Novel viral element in pathogen recognition receptor signaling by hepatitis C vir
Novel viral element in pathogen recognition receptor signaling by hepatitis C vir
批准号:
8130414
负责人:
JINAH CHOI
金额:
$30.4万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-09-07 至 2012-08-31
关键词:
AffectAmino Acid SequenceAntibodiesAntiviral AgentsBe++ elementBerylliumBiological ProcessCellsChronicChronic Hepatitis CCirrhosisCodeCodon NucleotidesCore ProteinDNA Sequencing FacilityDataDevelopmentDouble-Stranded RNAElementsFamilyFlaviviridaeGenesGenotypeGoalsHepatitis CHepatitis C virusHeterogeneityHumanImmuneImmune responseIndiumIndividualInfectionIntegration Host FactorsInterferon Type IInterferon-alphaInterferonsInvestigationLaboratoriesLeadLengthLiverLiver diseasesMass Spectrum AnalysisMetabolicMolecular BiologyMonoclonal AntibodiesMutationNatural ImmunityNucleotidesOutcomePathogenesisPathway interactionsPatientsPegylated Interferon AlfaPeptide HydrolasesPoly I-CPrimary carcinoma of the liver cellsProteinsPublic HealthRNARNA VirusesReading FramesReceptor SignalingResistanceRetinoic Acid ReceptorRibavirinRibosomal FrameshiftingRoleSignal PathwaySignal TransductionSiteStructureT cell responseTestingTranslation InitiationTretinoinVaccinesViralViral ProteinsVirionVirus Replicationanti-hepatitis Chepatoma cellhuman TLR3 proteinimmunoreactivityimprovedinterferon therapymutantnovelpathogenprotein expressionpublic health relevancereceptorresponsestemviral RNAvirus corevirus host interaction
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
Ethanol and reactive species increase basal sequence heterogeneity of hepatitis C virus and produce variants with reduced susceptibility to antivirals.
乙醇和活性物质会增加丙型肝炎病毒的基础序列异质性,并产生抗病毒药物敏感性降低的变体。
DOI:
10.1371/journal.pone.0027436
发表时间:
2011
期刊:
PloS one
影响因子:
3.7
作者:
[Seronello,Scott, Montanez,Jessica, Presleigh,Kristen, Barlow,Miriam, Park,SeungBum, Choi,Jinah]
通讯作者:
Choi,Jinah
DOI:
10.1371/journal.pone.0158419
发表时间:
2016
期刊:
PloS one
影响因子:
3.7
作者:
[Park SB, Seronello S, Mayer W, Ojcius DM]
通讯作者:
Ojcius DM
Hepatocyte Nox proteins in the pathogenesis of hepatocellular carcinoma
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批准号:8462939
-
项目类别:
-
资助金额:$28.13万
-
财政年份:2012
-
负责人:JINAH CHOI
-
依托单位:
Hepatocyte Nox proteins in the pathogenesis of hepatocellular carcinoma
-
批准号:8238851
-
项目类别:
-
资助金额:$31.11万
-
财政年份:2012
-
负责人:JINAH CHOI
-
依托单位:
Hepatocyte Nox proteins in the pathogenesis of hepatocellular carcinoma
-
批准号:8625274
-
项目类别:
-
资助金额:$29.38万
-
财政年份:2012
-
负责人:JINAH CHOI
-
依托单位:
Hepatocyte Nox proteins in the pathogenesis of hepatocellular carcinoma
-
批准号:8827271
-
项目类别:
-
资助金额:$27.66万
-
财政年份:2012
-
负责人:JINAH CHOI
-
依托单位:
海外基金