2011 Rachmiel Levine Diabetes and Obesity Symposium: Advances in Diabetes Biology

描述(申请人提供)：2011 Rachmiel Levine糖尿病和肥胖研讨会R13拨款申请每年，希望之城的糖尿病、内分泌学和新陈代谢系都会举办一年一度的糖尿病研讨会，以纪念已故的Rachmiel Levine博士，他是一位负责识别人类胰岛素的科学家-这一重大发现已经帮助挽救了世界各地数百万患者的生命，今天仍在用于治疗。因此，莱文研讨会肩负着将国际领先的科学家以及年轻的研究人员和学生聚集在一起的使命，目的是汇集新的想法和知识，这些新想法和知识将直接导致我们抗击、预防甚至治愈糖尿病的能力取得重大进展。前几年，莱文研讨会项目全面涵盖了1型和2型糖尿病研究的最新和最重要的主题，每年出席人数最多的是来自22个国家和美国30个州的近400名科学家、医生、研究员和学生。2011年Rachmiel Levine研讨会题为“糖尿病生物学、免疫学和细胞治疗的进展”，将于2011年3月20-23日在加利福尼亚州帕萨迪纳市朗廷亨廷顿酒店举行，会议将重点讨论胰岛免疫学和炎症、β细胞再生和生存、糖尿病和癌症之间的联系，以及糖尿病新技术，包括人工胰腺、活体胰岛成像以及胰岛移植中生物相容性设备的使用等主题。所有的报告都将链接1型和2型糖尿病的研究，并提供对该领域最新发展的洞察。会议还将就更具争议性的话题进行辩论，如人源化小鼠、病毒感染在1型糖尿病中的作用，以及调节性T细胞(及其在1型糖尿病中的潜在缺陷)。该计划还将包括最近的临床试验结果，胰岛生物学的技术研讨会，以及年轻研究人员的口头陈述，以允许与该领域更有经验的人进行更多互动。海报环节和主旨晚宴演讲将完成节目。与过去一样，今年的会议预计将吸引来自美国和海外的知名科学家、内分泌学家、糖尿病专家、胰岛生物学家、干细胞和基因转移科学家、移植科学家、免疫学家、细胞生物学家以及上述所有领域的年轻研究人员，以及参与糖尿病患者管理的其他卫生保健专业人员。 与公众健康相关：2011年Rachmiel Levine糖尿病与肥胖研讨会R13批准申请第11届Rachmiel Levine糖尿病与肥胖研讨会将继续为研究人员提供一个具有国际水准和范围的先进的、综合性的科学论坛，主题包括胰岛免疫学与炎症、β细胞再生与生存、糖尿病与癌症之间的联系，以及糖尿病方面的新技术，包括人工胰腺、活体胰岛成像，以及在胰岛移植中使用生物相容性设备。会议还将就最新的争议话题进行辩论，包括人源化小鼠、病毒感染在1型糖尿病中的作用，以及调节性T细胞(以及它们在1型糖尿病中的潜在缺陷(S))。此外，还将举办关于胰岛制备方法和质量检测的讲习班。过去，研讨会为参与糖尿病和肥胖症研究和护理的科学界和医学界提供了宝贵的知识共享来源，并将在未来继续促进青年科学家和知名领导人之间的新的互动和合作。

DESCRIPTION (provided by applicant): 2011 Rachmiel Levine Diabetes and Obesity Symposium R13 Grant Application Each year, the Department of Diabetes, Endocrinology and Metabolism at City of Hope holds an annual diabetes symposium named in honor of the late Dr. Rachmiel Levine, the scientist responsible for identifying human insulin-a vital discovery that has already helped save the lives of millions of patients around the world, and continues to be used in treatment today. Thus, the Levine Symposium is charged with the mission of bringing together leading international scientists, as well as young investigators and students, for the purpose of pooling new ideas and knowledge that will directly lead to major advances in our ability to fight, prevent, and even cure diabetes. In prior years, the Levine Symposium program has comprehensively covered the latest and most important topics in type 1 and type 2 diabetes research, with the highest annual attendance of nearly 400 scientists, physicians, fellows, and students from 22 countries and 30 U.S. states. The 2011 Rachmiel Levine Symposium, entitled "Advances in Diabetes Biology, Immunology, and Cell Therapy" will be held March 20-23, 2011 at The Langham Huntington Hotel in Pasadena, California, and will highlight topics in islet immunology and inflammation, beta cell regeneration and survival, the link between diabetes and cancer, and new technologies in diabetes, including the artificial pancreas, in vivo islet imaging, and use of biocompatibility devices in islet transplantation. All presentations will link type 1 and type 2 diabetes research, and provide insight into the most recent developments in the field. The meeting will also feature debates on more controversial topics, such as the humanized mouse, the role of virus infection in type 1 diabetes, and regulatory T-cells (and their underlying defects in type 1 diabetes). The program will also include the results of recent clinical trials, technical workshops in islet biology, and oral presentations from young investigators to allow for greater interaction with those more experienced in the field. A poster session and a keynote dinner lectureship will complete the program. This year's meeting is expected to attract from both the U.S. and abroad, as it has in the past, well-established scientists, endocrinologists, diabetologists, islet biologists, stem cell and gene transfer scientists, transplant scientists, immunologists, cell biologists, as well as young investigators in all of the previously mentioned fields, in addition to other health care professionals involved in the management of patients with diabetes.. PUBLIC HEALTH RELEVANCE: 2011 Rachmiel Levine Diabetes and Obesity Symposium R13 Grant Application The 11th Annual Rachmiel Levine Diabetes and Obesity Symposium will continue to offer investigators a state- of-the-art, comprehensive scientific forum of international caliber and scope by covering topics in islet immunology and inflammation, beta cell regeneration and survival, the links between diabetes and cancer, and new technologies in diabetes, including the artificial pancreas, in vivo islet imaging, and use of biocompatibility devices in islet transplantation. The meeting will also present debates on the latest controversial topics, including the humanized mouse, the role of virus infection in type 1 diabetes, and regulatory T-cells (and their underlying defect(s) in type 1 diabetes). Additionally, workshops will be offered on methods of islet preparation and quality testing. In the past, the Symposium has represented an invaluable source of knowledge sharing for the scientific and medical communities involved in diabetes and obesity research and care, and it will continue to promote new interactions and collaborations among young scientists and established leaders in the future.