Interdisciplinary Training in Pathobiology and Rehabilitation Medicine

描述(由申请者提供)：该培训计划的主要目标是将新兴科学家培养成转化型康复研究的未来领导者，他们特别具备测试和传播新的康复策略的能力，这些策略将在面临慢性病管理的情况下缓解功能障碍和降低生活质量。这一目标将通过利用提供无数资源的异常丰富的机构环境以及由致力于培训和职业发展的基础和临床研究导师组成的互补和协作团队来实现。博士后和博士后实习生将从两年的跨学科培训中受益，这些培训仔细地融合了三个核心层面的科学研究：i)疾病的细胞和分子病理生物学；ii)康复 科学和运动生理学；以及iii)康复医学(即临床试验)。训练将发生在两个集中力量的领域之一：1)神经肌肉骨骼和运动障碍；或2)心肺和新陈代谢疾病。有培训机会的交叉主题包括癌症和老龄化。博士前实习生将从竞争激烈和多样化的全国范围内被生物医学研究生计划或康复科学计划录取的学生中挑选出来。国家招收的博士后实习生将通过博士后教育办公室和临床与转化科学中心赞助的结构化计划和课程，获得宝贵的临床和转化性研究培训和职业发展。每个学员的主要导师和翻译指导团队将从医学院(生理学、物理医学和康复、神经病学、细胞生物学、病理学、遗传学、心脏病学、老年病学)、健康专业(物理疗法、职业疗法和营养科学)、公共卫生(流行病学)和艺术与科学(心理学)的专家项目教员中挑选。学员、导师和翻译指导团队将共同制定个人发展计划，该计划将每半年由执行委员会批准和监督一次。该计划将包括必修和选修的教学课程、实验室和临床研究、期刊俱乐部、研讨会、在地方和国家会议上的科学陈述，以及负责任的研究行为培训。学习进行和发表高影响力的研究将是培训计划的主要重点。博士后实习生还将从基金撰写和实验室管理课程中受益。该计划将从第一年指导两名博士后和两名博士后实习生增加到每年四名，并将采取 利用成熟的最佳做法，成功地招聘人数偏低的少数群体和残疾人。作为美国国立卫生研究院资助的25个顶级学术医疗中心，拥有80多个最先进的科学核心设施和25个大学范围内的跨学科研究中心，阿拉巴马大学伯明翰分校处于非常有利的地位，可以培养真正的翻译科学家，为康复医学领域提供尖端研究。

DESCRIPTION (provided by applicant): The overarching goal of this training program is to develop burgeoning scientists into future leaders in translational rehabilitation research who are specifically equipped to test and disseminate novel rehabilitative strategies that will alleviate functional impairment and compromised life quality in the face of chronic disease management. This goal will be met by taking advantage of an exceptionally rich institutional environment that offers myriad resources and a complementary and collaborative team of basic and clinical research mentors committed to training and career development. Predoctoral and postdoctoral trainees will benefit from two years of interdisciplinary training that carefully meld three core levels of scientific inquiry: i) cellular and molecular pathobiology of disease; ii) rehabilitation science and exercise physiology; and iii) rehabilitation medicine (i.e. clinical trials). Training ill occur in one of two areas of concentrated strength: 1) Neuromusculo- skeletal and Movement Disorders; or 2) Cardiopulmonary and Metabolic Diseases. Cross-cutting themes with training opportunities include cancer and aging. Predoctoral trainees will be selected from a highly competitive and diverse national pool of students admitted to either the Graduate Biomedical Sciences program or Rehabilitation Science program. Nationally recruited postdoctoral trainees will gain invaluable clinical and translational research training and career development via structured programs and courses sponsored by the Office of Postdoctoral Education and the Center for Clinical and Translational Science. Each trainee's primary mentor and Translational Mentoring Team will be drawn from expert program faculty in the Schools of Medicine (physiology, physical medicine & rehabilitation, neurology, cell biology, pathology, genetics, cardiology, geriatrics), Health Professions (physical therapy, occupational therapy, and nutrition sciences), Public Health (epidemiology), and Arts & Sciences (psychology). Together the trainee, mentor, and Translational Mentoring Team will craft an individual development plan, which will be approved and monitored semi-annually by the Executive Committee. The plan will include required and elective didactic courses, laboratory and clinical research, journal clubs, seminars, scientific presentations locally and at national meetings, and training in the responsible conduct of research. Learning to conduct and publish high-impact research will be a primary focus of the training program. Postdoctoral trainees will also profit from courses on grant writing and laboratory management. The program will grow from mentoring two predoctoral and two postdoctoral trainees in the first year to four of each annually, and will take advantage of well-established best practices for successful recruitment of underrepresented minorities and individuals with disabilities. As a top 25 NIH-funded academic medical center with over 80 state-of-the-art scientific core facilities and 25 University-wide, interdisciplinary reseach centers, the University of Alabama at Birmingham is remarkably well-positioned to cultivate truly translational scientists equipped to drive the field of rehabilitation medicine with cutting edge research.