LARGE-SCALE CLASSIFICATION AND QUANTITATIVE GENETIC STUDIES OF READING

阅读的大规模分类和定量遗传学研究

• 批准号: 7995980
• 负责人: RICHARD K WAGNER
• 金额: $ 16.49万
• 依托单位: FLORIDA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7995980
• 关键词: Achievement; Affect; Child; Classification; Comprehension; Data; Databases; Disabled Persons; Dizygotic Twins; Florida; Genetic; Goals; Grant; Growth; Heritability; Learning; Learning Disabilities; Measures; Monitor; Performance; Quantitative Genetics; Reader; Reading; Reporting; Sampling; Schools; Time; Twin Multiple Birth; Writing; disability; fifth grade; kindergarten

Project III entails an examination of the Florida's Progress Monitoring and Reporting Network (PMRN) database containing multiple measures of multiple reading constructs on 300,000 children attending underachieving schools in the state of Florida. Approximately 124,000 new children enter the database each year in one of the six grade levels in which data are collected: kindergarten through Fifth grade. This extensive database is uniquely equipped to answer questions related to each of the six Center grant goals. It will be used to estimate the percentages of struggling readers who fit alternative classification criteria for learning disability in various domains (e.g., impaired decoding, impaired comprehension, etc.). It also will be used to examine how alternative classification criteria for learning disability (e.g., unexplained low achievement, inadequate growth) are related (i.e., do they classify the same children as learning disabled). We will examine the predictive validity of alternative classification criteria for learning disability, amd environmental variables in relation to alternative classifications (e.g., SES, performance level of the school, etc.) and their predictive validity. For the quantitative genetic studies, we will identify an usually large number (N = 9,000) of identical and fraternal twins within the PMRN sample in order to examine genetic and environmental influence on reading constructs, their relationships to each other, and to their growth over time. We will use the sample within the PMRN to examine differential heritability of reading ability vs. disability defined in alternative ways.

项目III需要对佛罗里达州的进度监测和报告网络(PMRN)进行审查 数据库包含对300,000名儿童的多种阅读结构的多个测量 佛罗里达州成绩不佳的学校。每个约有124,000名新儿童进入数据库 在收集数据的六个年级中的一个年级：幼儿园到五年级。这 庞大的数据库是独一无二的，可以回答与六个中心奖助金目标相关的问题。它 将用于估计符合其他分类标准的困难读者的百分比 不同领域的学习障碍(例如，解码障碍、理解障碍等)。它也将是 用于检查学习障碍的替代分类标准(例如，原因不明的低 成就、成长不足)是相关的(即，他们是否将同样的儿童归类为学习障碍)。 我们将检验学习障碍的其他分类标准的预测有效性。 与替代分类有关的环境变量(例如，SES，学校的表现水平， 等)以及它们的预测有效性。对于数量遗传学研究，我们将确定一个通常较大的 PMRN样本中同卵双胞胎和异卵双胞胎的数量(N=9000)，以检查遗传和 环境对阅读结构、它们之间的关系以及它们的成长的影响 时间到了。我们将使用PMRN中的样本来检验阅读能力与阅读能力的不同遗传度。 以其他方式定义的残疾。