Use of Xenopus a system to study the trafficking,function and structure of IRBP

利用Xenopus系统研究IRBP的运输、功能和结构

• 批准号: 7920050
• 负责人: FEDERICO GONZALEZ-FERNANDEZ
• 金额: --
• 依托单位: VA WESTERN NEW YORK HEALTHCARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7920050
• 关键词: 11-cis-Retinol; 3-Dimensional; Address; Affect; African; All-Trans-Retinol; Antioxidants; Apical; Binding; Binding Sites; Biochemistry; Cell Death; Cell surface; Cells; Charge; Chemicals; Cleaved cell; Cloning; Complex; Crystallography; Disease; Escherichia coli; Excision; Fatty Acids; Funding; GRB10 gene; Goals; Human; Individual; Lead; Length; Ligand Binding; Ligand Binding Domain; Lipid Peroxidation; Mediating; Molecular; Monitor; Mus; Mutation; Occupations; Pattern; Photoreceptors; Physiological; Proteins; Research; Retina; Retinal Cone; Retinitis Pigmentosa; Retinoids; Review Literature; Rod Outer Segments; Roentgen Rays; Site; Sodium Chloride; Structure; Surface; System; Time; Transgenic Mice; Villus; Vitamin A; X ray diffraction analysis; X-Ray Diffraction; Xenopus; Xenopus sp.; interstitial retinol-binding protein; mutant; novel; oxidation; oxidative damage; photoreceptor degeneration; protein function; protein structure; protein transport; public health relevance; receptor; scaffold; trafficking; visual cycle