Novel mechanisms of Ephrin-A reverse signaling in neuronal migration

Ephrin-A 神经元迁移中反向信号传导的新机制

• 批准号: 8089002
• 负责人: PHILIP F COPENHAVER
• 金额: $ 38.32万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8089002
• 关键词: Acute; Address; Affinity; Apoptosis; Behavior; Biochemical; Biological Assay; Biological Models; Brain; Brain Injuries; Brain Neoplasms; Candidate Disease Gene; Cell Culture Techniques; Cells; Cleaved cell; Data; Development; Drosophila genus; Ectopic Expression; Embryo; Enteral; Enteric Nervous System; Eph Family Receptors; Ephrins; Glioblastoma; Goals; Image; Injection of therapeutic agent; Injury; Label; Lesion; Ligands; Link; Manduca; Manduca sexta; Mediating; Membrane; Membrane Proteins; Methods; Migration Assay; Modality; Modeling; Muscle Cells; Natural regeneration; Neoplasm Metastasis; Nervous system structure; Neurologic; Neurons; Orthologous Gene; Pathway interactions; Phosphoric Monoester Hydrolases; Phosphotransferases; Play; Preparation; Process; Protein Isoforms; Protein Tyrosine Phosphatase; Proteins; Proteomics; Regulation; Rho-associated kinase; Role; Signal Pathway; Signal Transduction; Site; System; Testing; Therapeutic; Time; adapter protein; base; cell motility; cell type; embryo culture; human PTPRT protein; in vivo; insight; migration; molecular size; nervous system disorder; neurogenesis; neuronal guidance; novel; novel diagnostics; novel therapeutics; receptor; receptors for activated C kinase; research study; response; rho; secretase; src-Family Kinases; synthetic construct; therapeutic target; tool