Regulation of Bacteroides fragilis multidrug efflux pumps

脆弱拟杆菌多药外排泵的调节

• 批准号: 8084383
• 负责人: Hannah Wexler
• 金额: $ 31.8万
• 依托单位: BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-06 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8084383
• 关键词: Accounting; Aerobic; Aerobic Bacteria; Affect; Anaerobic Bacteria; Anti-Infective Agents; Antibiotic Resistance; Antibiotics; Antimicrobial Resistance; Area; Bacteremia; Bacteria; Bacterial Genome; Bacterial Infections; Bacteroides; Bacteroides fragilis; Bile fluid; Binding; Biochemical; Biological; Biological Assay; Biology; Cessation of life; Chronic; Clinical; Code; Collection; Colon; Communicable Diseases; Communities; Complex; Consensus; Data; Development; Disease; Drug Efflux; Environment; Escherichia coli; Explosion; Exposure to; Face; Family; Foundations; Frequencies; Funding; Funding Agency; Gene Expression Profile; Genes; Genetic Transcription; Gram-Negative Bacteria; Hand; Health; Healthcare; Homologous Gene; Human; Industry; Infection; Knowledge; Laboratories; Lead; Life; Mediating; Metronidazole; Microbial Biofilms; Molecular; Molecular Genetics; Morbidity - disease rate; Multi-Drug Resistance; Nosocomial Infections; One-Step dentin bonding system; Operon; Organism; Orphan; Outcome; Outcome Study; Outcomes Research; Oxygen; Pathology; Pathway interactions; Patients; Pharmaceutical Preparations; Pharmacologic Substance; Phenotype; Predisposition; Probability; Promoter Regions; Public Health; Publications; Publishing; Pump; Race; Regimen; Regulation; Regulon; Reporting; Research; Research Personnel; Resistance; Resistance development; Resources; Role; Scientist; Solid; Stress; Structure; Surface; System; Therapeutic; Time; Transcript; Transcription factor genes; United States; Up-Regulation; Veterans; Virulence; Virulence Factors; Virulent; Voice; Work; abdominal wall; adverse outcome; antimicrobial; bacterial resistance; biological research; capsule; clinical efficacy; combat; cost; drug development; efflux pump; functional genomics; genome sequencing; global environment; gut microbiota; information gathering; inhibitor/antagonist; member; methicillin resistant Staphylococcus aureus; mortality; mutant; novel; overexpression; pathogen; pathogenic bacteria; resistance mechanism; resistant strain; salicylate; sensor; stressor; transcription factor

项目成果

Transposon mutagenesis of Bacteroides fragilis using a mariner transposon vector.

使用水手转座子载体对脆弱拟杆菌进行转座子诱变。

• DOI: 10.1016/j.anaerobe.2013.04.012
• 发表时间: 2013
• 期刊: Anaerobe
• 影响因子: 2.3
• 作者: Veeranagouda,Yaligara;Husain,Fasahath;Wexler,HannahM
• 通讯作者: Wexler,HannahM