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Mechanisms of Impaired Wound Healing Due to Ischemia

Mechanisms of Impaired Wound Healing Due to Ischemia
缺血导致伤口愈合受损的机制
批准号:
7903899
负责人:
Lisa J Gould
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-01-01 至 2012-09-30
关键词:
3-nitrotyrosineAcuteAffectAgeAge-MonthsAged, 80 and overAgingAmericanAnti-Inflammatory AgentsAnti-inflammatoryAntioxidantsApoptosisBiological AssayBiological AvailabilityBuffersCell DeathCell ProliferationCell SurvivalCell physiologyCellsChronicCollagenComorbidityConfocal MicroscopyCuprozinc Superoxide DismutaseDataDiabetes MellitusElderlyEndothelial CellsEnzymesEpidemicEpithelial CellsEquilibriumExcisionExtracellular MatrixFibroblastsFoundationsGelatinase BGenerationsGlutamate-Cysteine LigaseGlutathioneGoalsHealedHealthHealth systemHealthcareHealthcare SystemsHeart DiseasesHomeostasisHumanHydrogen PeroxideHyperoxiaHypoxiaImmunoblottingImmunohistochemistryImpaired wound healingIncidenceIndiumIndividualInflammationInflammation MediatorsInflammatoryInflammatory ResponseIntermittent ClaudicationInterstitial CollagenaseIschemiaIsoenzymesLeadLifeLimb structureLiquid substanceLiteratureLower ExtremityLucigeninMatrix Metalloproteinase InhibitorMatrix MetalloproteinasesMeasurementMeasuresMessenger RNAModelingMolecularMorbidity - disease rateNBL1 geneNatural regenerationNecrosisNitratesNitric OxideNitritesNitrogenOxidation-ReductionOxidative StressOxygenPathogenesisPathologyPatientsPeptide HydrolasesPerfusionPeripheral arterial diseasePeroxonitritePhysiologicalPlayPopulationPredispositionPrevalenceProceduresProcessProductionProtease InhibitorProtein IsoformsProteinsPublic HealthRattusReactionReactive Nitrogen SpeciesReactive Oxygen SpeciesReperfusion TherapyResidual stateRoleSignaling MoleculeSkinSkin AgingStressSuperoxide DismutaseSuperoxidesSurgical FlapsSystemTestingTimeTissue ExtractsTissue ModelTissuesVascular DiseasesVascular blood supplyVenous InsufficiencyVeteransWaterWound Healingabstractingangiogenesiscatalasecell motilitycostcytokineeffective therapyenzyme activityhealingimprovedinhibitor/antagonistkeratinocytemRNA Expressionmiddle agemigrationmimeticsnitrationnoveloxidationoxidative damagepressurepreventprotein expressionresponsesuperoxide dismutase 1synthetic enzymetissue traumawoundyoung adult

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Mechanisms of Impaired Wound Healing Due to Ischemia
Mechanisms of Impaired Wound Healing Due to Ischemia
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