2011 Rachmiel Levine Diabetes and Obesity Symposium: Advances in Diabetes Biology

2011 年 Rachmiel Levine 糖尿病与肥胖研讨会：糖尿病生物学进展

• 批准号: 8131443
• 负责人: FOUAD R KANDEEL
• 金额: $ 0.8万
• 依托单位: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8131443
• 关键词: Applications Grants; Artificial Pancreas; Beta Cell; Biology; Caliber; California; Caring; Cell Therapy; Cells; Charge; Cities; Clinical Trials; Collaborations; Communities; Country; Defect; Development; Devices; Diabetes Mellitus; Educational Activities; Educational workshop; Endocrinologist; Endocrinology; Fostering; Funding Agency; Funding Opportunities; Future; Gene Transfer; Geographic state; Goals; Growth; Health Professional; Human; Huntington Disease; Image; Immunologist; Immunology; Inflammation; Insulin; Insulin-Dependent Diabetes Mellitus; International; Islets of Langerhans Transplantation; Knowledge; Laboratory Study; Lead; Link; Malignant Neoplasms; Medical; Methodology; Methods; Mission; Mus; Names; Natural regeneration; Obesity; Participant; Patient Care; Patients; Physicians; Preparation; Regulatory T-Lymphocyte; Research; Research Activity; Research Personnel; Research Support; Role; Scientist; Source; Stem cells; Students; Testing; Transplantation; Virus Diseases; biomaterial compatibility; career; experience; fighting; in vivo; insight; islet; meetings; new technology; oral biology; posters; prevent; programs; symposium; type I and type II diabetes

DESCRIPTION (provided by applicant): 2011 Rachmiel Levine Diabetes and Obesity Symposium R13 Grant Application Each year, the Department of Diabetes, Endocrinology and Metabolism at City of Hope holds an annual diabetes symposium named in honor of the late Dr. Rachmiel Levine, the scientist responsible for identifying human insulin-a vital discovery that has already helped save the lives of millions of patients around the world, and continues to be used in treatment today. Thus, the Levine Symposium is charged with the mission of bringing together leading international scientists, as well as young investigators and students, for the purpose of pooling new ideas and knowledge that will directly lead to major advances in our ability to fight, prevent, and even cure diabetes. In prior years, the Levine Symposium program has comprehensively covered the latest and most important topics in type 1 and type 2 diabetes research, with the highest annual attendance of nearly 400 scientists, physicians, fellows, and students from 22 countries and 30 U.S. states. The 2011 Rachmiel Levine Symposium, entitled "Advances in Diabetes Biology, Immunology, and Cell Therapy" will be held March 20-23, 2011 at The Langham Huntington Hotel in Pasadena, California, and will highlight topics in islet immunology and inflammation, beta cell regeneration and survival, the link between diabetes and cancer, and new technologies in diabetes, including the artificial pancreas, in vivo islet imaging, and use of biocompatibility devices in islet transplantation. All presentations will link type 1 and type 2 diabetes research, and provide insight into the most recent developments in the field. The meeting will also feature debates on more controversial topics, such as the humanized mouse, the role of virus infection in type 1 diabetes, and regulatory T-cells (and their underlying defects in type 1 diabetes). The program will also include the results of recent clinical trials, technical workshops in islet biology, and oral presentations from young investigators to allow for greater interaction with those more experienced in the field. A poster session and a keynote dinner lectureship will complete the program. This year's meeting is expected to attract from both the U.S. and abroad, as it has in the past, well-established scientists, endocrinologists, diabetologists, islet biologists, stem cell and gene transfer scientists, transplant scientists, immunologists, cell biologists, as well as young investigators in all of the previously mentioned fields, in addition to other health care professionals involved in the management of patients with diabetes.. PUBLIC HEALTH RELEVANCE: 2011 Rachmiel Levine Diabetes and Obesity Symposium R13 Grant Application The 11th Annual Rachmiel Levine Diabetes and Obesity Symposium will continue to offer investigators a state- of-the-art, comprehensive scientific forum of international caliber and scope by covering topics in islet immunology and inflammation, beta cell regeneration and survival, the links between diabetes and cancer, and new technologies in diabetes, including the artificial pancreas, in vivo islet imaging, and use of biocompatibility devices in islet transplantation. The meeting will also present debates on the latest controversial topics, including the humanized mouse, the role of virus infection in type 1 diabetes, and regulatory T-cells (and their underlying defect(s) in type 1 diabetes). Additionally, workshops will be offered on methods of islet preparation and quality testing. In the past, the Symposium has represented an invaluable source of knowledge sharing for the scientific and medical communities involved in diabetes and obesity research and care, and it will continue to promote new interactions and collaborations among young scientists and established leaders in the future.

