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Comprehensive Assessment of alpha/beta T-Cell Receptor Diversity

Comprehensive Assessment of alpha/beta T-Cell Receptor Diversity
α/β T 细胞受体多样性的综合评估
批准号：
8141927
负责人：
Harlan S. Robins
金额：
$39.6万
依托单位：
FRED HUTCHINSON CANCER RESEARCH CENTER
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-09-15 至 2012-08-31
来源：
https://reporter.nih.gov/project-details/8141927
关键词：
AcuteAdultAlgorithmsAntigen ReceptorsAntiviral AgentsAppearanceBiological AssayBiological ModelsBlood specimenCD4 Positive T LymphocytesCD8-Positive T-LymphocytesCD8B1 geneCell physiologyCellsCodeComplementary DNAContractsDNA SequenceDataData SetDevelopmentFoundationsFrequenciesFutureHumanImmune responseImmune systemImmunizationJointsLeftLifeLymphocyteMeasuresMemoryMethodsMiningModelingMolecularNatural HistoryPopulationPopulation DynamicsPopulation HeterogeneityProceduresProcessPropertyRelative (related person)ResolutionSorting - Cell MovementSurfaceSystemT cell responseT-LymphocyteTRA@ gene clusterTRB@ gene clusterTechnologyTimeVaccinationVaccinesViremiaVirusVirus DiseasesYellow FeverYellow Fever Vaccinealpha-beta T-Cell Receptorbasecohortcomputerized data processingcomputerized toolsdata structureinsightinterestnovelnovel vaccinesperipheral bloodprogramspublic health relevancereceptorresponsesingle moleculevolunteer

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期刊论文(2)
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会议论文
Deep sequencing of the human TCRγ and TCRβ repertoires suggests that TCRβ rearranges after αβ and γδ T cell commitment.
DOI： 10.1126/scitranslmed.3002536
发表时间： 2011-07-06
期刊： Science translational medicine
影响因子： 17.1
作者： [Sherwood AM, Desmarais C, Livingston RJ, Andriesen J, Haussler M, Carlson CS, Robins H]
通讯作者： Robins H
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Deep sequencing for minimal residual disease detection in Acute Lymphoblastic Leu
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