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Lipid Transport, Bile Acid Synthesis, and Cholesterol Homeostasis

Lipid Transport, Bile Acid Synthesis, and Cholesterol Homeostasis
脂质运输、胆汁酸合成和胆固醇稳态
批准号：
7907772
负责人：
WILLIAM M PANDAK
金额：
$0.0万
依托单位：
VA VETERANS ADMINISTRATION HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-10-01 至 2013-09-30
来源：
https://reporter.nih.gov/project-details/7907772
关键词：
Acetyl-CoA CarboxylaseAffectAmericanAnimal ModelAtherosclerosisAttenuatedBile Acid Biosynthesis PathwayBile AcidsBindingCellsCholesterolCholesterol HomeostasisCirrhosisCyclophosphamideDataDevelopmentDiseaseEndoplasmic ReticulumEnzymesEventExtrahepaticFatty AcidsFatty-acid synthaseFibrosisGene ExpressionGenesGeneticHepaticHepatocyteHereditary DiseaseHomeostasisHydroxymethylglutaryl-CoA reductaseHypertriglyceridemiaImpairmentInflammationInjuryIntracellular Accumulation of LipidsKnock-outLipidsLiverLiver cell necrosisLiver diseasesMediatingMetabolismMitochondriaModelingNeurologicNuclear ReceptorsPathway interactionsPatient CarePatientsPeroxisome Proliferator-Activated ReceptorsPlayPopulationProductionProteinsReceptor ActivationRegulationRoleTestingTimeTissuesTriglyceridesVariantVeteransabstractingatherogenesisbasecholesterol biosynthesiseffective therapyhuman diseaselipid metabolismlipid transportnon-alcoholic fatty livernovel strategiesoverexpressionoxidationpreventpublic health relevanceresponsesensortreatment strategy

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