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Mitochondrial-targeted CoQ: Metabolic and Redox Effects and role in Diabetes

Mitochondrial-targeted CoQ: Metabolic and Redox Effects and role in Diabetes
线粒体靶向 CoQ：代谢和氧化还原效应及其在糖尿病中的作用
批准号：
8195611
负责人：
William Irving Sivitz
金额：
$0.0万
依托单位：
IOWA CITY VA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-07-01 至 2014-06-30
来源：
https://reporter.nih.gov/project-details/8195611
关键词：
AccountingAddressAgingAnimal Disease ModelsAnimalsAntioxidantsAortaAttentionBiological AssayBlood VesselsCarbon DioxideCell SeparationCellsChargeChemicalsComplexCouplingCultured CellsDataDiabetes MellitusDiabetic mouseDiseaseEffectivenessElectron TransportEndothelial CellsEnzymesEquilibriumFatty AcidsFatty acid glycerol estersFunctional disorderFundus photographyGasesGlucoseIn VitroInsulinInsulin ResistanceKnowledgeLeadLifeLipid BilayersLipid PeroxidationLipidsMeasuresMediatingMembraneMembrane PotentialsMetabolicMitochondriaModelingModificationMolecularMusMuscleMuscle CellsMuscle MitochondriaNeurodegenerative DisordersNutrientObese MiceObesityOxidation-ReductionOxygenOxygen ConsumptionPathologyProductionPropertyProteinsProtonsQuinonesReactive Oxygen SpeciesRelative (related person)Report (document)ReportingResearchResearch PersonnelRespirationRespiratory ChainRetinal DiseasesRodentRoleSiteSourceSuccinatesSuperoxidesSystemTechnologyTherapeutic AgentsUbiquinoneVeteransVitamin EWorkanalogbasecell typediabeticeffective therapyfatty acid oxidationfeedingflexibilityglucose metabolismglycationin vivoinsulin sensitivitylipid metabolismmimeticsmitochondrial dysfunctionmitochondrial membranemitoquinonenoveloxidationoxidative damageprotective effectrespiratorysemiquinoneubiquinol

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