Role of Rho GDP dissociation inhibitors in androgen signaling in prostate cancer
Rho GDP 解离抑制剂在前列腺癌雄激素信号传导中的作用
基本信息
- 批准号:8195836
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-04-01 至 2014-03-31
- 项目状态:已结题
- 来源:
- 关键词:AffectAmino Acid SequenceAmino AcidsAndrogen ReceptorAndrogensBenignBiological AssayCancer Cell GrowthCancer EtiologyCastrationCell LineCellsCessation of lifeDNA BindingDataDevelopmentDown-RegulationEnzyme-Linked Immunosorbent AssayEvolutionFamilyFoundationsGelGenesGrowthGuanine Nucleotide Dissociation InhibitorsGuanosine Triphosphate PhosphohydrolasesHealthHealthcareHumanIL6 geneIn VitroLNCaPLeadMalignant - descriptorMalignant neoplasm of lungMalignant neoplasm of prostateMeSH ThesaurusMessenger RNAMolecularN-terminalNorthern BlottingNuclear TranslocationNude MicePC3 cell linePathway interactionsPatientsPeptide Sequence DeterminationPlayPopulationProcessProstateProstate-Specific AntigenReceptor ActivationReceptor SignalingRelapseResearchResistanceRoleSignal PathwaySignal TransductionSignaling MoleculeSiteSpecificityStagingTissuesTransactivationUnited StatesVeteransWestern BlottingWithdrawalbasecancer cellcancer diagnosiscell growthcell motilitychromatin immunoprecipitationdeprivationeffective interventioneffective therapyin vivojun Oncogeneknock-downmRNA Stabilitymalemenneoplastic cellnoveloverexpressionpreclinical studypromoterprotein degradationprotein profilingreceptor expressionresearch studyresponserhorhoB p20 GDIsmall hairpin RNAtumortumor progressiontumorigenic
项目摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Allen C Gao其他文献
INTERLEUKIN-6 ENHANCES INTRATUMORAL ANDROGEN LEVELS BY REGULATING THE EXPRESSION OF GENES MEDIATING ANDROGEN METABOLISM
- DOI:
10.1016/s0022-5347(09)60274-3 - 发表时间:
2009-04-01 - 期刊:
- 影响因子:
- 作者:
Yae Chun;Joy C Yang;Hsing-Jien Kung;Christopher P Evans;Allen C Gao - 通讯作者:
Allen C Gao
What kind of patients with castration-naïve prostate cancer can benefit from upfront docetaxel and abiraterone: A systematic review and a network meta-analysis
- DOI:
10.1016/j.urolonc.2018.09.005 - 发表时间:
2018 - 期刊:
- 影响因子:
- 作者:
Guangxi Sun;Xingming Zhang;Junru Chen;Banghua Liao;Zhenhua Liu;Jinge Zhao;Allen C Gao;Yaojing Yang;Kunpeng Shu;Jiandong Liu;Peng Zhao;Pengfei Shen;Hao Zeng - 通讯作者:
Hao Zeng
SRC FAMILY KINASE INHIBITOR AZD0530 INHIBITS GRP-MEDIATED ANDROGEN-INDEPENDENT GROWTH AND MIGRATION POSSIBLY THROUGH BOTH ANDROGEN AND ANDROGEN RECEPTOR
- DOI:
10.1016/s0022-5347(09)60739-4 - 发表时间:
2009-04-01 - 期刊:
- 影响因子:
- 作者:
Joy C Yang;Jae Yeon Chun;Hsing-Jien Kung;Allen C Gao;Christopher P Evans - 通讯作者:
Christopher P Evans
Interleukin-4 enhances prostate-specific antigen expression by activation of the androgen receptor and Akt pathway
白细胞介素-4 通过激活雄激素受体和 Akt 通路增强前列腺特异性抗原表达
- DOI:
10.1038/sj.onc.1206735 - 发表时间:
2003-09-11 - 期刊:
- 影响因子:7.300
- 作者:
Soo Ok Lee;Wei Lou;Min Hou;Sergio A Onate;Allen C Gao - 通讯作者:
Allen C Gao
NF-KB2/P52 INDUCES CASTRATION-RESISTANT PROSTATE CANCER CELL GROWTH AND ABERRANT ACTIVATION OF ANDROGEN RECEPTOR
- DOI:
10.1016/s0022-5347(09)60754-0 - 发表时间:
2009-04-01 - 期刊:
- 影响因子:
- 作者:
Nagalakshmi Nadimity;Wei Lou;Allen C Gao - 通讯作者:
Allen C Gao
Allen C Gao的其他文献
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{{ truncateString('Allen C Gao', 18)}}的其他基金
Novel therapeutics dual targeting intracrine androgen synthesis and AR for advanced prostate cancer
双靶向内分泌雄激素合成和 AR 治疗晚期前列腺癌的新型疗法
- 批准号:
10573314 - 财政年份:2022
- 资助金额:
-- - 项目类别:
Novel therapeutics dual targeting intracrine androgen synthesis and AR for advanced prostate cancer
双靶向内分泌雄激素合成和 AR 治疗晚期前列腺癌的新型疗法
- 批准号:
10449648 - 财政年份:2022
- 资助金额:
-- - 项目类别:
Novel therapeutics dual targeting intracrine androgen synthesis and AR for advanced prostate cancer
双靶向内分泌雄激素合成和 AR 治疗晚期前列腺癌的新型疗法
- 批准号:
10808574 - 财政年份:2022
- 资助金额:
-- - 项目类别:
Therapeutic targeting steroid sulfatase for advanced prostate cancer
类固醇硫酸酯酶靶向治疗晚期前列腺癌
- 批准号:
10057773 - 财政年份:2020
- 资助金额:
-- - 项目类别:
Therapeutic targeting Wnt5A signaling for advanced prostate cancer
靶向 Wnt5A 信号传导治疗晚期前列腺癌
- 批准号:
10526399 - 财政年份:2020
- 资助金额:
-- - 项目类别:
Therapeutic targeting steroid sulfatase for advanced prostate cancer
类固醇硫酸酯酶靶向治疗晚期前列腺癌
- 批准号:
10426197 - 财政年份:2020
- 资助金额:
-- - 项目类别:
Therapeutic targeting steroid sulfatase for advanced prostate cancer
类固醇硫酸酯酶靶向治疗晚期前列腺癌
- 批准号:
10622544 - 财政年份:2020
- 资助金额:
-- - 项目类别:
Therapeutic targeting steroid sulfatase for advanced prostate cancer
类固醇硫酸酯酶靶向治疗晚期前列腺癌
- 批准号:
10737796 - 财政年份:2020
- 资助金额:
-- - 项目类别:
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