描述（由申请人提供）： 2011 年 Rachmiel Levine 糖尿病和肥胖研讨会 R13 拨款申请 每年，希望之城的糖尿病、内分泌和代谢科都会举办年度糖尿病研讨会，以纪念已故的 Rachmiel Levine 博士，他是负责识别人胰岛素的科学家，这一重要发现已经帮助拯救了世界各地数百万患者的生命，并且 至今仍继续用于治疗。因此，莱文研讨会的使命是将国际领先的科学家以及年轻的研究人员和学生聚集在一起，目的是汇集新的想法和知识，从而直接导致我们对抗、预防甚至治愈糖尿病的能力取得重大进步。前几年，莱文研讨会项目全面涵盖了 1 型和 2 型糖尿病研究的最新和最重要的主题，每年有来自 22 个国家和美国 30 个州的近 400 名科学家、医生、研究员和学生参加。题为“糖尿病生物学、免疫学和细胞治疗进展”的 2011 年 Rachmiel Levine 研讨会将于 2011 年 3 月 20 日至 23 日在加利福尼亚州帕萨迪纳的朗廷亨廷顿酒店举行，重点讨论胰岛免疫学和炎症、β 细胞再生和存活、糖尿病和癌症之间的联系以及糖尿病新技术（包括人工糖尿病）等主题。 胰腺、体内胰岛成像以及生物相容性设备在胰岛移植中的使用。所有演讲都将把 1 型和 2 型糖尿病研究联系起来，并深入了解该领域的最新发展。会议还将就更具争议性的话题进行辩论，例如人源化小鼠、病毒感染在 1 型糖尿病中的作用以及调节性 T 细胞（及其在 1 型糖尿病中的潜在缺陷）。该计划还将包括最近的临床试验结果、胰岛生物学技术研讨会以及年轻研究人员的口头报告，以便与该领域更有经验的人员进行更多互动。海报会议和主题晚宴演讲将完成该计划。与往届一样，今年的会议预计将吸引来自美国和国外的知名科学家、内分泌学家、糖尿病学家、胰岛生物学家、干细胞和基因转移科学家、移植科学家、免疫学家、细胞生物学家以及上述所有领域的年轻研究人员，以及参与糖尿病患者管理的其他医疗保健专业人员。 公共健康相关性：2011 年 Rachmiel Levine 糖尿病和肥胖研讨会 R13 拨款申请 第 11 届年度 Rachmiel Levine 糖尿病和肥胖研讨会将继续为研究人员提供一个最先进、具有国际水准和范围的综合性科学论坛，涵盖胰岛免疫学和炎症、β 细胞再生和存活、糖尿病和癌症之间的联系以及新的研究主题。 糖尿病领域的技术，包括人工胰腺、体内胰岛成像以及生物相容性设备在胰岛移植中的使用。会议还将就最新有争议的话题进行辩论，包括人源化小鼠、病毒感染在 1 型糖尿病中的作用以及调节性 T 细胞（及其在 1 型糖尿病中的潜在缺陷）。此外，还将举办有关胰岛制备和质量测试方法的研讨会。过去，研讨会为参与糖尿病和肥胖症研究和护理的科学界和医学界提供了宝贵的知识共享来源，未来将继续促进年轻科学家和知名领导者之间的新互动和合作。