INVESTIGATION OF METAL ION CONCENTRATION FOLLOWING TOTAL HIP ARTHROPLASTY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 一项试验性研究，比较了以前接受过陶瓷对金属和金属对金属轴承表面全髋关节置换术的患者体内钴和铬的系统浓度。次要目标包括评估X线片上的骨溶解，潜在的种植体存活率的长期分析，以及两个患者群体中的癌症发生率。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A pilot study to compare systemic concentrations of cobalt and chromium in patients that have previously undergone total hip arthroplasties with ceramic-on-metal and metal-on-metal bearing surfaces. Secondary goals include an assessment for osteolysis on radiographs, potential long-term analysis of implant survivability, and cancer rates in the two patient populations.