Curricular and Collaborative Expansion of the Medical Device Innovation & Entrepreneurship Program

 描述(由申请人提供)：本申请的广泛和长期目标是通过为生物医学工程师以及医疗器械开发领域的其他合作学科创造基于行动学习的新型教育体验，直接影响美国的转化型医疗器械开发，并减少临床实践/商业化。这份NIH R25研究和教育提案旨在实现辛辛那提大学已经成功的医疗器械创新和创业计划(MDIEP)的课程和协作飞跃。MDIEP目前是生物医学工程本科学位的旗舰跨学科高级顶峰体验项目，该项目还邀请了COM的医生、来自CEAS其他学科(EE、ME)、设计学院和商业学院的学生与医生和项目教师(Pi S Haridas和Privitera)合作开发新的医疗器械创新。虽然该计划已经得到了很好的确立和国家认可，但在改善临床问题定义、现实和功能原型、顶峰前课程需求以及扩大跨学科合作方面仍存在资金方面的挑战。为了达到这些目标，我们建议mDIEP的多方面课程和合作扩展，并在这笔赠款的5年内实现以下具体目标。SA1：通过建立新的临床轮换和实践奖学金经验，加强与医学院的临床合作和临床实践经验，以改进针对临床问题陈述制定的潜在需求识别过程。SA2：课程改革，以满足先进医疗器械原型的需求，包括培训学生先进的CAD/CAM、添加剂制造、基于导管的设备的设计和制造，以及形状记忆/超弹性镍钛合金植入物/设备的设计/原型制作。SA3：用于临床前测试的增强型高级设计-工程原型，显著提高由学生设计的医疗设备的质量，使其能够进行现实的临床前测试并转化为知识产权。SA4：通过正式确定与其他工程专业以及包括设计和商业在内的其他学院的关系，扩大学院和学校之间的合作。

 DESCRIPTION (provided by applicant): The broad and long term objective of this application is to directly impact translational medical device development in the USA via the creation of a novel action learning based educational experience for Biomedical engineers as well as other collaborating disciplines in the field of medical device development and reduction to clinical practice/commercialization. This NIH R25 Research and Education proposal aims to achieve a curricular and collaborative leap forward of an already successful Medical Device Innovation and Entrepreneurship Program (MDIEP) at the University of Cincinnati. MDIEP is currently the flagship interdisciplinary senior capstone experience for the undergraduate degree in Biomedical Engineering which also engages physicians from COM, students from other CEAS disciplines (EE, ME), the Schools of Design and Business working with physicians and program faculty (PI s Haridas and Privitera) to develop new medical device innovations. While program is well established and nationally recognized, there still remain challenges in terms of funding for improved clinical problem definition, realistic and functional prototyping, pre-capstone curricular needs, and expansion of collaboration across disciplines. To address these goals, we are proposing a multi-faceted curricular and collaborative expansion of mDIEP with the following specific aims to be accomplished in the 5 year period of this grant. SA1: Enhancement of Clinical Collaborations and Clinical Practicum Experience with the College of Medicine through the institution of a new Clinical Rotation & Practicum Fellowship experience to improve the latent needs identification process towards clinical problem statement development. SA2: Curricular changes to address needs in advanced medical device prototyping including training students in advanced CAD/CAM, additive manufacturing, design and fabrication of catheter based devices, and design/prototyping of shape memory/superelastic NiTiNOL implants/devices. SA3: Enhanced Senior Design-Engineering Prototypes for Preclinical Testing to improve significantly the quality of medical devices designed by students enabling realistic preclinical testing and translation to intellectual property. SA4: Expand collaboration across Colleges and Schools by formalizing the relationships with other engineering programs, as well other colleges including design and business.