Sensory Mechanisms and Disorders

描述（由申请人提供）：该培训计划为博士前，博士后和本科学员提供听力，平衡和化学感官（HBCS）的跨学科教育和研究经验。博士前培训是基于15个学术部门和学位授予研究生课程之一，其中28个培训教师相关联。博士论文研究和博士后研究培训主要在导师的实验室内进行。我们的附属教师提供各自相应学科的优秀培训：生物工程，细胞和分子生物学，遗传学，分子和神经生理学，发育生物学和感觉处理的生物心理学。HBCS计划将听觉，前庭和化学感觉研究的研究人员与来自这些学科的受训人员相结合，从而为听力，平衡，味觉和嗅觉的机制和障碍提供创新的培训机会。跨学科的整合是通过培训计划，通过：a）介绍和高级课程的感觉系统; B）研讨会在听力，平衡和化学感官与来自密歇根大学内外的专家; c）学生和教师研讨会，期刊俱乐部和研究论坛; d）接触耳鼻喉科的临床研究问题和密歇根大学医学院的临床/翻译资源，以及d）研究标准和道德方面的培训。需要为5名博士前和4名博士后学员提供支助。博士预科生将从培训学院附属部门和项目中最高素质的研究生中挑选。对感觉系统研究的兴趣和动机将是一个重要的标准。博士后必须具有博士学位等博士学位。或者医学博士和对感官生物学的坚定承诺。还要求提供支助，以招募听力受损者参加生物医学研究。聋人在科学和医学专业中的代表性明显不足。我们的科学导师计划（SMP）的目标是为这些代表性不足的个人提供直接接触感官科学的主流研究，以便更好地为他们进入研究生和专业学校做好准备。我们建议继续SMP，开始于1990年，每年培训5名聋人本科生在夏季研究实习。 相关性：我们这个培训计划的主要目标是吸引有前途的科学家到听觉，平衡，味觉和嗅觉的研究领域，并为他们提供指导和培训，这将导致他们在这些领域追求富有成效的研究事业。更好地了解这些领域的感觉神经科学将提供重要的洞察许多人类感觉障碍，极大地影响生活质量。

DESCRIPTION (provided by applicant): This training program for predoctoral, postdoctoral, and undergraduate trainees provides an interdisciplinary education and research experience in hearing, balance and chemical senses (HBCS). Predoctoral training is based in one of the 15 academic departments and degree-granting graduate programs with which the 28 training faculty are associated. Doctoral thesis research and postdoctoral research training reside primarily within the laboratories of the mentors. Our affiliated faculty provides outstanding training in each of their corresponding disciplines: bioengineering, cellular and molecular biology, genetics, molecular and neurophysiology, developmental biology, and biopsychology of sensory processing. The HBCS program integrates investigators in auditory, vestibular and chemosensory research with trainees from across these disciplines and thereby fosters innovative training opportunities into mechanisms and disorders of hearing, balance, taste and smell. Cross-disciplinary integration is made possible by the training program through: a) introductory and advanced courses in sensory systems; b) seminars in hearing, balance and chemical senses with experts from within and outside the University of Michigan; c) student and faculty seminars, journal clubs and research forums; d) exposure to clinical research issues in Otolaryngology and clinical/translational resources available at the University of Michigan Medical School, and d) training in research standards and ethics. Support for 5 predoctoral and 4 postdoctoral trainees is requested. Predoctoral trainees will be selected from the most highly qualified graduate students in the training faculty's affiliated departments and programs. Interest and motivation for research in sensory systems will be an important criterion. Postdoctoral trainees must have a doctoral degree such as a Ph.D. or M.D. and a strong commitment to sensory biology. Support is also requested to recruit hearing impaired individuals into biomedical research. The deaf are clearly underrepresented in scientific and medical professions. The goal of our Science Mentorship Program (SMP) is to provide these under-represented individuals with direct exposure to mainstream research in the sensory sciences in order to better prepare them for entry into graduate and professional schools. We propose to continue the SMP, begun in 1990, by training 5 deaf undergraduate students per year in summer research internships. RELEVANCE: Our primary goal for this training program is to attract promising scientists to the research fields of hearing, balance, taste and smell and to provide them with the mentoring and training that will result in their pursuit of productive research careers in these areas. A better understanding of these areas of sensory neuroscience will provide important insight into many human sensory disorders that greatly affect quality of life.