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Role of Rho GDP dissociation inhibitors in androgen signaling in prostate cancer

Role of Rho GDP dissociation inhibitors in androgen signaling in prostate cancer
Rho GDP 解离抑制剂在前列腺癌雄激素信号传导中的作用
批准号：
8195836
负责人：
Allen C Gao
金额：
$0.0万
依托单位：
VA NORTHERN CALIFORNIA HEALTH CARE SYS
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-04-01 至 2014-03-31
来源：
https://reporter.nih.gov/project-details/8195836
关键词：
AffectAmino Acid SequenceAmino AcidsAndrogen ReceptorAndrogensBenignBiological AssayCancer Cell GrowthCancer EtiologyCastrationCell LineCellsCessation of lifeDNA BindingDataDevelopmentDown-RegulationEnzyme-Linked Immunosorbent AssayEvolutionFamilyFoundationsGelGenesGrowthGuanine Nucleotide Dissociation InhibitorsGuanosine Triphosphate PhosphohydrolasesHealthHealthcareHumanIL6 geneIn VitroLNCaPLeadMalignant - descriptorMalignant neoplasm of lungMalignant neoplasm of prostateMeSH ThesaurusMessenger RNAMolecularN-terminalNorthern BlottingNuclear TranslocationNude MicePC3 cell linePathway interactionsPatientsPeptide Sequence DeterminationPlayPopulationProcessProstateProstate-Specific AntigenReceptor ActivationReceptor SignalingRelapseResearchResistanceRoleSignal PathwaySignal TransductionSignaling MoleculeSiteSpecificityStagingTissuesTransactivationUnited StatesVeteransWestern BlottingWithdrawalbasecancer cellcancer diagnosiscell growthcell motilitychromatin immunoprecipitationdeprivationeffective interventioneffective therapyin vivojun Oncogeneknock-downmRNA Stabilitymalemenneoplastic cellnoveloverexpressionpreclinical studypromoterprotein degradationprotein profilingreceptor expressionresearch studyresponserhorhoB p20 GDIsmall hairpin RNAtumortumor progressiontumorigenic

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