Interdisciplinary Training in Pathobiology and Rehabilitation Medicine

描述（由申请人提供）：该培训项目的总体目标是将新兴科学家培养成转化康复研究的未来领导者，他们专门配备测试和传播新的康复策略，以减轻慢性疾病管理中的功能损伤和生活质量下降。这一目标将通过利用一个提供无数资源的异常丰富的机构环境和一个致力于培训和职业发展的基础和临床研究导师的互补和协作团队来实现。博士前和博士后学员将受益于两年的跨学科培训，这些培训将仔细融合三个核心的科学探究水平：i)疾病的细胞和分子病理生物学；(二)康复

DESCRIPTION (provided by applicant): The overarching goal of this training program is to develop burgeoning scientists into future leaders in translational rehabilitation research who are specifically equipped to test and disseminate novel rehabilitative strategies that will alleviate functional impairment and compromised life quality in the face of chronic disease management. This goal will be met by taking advantage of an exceptionally rich institutional environment that offers myriad resources and a complementary and collaborative team of basic and clinical research mentors committed to training and career development. Predoctoral and postdoctoral trainees will benefit from two years of interdisciplinary training that carefully meld three core levels of scientific inquiry: i) cellular and molecular pathobiology of disease; ii) rehabilitation science and exercise physiology; and iii) rehabilitation medicine (i.e. clinical trials). Training ill occur in one of two areas of concentrated strength: 1) Neuromusculo- skeletal and Movement Disorders; or 2) Cardiopulmonary and Metabolic Diseases. Cross-cutting themes with training opportunities include cancer and aging. Predoctoral trainees will be selected from a highly competitive and diverse national pool of students admitted to either the Graduate Biomedical Sciences program or Rehabilitation Science program. Nationally recruited postdoctoral trainees will gain invaluable clinical and translational research training and career development via structured programs and courses sponsored by the Office of Postdoctoral Education and the Center for Clinical and Translational Science. Each trainee's primary mentor and Translational Mentoring Team will be drawn from expert program faculty in the Schools of Medicine (physiology, physical medicine & rehabilitation, neurology, cell biology, pathology, genetics, cardiology, geriatrics), Health Professions (physical therapy, occupational therapy, and nutrition sciences), Public Health (epidemiology), and Arts & Sciences (psychology). Together the trainee, mentor, and Translational Mentoring Team will craft an individual development plan, which will be approved and monitored semi-annually by the Executive Committee. The plan will include required and elective didactic courses, laboratory and clinical research, journal clubs, seminars, scientific presentations locally and at national meetings, and training in the responsible conduct of research. Learning to conduct and publish high-impact research will be a primary focus of the training program. Postdoctoral trainees will also profit from courses on grant writing and laboratory management. The program will grow from mentoring two predoctoral and two postdoctoral trainees in the first year to four of each annually, and will take advantage of well-established best practices for successful recruitment of underrepresented minorities and individuals with disabilities. As a top 25 NIH-funded academic medical center with over 80 state-of-the-art scientific core facilities and 25 University-wide, interdisciplinary reseach centers, the University of Alabama at Birmingham is remarkably well-positioned to cultivate truly translational scientists equipped to drive the field of rehabilitation medicine with cutting edge research.