HPV Vaccination in the Cambodian Community

柬埔寨社区的 HPV 疫苗接种

• 批准号: 8133619
• 负责人: VICTORIA M TAYLOR
• 金额: $ 19.14万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-06 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8133619
• 关键词: Address; Adolescent; Age; American; Area; Asians; Attention; Birth; California; Characteristics; Child; Child health care; Collaborations; Communities; Data; Daughter; Development; Dose; Economically Deprived Population; Educational Intervention; Educational Materials; Ethnic group; Evaluation; Fathers; Female Adolescents; Goals; Health; Health Priorities; Health behavior; Human Papilloma Virus Vaccine; Human Papillomavirus; Human papilloma virus infection; Human papillomavirus 16; Immigrant; Immunization; Incidence; Individual; Intervention; Interview; Life; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Measures; Methods; Morbidity - disease rate; Mothers; NIH Program Announcements; Not Hispanic or Latino; Participant; Patient Self-Report; Phase; Population; Prevention; Preventive; Preventive Intervention; Procedures; Publications; Qualitative Methods; Recording of previous events; Relative (related person); Research; Research Methodology; Research Personnel; Research Project Grants; Research Support; Sampling; Series; Surveys; Teenagers; Telephone; Testing; Underserved Population; United States; Vaccination; Vaccines; Washington; Woman; age group; base; behavioral/social science; community based participatory research; disorder prevention; experience; girls; health disparity; intervention program; metropolitan; mortality; prevent; racial and ethnic; social science research; southeast Asian; uptake

DESCRIPTION (provided by applicant): Cervical cancer is a major cause of morbidity and mortality. Virtually all cancers of the cervix are caused by HPV infection. Several HPV vaccines (that could prevent 70 percent of all cervical cancers) have been approved for American girls and young women. The majority of Cambodian Americans came to the US as immigrants and over one-half have limited English proficiency. Women of Southeast Asian descent have higher cervical cancer incidence rates than any other racial/ethnic group, and the incidence among Cambodians is twice the incidence among non-Hispanic whites (15.0 versus 7.7 per 100,000). The study goal is to conduct mixed-methods research that could be used to inform the development, implementation, and evaluation of culturally appropriate HPV vaccination interventions targeting Cambodian women with daughters in the 9-17 age group. Qualitative and quantitative methods should both be used to examine determinants of preventive health practices in Southeast Asian and other immigrant groups. Our primary objectives are: to provide qualitative data relevant to the promotion of HPV vaccine use in Cambodian communities; and quantitative data about the uptake of HPV vaccination among Cambodian adolescents, as well as correlates of HPV vaccine uptake. A recent review of HPV vaccine surveillance in the US found no publications addressing the reliability of self-reported HPV vaccine uptake. Our secondary objective is to assess the test-retest reliability of survey measures addressing HPV vaccine uptake in a Cambodian study group. Our community-based participatory research will build on a long-standing collaboration with the Cambodian community. An existing Cambodian Community Coalition will serve as the community advisory board for the project. Cambodian women who have a daughter in the 9-17 age group and live in the Seattle-Tacoma metropolitan area will be included in this study. Our research will use the theoretical perspective of the Health Behavior Framework. Qualitative and quantitative study phases will be conducted sequentially. We will complete 25 qualitative interviews with Cambodian mothers. Qualitative data findings will be used to guide the development of a quantitative survey instrument. A community-based telephone survey of 200 Cambodian mothers will be conducted, and a sub-sample of 50 survey participants will be asked to complete a retest survey. PUBLIC HEALTH RELEVANCE: This project will provide valuable qualitative and quantitative information about HPV vaccination in the Cambodian community. Project findings could be used to guide the development, implementation, and evaluation of culturally appropriate HPV vaccination educational materials and intervention programs for Cambodian Americans.

描述（由申请人提供）：宫颈癌是发病率和死亡率的主要原因。几乎所有子宫颈的癌症都是由HPV感染引起的。已批准了几种HPV疫苗（可以预防所有宫颈癌的70％）已被批准用于美国女孩和年轻女性。大多数柬埔寨美国人以移民的身份来到美国，而超过一半的英语水平有限。东南亚血统的妇女的宫颈癌发病率比任何其他种族/族裔群体都高，柬埔寨人的发病率是非西班牙裔白人的发病率的两倍（15.0 vess 15.0对每100,000个）。研究的目标是进行混合方法研究，可用于告知针对柬埔寨女性在9-17岁年龄段的柬埔寨妇女的文化适当的HPV疫苗接种干预措施的发展，实施和评估。定性和定量方法均应用于检查东南亚和其他移民群体中预防健康实践的决定因素。我们的主要目标是：提供与柬埔寨社区中HPV疫苗使用有关的定性数据；以及有关柬埔寨青少年中HPV疫苗接种的摄取的定量数据，以及HPV疫苗摄取的相关性。最近对美国HPV疫苗监视的评论发现，没有出版物涉及自我报告的HPV疫苗摄取的可靠性。我们的次要目标是评估柬埔寨研究组中针对HPV疫苗摄取的调查措施的重测可靠性。我们基于社区的参与性研究将以与柬埔寨社区的长期合作为基础。现有的柬埔寨社区联盟将担任该项目的社区顾问委员会。这项研究将包括在9-17岁年龄段并居住在西雅图 - 塔科马都会区的柬埔寨妇女。我们的研究将使用健康行为框架的理论观点。定性和定量研究阶段将依次进行。我们将对柬埔寨母亲进行25次定性采访。定性数据发现将用于指导定量调查工具的开发。将对200名柬埔寨母亲进行基于社区的电话调查，并将要求50名调查参与者的子样本完成重新测试。 公共卫生相关性：该项目将在柬埔寨社区提供有关HPV疫苗接种的宝贵定性和定量信息。项目发现可用于指导对柬埔寨美国人的文化适当的HPV疫苗接种材料和干预计划的开发，实施和评估。