2011 Rachmiel Levine Diabetes and Obesity Symposium: Advances in Diabetes Biology

描述（申请人提供）：2011年Rachmiel Levine糖尿病和肥胖研讨会R13资助申请每年，希望之城的糖尿病、内分泌和代谢部门都会举办一次年度糖尿病研讨会，以荣誉已故的Rachmiel Levine博士，他是负责鉴定人类胰岛素的科学家--这一重要发现已经帮助挽救了世界各地数百万患者的生命，至今仍被用于治疗。因此，莱文研讨会的使命是汇集国际领先的科学家，以及年轻的研究人员和学生，汇集新的想法和知识，这将直接导致我们的能力的重大进步，以对抗，预防，甚至治愈糖尿病。在过去的几年里，莱文研讨会计划全面涵盖了1型和2型糖尿病研究中最新和最重要的主题，每年有来自22个国家和30个美国州的近400名科学家，医生，研究员和学生参加。2011年Rachmiel Levine研讨会题为“糖尿病生物学、免疫学和细胞治疗的进展”，将于2011年3月20日至23日在加州帕萨迪纳的朗廷亨廷顿酒店举行，将重点讨论胰岛免疫学和炎症、β细胞再生和存活、糖尿病和癌症之间的联系以及糖尿病新技术，包括人工胰腺、体内胰岛成像和生物相容性装置在胰岛移植中的应用。所有的演讲都将联系1型和2型糖尿病的研究，并提供对该领域最新发展的见解。会议还将讨论更具争议性的话题，如人源化小鼠，病毒感染在1型糖尿病中的作用，以及调节性T细胞（及其在1型糖尿病中的潜在缺陷）。该计划还将包括最近的临床试验结果，胰岛生物学技术研讨会，以及年轻研究人员的口头报告，以便与该领域更有经验的人进行更多的互动。一个海报会议和一个主题演讲晚宴将完成该计划。今年的会议预计将吸引来自美国和国外，因为它在过去，著名的科学家，内分泌学家，糖尿病学家，胰岛生物学家，干细胞和基因转移科学家，移植科学家，免疫学家，细胞生物学家，以及在所有上述领域的年轻研究人员，除了参与糖尿病患者管理的其他卫生保健专业人员外。 公共卫生相关性：2011年Rachmiel Levine糖尿病和肥胖研讨会R13资助申请第11届年度Rachmiel Levine糖尿病和肥胖研讨会将继续为研究人员提供一个最先进的，全面的国际口径和范围的科学论坛，涵盖胰岛免疫学和炎症，β细胞再生和存活，糖尿病和癌症之间的联系，以及糖尿病的新技术，包括人工胰腺、体内胰岛成像和生物相容性装置在胰岛移植中的应用。会议还将讨论最新的争议性话题，包括人源化小鼠，病毒感染在1型糖尿病中的作用，以及调节性T细胞（及其在1型糖尿病中的潜在缺陷）。此外，还将举办关于胰岛制备和质量检测方法的讲习班。过去，研讨会为参与糖尿病和肥胖症研究和护理的科学和医学界提供了宝贵的知识共享来源，并将继续促进年轻科学家和未来领导者之间的新互动和合作。

DESCRIPTION (provided by applicant): 2011 Rachmiel Levine Diabetes and Obesity Symposium R13 Grant Application Each year, the Department of Diabetes, Endocrinology and Metabolism at City of Hope holds an annual diabetes symposium named in honor of the late Dr. Rachmiel Levine, the scientist responsible for identifying human insulin-a vital discovery that has already helped save the lives of millions of patients around the world, and continues to be used in treatment today. Thus, the Levine Symposium is charged with the mission of bringing together leading international scientists, as well as young investigators and students, for the purpose of pooling new ideas and knowledge that will directly lead to major advances in our ability to fight, prevent, and even cure diabetes. In prior years, the Levine Symposium program has comprehensively covered the latest and most important topics in type 1 and type 2 diabetes research, with the highest annual attendance of nearly 400 scientists, physicians, fellows, and students from 22 countries and 30 U.S. states. The 2011 Rachmiel Levine Symposium, entitled "Advances in Diabetes Biology, Immunology, and Cell Therapy" will be held March 20-23, 2011 at The Langham Huntington Hotel in Pasadena, California, and will highlight topics in islet immunology and inflammation, beta cell regeneration and survival, the link between diabetes and cancer, and new technologies in diabetes, including the artificial pancreas, in vivo islet imaging, and use of biocompatibility devices in islet transplantation. All presentations will link type 1 and type 2 diabetes research, and provide insight into the most recent developments in the field. The meeting will also feature debates on more controversial topics, such as the humanized mouse, the role of virus infection in type 1 diabetes, and regulatory T-cells (and their underlying defects in type 1 diabetes). The program will also include the results of recent clinical trials, technical workshops in islet biology, and oral presentations from young investigators to allow for greater interaction with those more experienced in the field. A poster session and a keynote dinner lectureship will complete the program. This year's meeting is expected to attract from both the U.S. and abroad, as it has in the past, well-established scientists, endocrinologists, diabetologists, islet biologists, stem cell and gene transfer scientists, transplant scientists, immunologists, cell biologists, as well as young investigators in all of the previously mentioned fields, in addition to other health care professionals involved in the management of patients with diabetes.. PUBLIC HEALTH RELEVANCE: 2011 Rachmiel Levine Diabetes and Obesity Symposium R13 Grant Application The 11th Annual Rachmiel Levine Diabetes and Obesity Symposium will continue to offer investigators a state- of-the-art, comprehensive scientific forum of international caliber and scope by covering topics in islet immunology and inflammation, beta cell regeneration and survival, the links between diabetes and cancer, and new technologies in diabetes, including the artificial pancreas, in vivo islet imaging, and use of biocompatibility devices in islet transplantation. The meeting will also present debates on the latest controversial topics, including the humanized mouse, the role of virus infection in type 1 diabetes, and regulatory T-cells (and their underlying defect(s) in type 1 diabetes). Additionally, workshops will be offered on methods of islet preparation and quality testing. In the past, the Symposium has represented an invaluable source of knowledge sharing for the scientific and medical communities involved in diabetes and obesity research and care, and it will continue to promote new interactions and collaborations among young scientists and established leaders in the future.