent or control appears to be within reach as a great many scientists and clinicians are striving towards this end. In recognition of the importance of H. pylori, Barry Marshall and Robin Warren were awarded the Nobel Prize in Medicine in 2005 for their discoveries and Barry Marshall remains very active with CHRO meetings and gave a keynote address at the past CHRO meeting in Niigata, Japan in 2009. CHRO meetings have, and continue to be, the major venue for presenting research findings on Campylobacter and Helicobacter. The goals of this conference are 1) to gather junior and senior investigators from around the world who specialize in areas encompassing all aspects of disease due to Campylobacter, Helicobacter and related organisms. These areas include microbial pathogenesis, genomics/proteomics/glycomics, immunology of infections, gastrointestinal pathophysiology, clinical management, public health, food safety, and human and animal ecology; 2) present overviews and updates in these diverse areas by keynote speakers who are experts in their field both inside the field and leading figures in pathogenesis; 3) present the latest results form investigators in these diverse areas in poster sessions and short invited talks; 4) foster new collaborative multi-disciplinary interactions to address pressing questions of pathogenesis, prevention and treatment of diseases due to Campylobacter and Helicobacter and 5) foster and encourage young scientists from different areas of the world to become actively involved in research on Campylobacter and Helicobacter. Funds will be provided as travel grants to students and junior researchers to accomplish this. CHRO meetings address many areas of interest to NIAID as well as NIDDK and NCI. The CHRO meetings focus on understanding the natural history, pathogenesis, and host and immunological responses to infection by Campylobacter and Helicobacter. CHRO is a major venue for presenting new work on developing vaccines for these infections. Finally, genomics/proteomic/glycomic analysis of these gastrointestinal pathogens are a new and important area of research presented at CHRO meetings that contribute to our understanding of the pathogenesis of infections. PUBLIC HEALTH RELEVANCE: Project Narrative Campylobacter and Helicobacter are the cause of millions of infections worldwide and cause significant morbidity in both resource -rich and resource-challenged nations. The 16th Workshop of Campylobacter, Helicobacter and Related Organisms (CHRO2011) will provide a forum for students, junior and experienced researchers to present new research and discuss approaches that are aimed in reducing the burden of these infections in humans.