通过招募调节性淋巴细胞来解决牙周炎并使其再生-猫眼课题宝

通过招募调节性淋巴细胞来解决牙周炎并使其再生

批准号：

8112200

负责人：

STEVEN R LITTLE

金额：

$29.42万

依托单位：

UNIVERSITY OF PITTSBURGH AT PITTSBURGH

依托单位国家：

美国

项目类别：

财政年份：

2010

资助国家：

美国

项目状态：

已结题

起止时间：

2010-09-15 至 2011-08-31

来源：

https://reporter.nih.gov/project-details/8112200

关键词：

Acute Address Affect American Anti-Inflammatory Agents Anti-inflammatory Arthritis Attenuated Autoimmune Diseases Autoimmune Process BMP2 gene BMP4 BMP7 gene Biological Biological Assay Bone Regeneration Bone Resorption CCL22 gene Cardiovascular Diseases Cells Chemotactic Factors Chemotaxis Clinical Control Groups Data Degenerative polyarthritis Detection Diabetes Mellitus Disease Disease Progression Drug Delivery Systems Drug Formulations Effectiveness Engineering Environment Enzyme-Linked Immunosorbent Assay Equilibrium Etiology FDA approved Functional disorder Future Gingiva Glycolates Homeostasis Immune Immune response Immune system Immunology In Situ In Vitro Incidence Infection Inflammation Inflammatory Inflammatory Response Interferon Type II Interleukin-10 Interleukin-17 Interleukin-4 Kidney Diseases Knockout Mice Laboratories Lead Lesion Leukocytes Ligaments Literature Lung diseases Lymphocyte Lymphocyte Subset Matrix Metalloproteinases Mediating Modeling Molecular Biology Monitor Mus Natural regeneration Nature Oral health Osteocalcin Osteoclasts Osteogenesis Patients Pattern Periodontal Diseases Periodontitis Periodontium Pharmaceutical Preparations Physiological Play Polymers Population Positioning Attribute Premature Birth Prevalence Process Proteins Public Health Publishing Reaction Recruitment Activity Regulatory T-Lymphocyte Research Research Personnel Resolution Role Severities Side Specificity Symptoms System Systemic infection TNFSF11 gene Temporomandibular Joint Testing Therapeutic Time Tissue-Specific Gene Expression Tissues Tooth Loss Transforming Growth Factor beta Tumor Necrosis Factor-alpha Universities Vasoactive Intestinal Peptide Work Wound Healing arm base bone cell motility chemokine chemokine receptor controlled release craniofacial cytokine design follow-up human TNF protein in vivo inflammatory marker killings mouse model neutrophil osteogenic pathogen periapical periodontopathogen premature protein expression public health relevance residence response tissue regeneration

期刊论文(2)

专著(0)

科研奖励(0)

会议论文

Characterization of the Protective Role of Regulatory T Cells in Experimental Periapical Lesion Development and Their Chemoattraction Manipulation as a Therapeutic Tool.

DOI： 10.1016/j.joen.2015.09.022

发表时间： 2016-01

期刊：

Journal of endodontics

影响因子： 4.2

作者：

[Francisconi CF, Vieira AE, Biguetti CC, Glowacki AJ, Trombone AP, Letra A, Menezes Silva R, Sfeir CS, Little SR, Garlet GP]

通讯作者： Garlet GP

Combined Hydrogel/Microparticle Eye Drops for Sustained Delivery of Glaucoma Medication

批准号：

9186545
项目类别：
资助金额：

$33.18万
财政年份：

2014
负责人：

STEVEN R LITTLE
依托单位：

UNIVERSITY OF PITTSBURGH AT PITTSBURGH

Combined Hydrogel/Microparticle Eye Drops for Sustained Delivery of Glaucoma Medication

批准号：

8817604
项目类别：
资助金额：

$32.69万
财政年份：

2014
负责人：

STEVEN R LITTLE
依托单位：

UNIVERSITY OF PITTSBURGH AT PITTSBURGH

Treatment of Periodontitis via Recruitment of Regulatory Lymphocytes

批准号：

8321474
项目类别：
资助金额：

$35.4万
财政年份：

2011
负责人：

STEVEN R LITTLE
依托单位：

UNIVERSITY OF PITTSBURGH AT PITTSBURGH

Treatment of Periodontitis via Recruitment of Regulatory Lymphocytes

批准号：

8522273
项目类别：
资助金额：

$33.99万
财政年份：

2011
负责人：

STEVEN R LITTLE
依托单位：

UNIVERSITY OF PITTSBURGH AT PITTSBURGH

Treatment of Periodontitis via Recruitment of Regulatory Lymphocytes

批准号：

8723640
项目类别：
资助金额：

$35.4万
财政年份：

2011
负责人：

STEVEN R LITTLE
依托单位：

UNIVERSITY OF PITTSBURGH AT PITTSBURGH

Treatment of Periodontitis via Recruitment of Regulatory Lymphocytes

批准号：

8108000
项目类别：
资助金额：

$36.69万
财政年份：

2011
负责人：

STEVEN R LITTLE
依托单位：

UNIVERSITY OF PITTSBURGH AT PITTSBURGH

海外基金