AN FMRI STUDY OF AFFECTIVE PROCESSING IN EPILEPSY AND DEPRESSION

癫痫和抑郁症情感处理的 FMRI 研究

• 批准号: 8167268
• 负责人: ALAN ETTINGER
• 金额: $ 0.17万
• 依托单位: FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167268
• 关键词: Affective; Brain region; Comorbidity; Computer Retrieval of Information on Scientific Projects Database; Disease; Epilepsy; Functional Magnetic Resonance Imaging; Funding; Grant; Institution; Mental Depression; Pathology; Patients; Pattern; Persons; Process; Research; Research Personnel; Resources; Source; Syndrome; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Depression is a common comorbidity among persons with epilepsy. Many believe that depression in epilepsy is distinct from that seen in primary depression; this syndrome has been termed the interictal dysphoric disorder. Functional magnetic resonance imaging (fMRI) studies examining affective processing in primary depression have identified brain regions associated with the pathology and symptomatology of primary depression; however there is little information about fMRI patterns associated with depression in epilepsy. We seek to clarify whether there is a unique functional activation pattern in patients with epilepsy and depression.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 抑郁症是癫痫患者中常见的一种共病。许多人认为癫痫患者的抑郁与原发性抑郁症不同；这种综合征被称为发作间歇性焦虑症。功能磁共振成像(FMRI)研究检测了原发性抑郁症的情感处理，已经确定了与原发性抑郁症的病理和症状学相关的脑区；然而，关于癫痫患者与抑郁症相关的fMRI模式的信息很少。我们试图阐明癫痫和抑郁症患者是否存在一种独特的功能激活模式。