Fas pathway in organ-specific tolerance and autoimmunity
Fas pathway in organ-specific tolerance and autoimmunity
批准号:
8124074
负责人:
Abdel Rahim Hamad
金额:
$41.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-09-01 至 2012-08-31
关键词:
AblationAcuteAffectAgeAllogenicAnimal ModelAntibodiesAntigensApoptoticAutoimmune DiabetesAutoimmune DiseasesAutoimmune ProcessAutoimmunityB-Lymphocyte SubsetsB-LymphocytesBeta CellBiological AssayBone MarrowCD8B1 geneCaspaseCell DeathCellsCessation of lifeChildChimera organismChronicDataDendritic CellsDevelopmentDiabetes MellitusDiseaseFrequenciesGenesGeneticGoalsHeterozygoteHomeostasisHost DefenseHyperglycemiaImmune responseImmunosuppressionImmunotherapyInbred NOD MiceInfiltrationInsulinInsulin-Dependent Diabetes MellitusInterleukin-10InvestigationIslets of Langerhans TransplantationKnock-outLigandsMediatingMultiple SclerosisMusMutationMyeloid CellsNuclearOrganPancreasPathogenesisPathway interactionsPhysical condensationPlayPopulationPreventionProcessPublishingRecruitment ActivityResistanceRoleSignal TransductionSilicosisSourceStagingSurfaceSyndromeSystemT-LymphocyteTNFRSF5 geneTestingTherapeuticTimeTransplantationTumor Necrosis Factor Ligand Superfamily Member 6cell typechemokinechronic autoimmune diseasecytokinedesigninsightinterestisletlymph nodesneutralizing monoclonal antibodiesnovelnovel therapeuticspreventprotective effectpublic health relevanceresearch studytherapeutic target
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海外基金