CaMKII mediates vascular smooth cell hypertrophy and hypertension

CaMKII介导血管平滑细胞肥大和高血压

• 批准号: 8195605
• 负责人: Isabella Maria Grumbach
• 金额: --
• 依托单位: IOWA CITY VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8195605
• 关键词: Address; Affect; Angiotensin II; Animal Model; Animals; Antihypertensive Agents; Aorta; Arteries; Atherosclerosis; Blood Pressure; Blood Vessels; Calcium; Calmodulin; Calmodulin 1; Cardiovascular Diseases; Cardiovascular system; Cause of Death; Cell physiology; Cells; Chronic; Clinical Trials; Collaborations; Data; Development; Disease; Environment; Funding; Goals; HDAC4 gene; Hand; Healthcare; Heart failure; Hypertension; Hypertrophy; In Vitro; Knowledge; Laboratories; Medial; Mediating; Molecular; Molecular Biology Techniques; Morbidity - disease rate; Muscle function; Pathway interactions; Pharmaceutical Preparations; Phosphotransferases; Physiology; Polypharmacy; Protein Chemistry; Protein-Serine-Threonine Kinases; Reporting; Research; Resistance; Risk Factors; Role; Signal Pathway; Signal Transduction; Smooth Muscle; Smooth Muscle Myocytes; Specificity; Stroke; Techniques; Testing; Therapeutic Agents; Vascular Smooth Muscle; Vascular remodeling; Vasoconstrictor Agents; Vasomotor; Veterans; Work; base; constriction; derepression; fighting; hypertension control; hypertension treatment; in vivo; in vivo Model; inhibitor/antagonist; intercellular communication; mortality; mouse model; muscle hypertrophy; novel; novel strategies; novel therapeutic intervention; novel therapeutics; pressure; prevent; programs; research study; response; treatment strategy; vasoconstriction