Loss of Filamin A Nuclear Localization in Prostate Cancer Progression

丝蛋白的丢失是前列腺癌进展中的核定位

• 批准号: 8195837
• 负责人: PARAMITA M. GHOSH
• 金额: --
• 依托单位: VA NORTHERN CALIFORNIA HEALTH CARE SYS
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8195837
• 关键词: Affect; Androgen Receptor; Androgens; Apoptosis; Benign; Biopsy; California; Cancer Patient; Castration; Cell Nucleus; Cell Survival; Cells; Clinical Trials; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Data; Deposition; Development; Diagnosis; Funding; Genetic Transcription; Goals; Growth; Hormonal; Human; In Vitro; Individual; Induction of Apoptosis; Laboratories; Malignant neoplasm of prostate; Mediating; Metastatic Prostate Cancer; Morbidity - disease rate; NCOA2 gene; NF-kappa B; Neoplasm Metastasis; Normal tissue morphology; Nuclear; PC3 cell line; Patients; Pharmaceutical Preparations; Phosphorylation; Play; Prostate; Proteins; Publications; Radical Prostatectomy; Recurrence; Resistance; Role; Signal Pathway; Steroid Receptors; System; Testing; Time; Tissues; Toxic effect; Treatment Failure; United States; Withdrawal; abstracting; cancer cell; cell behavior; cell motility; filamin; hormone therapy; inhibitor/antagonist; innovation; male; mortality; mouse model; prevent; therapeutic target; tumor; tumor progression